KR960022485A - Process for preparing 3-isothiazolone salt mixture - Google Patents

Process for preparing 3-isothiazolone salt mixture Download PDF

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Publication number
KR960022485A
KR960022485A KR1019940038782A KR19940038782A KR960022485A KR 960022485 A KR960022485 A KR 960022485A KR 1019940038782 A KR1019940038782 A KR 1019940038782A KR 19940038782 A KR19940038782 A KR 19940038782A KR 960022485 A KR960022485 A KR 960022485A
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KR
South Korea
Prior art keywords
isothiazolone
preparing
salt mixture
dithiodipropionamide
dimethyl
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Application number
KR1019940038782A
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Korean (ko)
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KR100285281B1 (en
Inventor
임진수
김진만
장천희
김승환
박영
Original Assignee
김준웅
주식회사 선경인더스트리
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Priority to KR1019940038782A priority Critical patent/KR100285281B1/en
Publication of KR960022485A publication Critical patent/KR960022485A/en
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Publication of KR100285281B1 publication Critical patent/KR100285281B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2

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  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

본 발명은 3-이소티아졸론염 화합물의 제조방법에 관한 것으로서, 더욱 상세하게는 유기용매존재하에 N,N'-디메틸-3,3'-디티오디프로피온아미드, 과산화수소 및 염화수소를 반응시켜 방부제나 살균제 등과 같은 바이오사이드(biocide)로서 유용한 다음 구조식(Ⅰ)로 표시되는 2-메틸-3-이소티아졸론 염산염과 다음 구조식(Ⅱ)로 표시되는 5-클로로-2-메틸-3-이소티아졸론 염산염 혼합물을 제조하는 개선된 방법에 관한 것이다.The present invention relates to a method for preparing a 3-isothiazolone salt compound, and more particularly, by reacting N, N'-dimethyl-3,3'-dithiodipropionamide, hydrogen peroxide and hydrogen chloride in the presence of an organic solvent. 2-methyl-3-isothiazolone hydrochloride represented by the following structural formula (I) useful as a biocide, such as a bactericide, and 5-chloro-2-methyl-3-isothiazolone represented by the following structural formula (II) An improved method of preparing a hydrochloride mixture is provided.

Description

3-이소티아졸론염 혼합물의 제조방법Process for preparing 3-isothiazolone salt mixture

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (4)

용매하에서, N,N'-디메틸-3,3'-디티오디프로피온아미드와 염소기체를 반응시켜 다음 구조식(Ⅰ)로 표시되는 2-메틸-3-이소티아졸론 염산염과 다음 구조식(Ⅱ)로 표시되는 5-클로로-2-메틸-3-이소티아졸론 염산염 혼합물을 제조하는 방법에 있어서 상기 염소기체 대신에 35% 과산화수소와 35% 염산용액을 사용 하는 것을 특징으로 하는 3-이소티아졸론염 혼합물의 제조방법.In a solvent, N, N'-dimethyl-3,3'-dithiodipropionamide is reacted with chlorine gas to 2-methyl-3-isothiazolone hydrochloride represented by the following structural formula (I) and the following structural formula (II). 3-isothiazolone salt mixture, characterized in that 35% hydrogen peroxide and 35% hydrochloric acid solution are used instead of the chlorine gas in the method for preparing the 5-chloro-2-methyl-3-isothiazolone hydrochloride mixture. Manufacturing method. 제1항에 있어서, 상기 35% 과산화수소는 N,N'-디메틸-3,3'-디티오디프로피온아미드 1몰에 대하여 4∼8 몰비 사용하는 것을 특징으로 하는 3-이소티아졸론염 혼합물의 제조방법.The preparation of 3-isothiazolone salt mixture according to claim 1, wherein the 35% hydrogen peroxide is used in an amount of 4 to 8 moles per 1 mole of N, N'-dimethyl-3,3'-dithiodipropionamide. Way. 제1항에 있어서, 상기 35% 염산용액은 N,N'-디메틸-3,3'-디티오디프로피온아미드 1몰에 대하여 10∼12몰비 사용하는 것을 특징으로 하는 3-이소티아졸론염 혼합물의 제조방법.[Claim 2] The 3-isothiazolone salt mixture of claim 1, wherein the 35% hydrochloric acid solution is used in an amount of 10 to 12 moles per 1 mole of N, N'-dimethyl-3,3'-dithiodipropionamide. Manufacturing method. 제1항에 있어서, 상기 용매로는 톨루엔, 벤젠, 자일렌, 에틸아세테이트, CH2X2, CHX3, CH2XCH2X등 (여기서, X는 할로겐원소이다.)을 사용하는 특징으로 하는 3-이소티아졸론염 혼합물의 제조방법.The method of claim 1, wherein as the solvent, toluene, benzene, xylene, ethyl acetate, CH 2 X 2 , CHX 3 , CH 2 XCH 2 X, and the like, wherein X is a halogen element. Process for preparing 3-isothiazolone salt mixture. ※ 참고사항:최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019940038782A 1994-12-29 1994-12-29 Process for producing 3-isothiazolone salt mixture KR100285281B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019940038782A KR100285281B1 (en) 1994-12-29 1994-12-29 Process for producing 3-isothiazolone salt mixture

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019940038782A KR100285281B1 (en) 1994-12-29 1994-12-29 Process for producing 3-isothiazolone salt mixture

Publications (2)

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KR960022485A true KR960022485A (en) 1996-07-18
KR100285281B1 KR100285281B1 (en) 2001-04-02

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KR1019940038782A KR100285281B1 (en) 1994-12-29 1994-12-29 Process for producing 3-isothiazolone salt mixture

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100526365B1 (en) * 1999-12-27 2005-11-08 가부시키가이샤 케미크레아 Method for Producing 2-Alkyl-4-Isothiazoline-3-One

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100526365B1 (en) * 1999-12-27 2005-11-08 가부시키가이샤 케미크레아 Method for Producing 2-Alkyl-4-Isothiazoline-3-One

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KR100285281B1 (en) 2001-04-02

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