KR970009157B1 - Process for the high yield production of taxol by cell culture - Google Patents

Process for the high yield production of taxol by cell culture Download PDF

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Publication number
KR970009157B1
KR970009157B1 KR93010693A KR930010693A KR970009157B1 KR 970009157 B1 KR970009157 B1 KR 970009157B1 KR 93010693 A KR93010693 A KR 93010693A KR 930010693 A KR930010693 A KR 930010693A KR 970009157 B1 KR970009157 B1 KR 970009157B1
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KR
South Korea
Prior art keywords
cell
taxol
callus
cell culture
high yield
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Application number
KR93010693A
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Korean (ko)
Other versions
KR950000870A (en
Inventor
Sang-Yo Byun
Original Assignee
Green Cross Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Green Cross Corp filed Critical Green Cross Corp
Priority to KR93010693A priority Critical patent/KR970009157B1/en
Publication of KR950000870A publication Critical patent/KR950000870A/en
Application granted granted Critical
Publication of KR970009157B1 publication Critical patent/KR970009157B1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms

Abstract

Taxol and its derivatives are produced by inducing callus from the living cell of the leaves and stems of yew tree, and then by suspension culture of the callus cell in liquid medium. During the culture of callus cell, adding elicitor extracted from cell wall of phytophtora megasperma or yeast, increased jasmonic acid content in cell, and then formed Taxol produced twice. Direct addition of jasmonic acid from outside indicates the same effect.
KR93010693A 1993-06-12 1993-06-12 Process for the high yield production of taxol by cell culture KR970009157B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR93010693A KR970009157B1 (en) 1993-06-12 1993-06-12 Process for the high yield production of taxol by cell culture

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR93010693A KR970009157B1 (en) 1993-06-12 1993-06-12 Process for the high yield production of taxol by cell culture

Publications (2)

Publication Number Publication Date
KR950000870A KR950000870A (en) 1995-01-03
KR970009157B1 true KR970009157B1 (en) 1997-06-07

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ID=19357288

Family Applications (1)

Application Number Title Priority Date Filing Date
KR93010693A KR970009157B1 (en) 1993-06-12 1993-06-12 Process for the high yield production of taxol by cell culture

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KR (1) KR970009157B1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8053238B2 (en) 2005-10-31 2011-11-08 Unhwa Corporation Isolated population of plant single cells and method of preparing the same
US8247230B2 (en) 2007-09-21 2012-08-21 Unhwa Corporation Plant stem cell line derived from cambium of herbaceous plant with storage root and method for isolating the same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965438A (en) * 1995-06-07 1999-10-12 Phyton, Inc. Cryopreservation of plant cells

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8053238B2 (en) 2005-10-31 2011-11-08 Unhwa Corporation Isolated population of plant single cells and method of preparing the same
US8329471B2 (en) 2005-10-31 2012-12-11 Unhwa Corporation Isolated population of plant single cells and method of preparing same
US8247230B2 (en) 2007-09-21 2012-08-21 Unhwa Corporation Plant stem cell line derived from cambium of herbaceous plant with storage root and method for isolating the same

Also Published As

Publication number Publication date
KR950000870A (en) 1995-01-03

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