KR960705842A - N-알킬 펩티드 킬레이트 형성제, 방사핵종을 갖는 그의 금속 착물, 이들의 제조방법 및 이들 화합물을 함유한 방사성의약 조성물(n-alkyl peptide chelate formers, their metal complexes with radionuclides, processes for producing them and radio-pharmaceutical compositions containing these compound) - Google Patents
N-알킬 펩티드 킬레이트 형성제, 방사핵종을 갖는 그의 금속 착물, 이들의 제조방법 및 이들 화합물을 함유한 방사성의약 조성물(n-alkyl peptide chelate formers, their metal complexes with radionuclides, processes for producing them and radio-pharmaceutical compositions containing these compound)Info
- Publication number
- KR960705842A KR960705842A KR1019960702247A KR19960702247A KR960705842A KR 960705842 A KR960705842 A KR 960705842A KR 1019960702247 A KR1019960702247 A KR 1019960702247A KR 19960702247 A KR19960702247 A KR 19960702247A KR 960705842 A KR960705842 A KR 960705842A
- Authority
- KR
- South Korea
- Prior art keywords
- radionuclides
- compositions containing
- metal complexes
- peptide chelate
- alkyl peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/26—Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4337600A DE4337600A1 (de) | 1993-11-01 | 1993-11-01 | N-Alkyl-Peptidchelatbildner, deren Metallkomplexe mit Radionukliden, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende radiopharmazeutische Zusammesetzungen |
PCT/DE1994/001295 WO1995012610A1 (de) | 1993-11-01 | 1994-10-27 | N-alkyl-peptidchelatbildner, deren metallkomplexe mit radionukliden, verfahren zu ihrer herstellung und diese verbindungen enthaltende radiopharmazeutische zusammensetzungen |
Publications (1)
Publication Number | Publication Date |
---|---|
KR960705842A true KR960705842A (ko) | 1996-11-08 |
Family
ID=6501750
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019960702247A KR960705842A (ko) | 1993-11-01 | 1996-04-30 | N-알킬 펩티드 킬레이트 형성제, 방사핵종을 갖는 그의 금속 착물, 이들의 제조방법 및 이들 화합물을 함유한 방사성의약 조성물(n-alkyl peptide chelate formers, their metal complexes with radionuclides, processes for producing them and radio-pharmaceutical compositions containing these compound) |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0726909A1 (ko) |
JP (1) | JPH09508351A (ko) |
KR (1) | KR960705842A (ko) |
CN (1) | CN1134158A (ko) |
AU (1) | AU681919B2 (ko) |
CA (1) | CA2173844A1 (ko) |
DE (1) | DE4337600A1 (ko) |
HU (1) | HUT74881A (ko) |
NO (1) | NO961743L (ko) |
WO (1) | WO1995012610A1 (ko) |
ZA (1) | ZA948411B (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6241963B1 (en) * | 1995-10-19 | 2001-06-05 | The Trustees Of The University Of Pennsylvania | Dopamine and serotonin transporter ligands and imaging agents |
US6162378A (en) * | 1999-02-25 | 2000-12-19 | 3D Systems, Inc. | Method and apparatus for variably controlling the temperature in a selective deposition modeling environment |
US6171578B1 (en) | 1999-04-14 | 2001-01-09 | Diatide, Inc. | Benzodiazepine derivatives for imaging thrombi |
AU2001259691B2 (en) | 2000-05-12 | 2006-02-16 | Genzyme Corporation | Modulators of TNF-alpha signaling |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA811340B (en) * | 1980-06-09 | 1982-03-31 | Morton Norwich Products Inc | N-(cycloalkyl)amino acid compounds |
WO1992019274A1 (en) * | 1991-05-08 | 1992-11-12 | Mallinckrodt Medical, Inc. | Technetium chelates to be used for determining the renal function |
JPH0570484A (ja) * | 1991-09-12 | 1993-03-23 | Hitachi Chem Co Ltd | ペプチドおよびその塩 |
CA2129036A1 (en) * | 1992-02-06 | 1993-08-19 | Mallinckrodt Inc. | Ligands for improving metal chelate formation kinetics |
EP1004322B1 (en) * | 1992-05-21 | 2006-06-14 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
DE4311021A1 (de) * | 1993-03-31 | 1994-10-27 | Diagnostikforschung Inst | Bifunktionelle Chelatbildner, deren Technetium- und Rhenium-Komplexe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende radiopharmazeutische Mittel |
-
1993
- 1993-11-01 DE DE4337600A patent/DE4337600A1/de not_active Withdrawn
-
1994
- 1994-10-26 ZA ZA948411A patent/ZA948411B/xx unknown
- 1994-10-27 WO PCT/DE1994/001295 patent/WO1995012610A1/de not_active Application Discontinuation
- 1994-10-27 CA CA002173844A patent/CA2173844A1/en not_active Abandoned
- 1994-10-27 AU AU81038/94A patent/AU681919B2/en not_active Ceased
- 1994-10-27 JP JP7512959A patent/JPH09508351A/ja active Pending
- 1994-10-27 CN CN94193990A patent/CN1134158A/zh active Pending
- 1994-10-27 HU HU9601140A patent/HUT74881A/hu unknown
- 1994-10-27 EP EP95900059A patent/EP0726909A1/de not_active Withdrawn
-
1996
- 1996-04-30 KR KR1019960702247A patent/KR960705842A/ko not_active Application Discontinuation
- 1996-04-30 NO NO961743A patent/NO961743L/no unknown
Also Published As
Publication number | Publication date |
---|---|
CA2173844A1 (en) | 1995-05-11 |
EP0726909A1 (de) | 1996-08-21 |
ZA948411B (en) | 1995-06-30 |
AU8103894A (en) | 1995-05-23 |
JPH09508351A (ja) | 1997-08-26 |
DE4337600A1 (de) | 1995-05-04 |
NO961743D0 (no) | 1996-04-30 |
AU681919B2 (en) | 1997-09-11 |
NO961743L (no) | 1996-04-30 |
HU9601140D0 (en) | 1996-07-29 |
CN1134158A (zh) | 1996-10-23 |
HUT74881A (en) | 1997-02-28 |
WO1995012610A1 (de) | 1995-05-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |