KR960015185B1 - Disposable water tissue products containing antibiosis plant extract - Google Patents

Abstract

The disposable water tissue product is made by adding more than 0.01wt% methanol or water extract of Sophora flavescens and grapefruit extract to water tissue product composed of pulp, nonwoven, etc. The product is safe for skin, and shows good prevention or suppression effects against diaper rash, redness or dermatitis.

Description

Disposable wipes containing antimicrobial plant extracts

The present invention relates to a wet tissue (wet tissue or wet wiper) products, more specifically, to hygiene products consisting of nonwoven (pulp), such as nonwoven (Sophora flavescens) and grapefruit (Grapefruit) extract by adding the hygiene The present invention relates to a wet tissue product having excellent antibacterial and antifungal properties against pathogenic microorganisms present in the skin as well as having excellent skin safety.

In the present invention, the wet tissue product is a disposable product that is used for various sanitary purposes, that is, a wet tissue product that wipes the skin when the baby discharges feces, a disposable wet towel used to keep the human body clean in a restaurant or a public place. Refers to all disposable products used for other sanitary purposes. Since these products are used directly on the skin of the human body, they should be excellent in safety for the skin, excellent in removing foreign substances and pathogenic microorganisms remaining on the skin, and excellent in antibacterial and antifungal properties.

Disposable absorbent products, which are widely used by hygiene and hygiene for babies, are decomposed by microorganisms and enzymes in the feces or skin after the product is wetted with urine or body fluid to produce ammonia, and urea decomposition products Skin irritation caused by ammonia produced by the product and chemical and physical skin irritation caused by the raw materials of the product itself are mixed, causing diaper rash, redness and dermatitis. . The root cause of diaper rash can be attributed to the hydration of the skin's stratum corneum due to the water generated during fluid excretion, continuous friction between the diaper and the skin, and secondary infection by microorganisms. Conventional wipes do not effectively prevent diaper rash, red spots and dermatitis caused by hydration of keratin, continuous rubbing of the skin and secondary infection by pathogenic microorganisms that may be caused by the use of such disposable absorbent products. There was a downside.

The present inventors have studied to solve these problems, and as a result, wet tissue products used for hygiene purposes have excellent antibacterial and antifungal properties, and ginseng used for athlete's foot, eczema, and foams and cosmetics during processing to prevent cultivation in folk medicine. When the grapefruit extract used as a preservative is added, it is a plant extract, which has little irritation than chemical synthetic fungicides, so it is very safe for the skin and has antibacterial and antifungal properties against pathogenic microorganisms on the skin. The present invention has been found to be effective in reducing diaper rash and diaper rash that may occur, as well as inhibiting or preventing diaper rash or diaper rash that may occur after diaper wear.

The present invention provides a wet tissue product comprising a ginseng and grapefruit extract in all or a part of the wet tissue product composed of nonwoven fabric, pulp and the like.

The present invention also provides a method for producing a wet tissue product, which comprises adding red ginseng and grapefruit extract in the production of nonwoven fabric and tissue or in the manufacture of wet tissue.

In the wet tissue product of the present invention, the content of red ginseng and grapefruit extract is preferably 0.01% by weight or more, preferably 1 to 20% by weight of the total weight.

Adding ginseng and grapefruit extract to conventional wet tissue products has antibacterial and antifungal effects due to its unique ingredients, inhibiting the growth of pathogenic microorganisms that act as the primary or secondary cause of diaper dermatitis and enhancing blood flow around the skin. It can rapidly induce healing of damaged areas.

Wet tissue products prepared by containing red ginseng and grapefruit extract less than 0.01% by weight of the wet tissue product were not effective at inhibiting the growth of pathogenic microorganisms in the skin, and at higher concentrations, the growth of pathogenic microorganisms in the skin Inhibitors are effective in preventing and preventing the occurrence of diaper rash and diaper dermatitis.

Therefore, when ginseng and grapefruit extract is prepared by containing 0.01 wt% or more of the total weight of the wet tissue product, it is not only excellent in inhibiting the growth of pathogenic microorganisms that are the primary or secondary cause of diaper rash and diaper rash, By promoting the blood flow of the skin by the ingredients it has an excellent effect in suppressing and preventing the damage of diaper dermatitis caused by the use of Japanese diaper. In addition, because ginseng and grapefruit extract is a plant extract, not a chemical synthetic agent, it is excellent in safety for the skin and can inhibit or prevent diaper dermatitis by the above effects and effects.

Plant extract used in the present invention (Sophora flavescens) has been used as antipyretics, diuretics, etc. from ancient times, as an external use to eradicate lice and harmful insects parasitic on the head, or eczema (eczema) or parasitic dermal lesions Is being used for healing. In addition, ginseng has been known to be effective in skin diseases such as eczema by directly stimulating the hair root (hair root) and promoting the blood flow around all of them.

Chromatography of Ginseng root extract can be divided into alkaloids eluting in water and fennel eluting substance in methanol (Table 1).

Among ginseng extracts, pharmacologically active substances are alkaloids, matrine of formula (I), oxymatrine of formula (II), sophoranol of formula (III), and formula (IV). Anagyrine).

In addition, the grapefruit used in the present invention is a kind of citrus fruits grown in the tropics and contains a large amount of citric acid and vitamin C having a strong acidity, and these two components act as a synergist to inhibit the production of nitrosoamine. It boosts immune function and affects vitamin fortification and oxidative function. Grapefruit extract is in the form of a mixture of vitamin C, amino acids, tocopherols, fatty acids, naringin, nitrogen-free compounds, etc. As a synergistic action of concentrated mixed organic matter, it has a strong bactericidal power against a wide range of harmful microorganisms such as bacteria, fungi and viruses. Grapefruit extract may be used as a preservative, such as cosmetics and processed foods.

In the present invention, the cast product of the wet tissue is a non-woven fabric, pulp, and in addition to the ginseng and grapefruit extract to the general wet tissue products using purified water, moisturizers, surfactants, pH regulators, vegetable preservatives, fragrances and the like.

In the present invention, the ginseng and grapefruit extract may be contained in the non-woven fabric and pulp of the wet tissue, or may be added in the preparation of each composition, and the wet tissue product using the non-woven fabric and pulp already containing the ginseng and grapefruit extract is also included in the present invention.

When ginseng and grapefruit extract are added to the general wet tissue products as described above, it is effective in the prevention and prevention of diaper rash and diaper rash caused by the use of disposable absorbent products by the above-mentioned action. Has action.

Hereinafter, the present invention will be described in more detail with reference to Examples and Comparative Examples.

[Comparative Example 1 and Examples 1 to 6]

Comparative Example 1 and Examples 1 to 6 were tested for antibacterial activity of ginseng and grapefruit extract, and were tested according to the standard flat method and the desoxyoxylate lactose agar medium method. The strain was used as Staphylococcus aureus, E. coli, Pseudomonas aeruginosa, which causes diaper rash and diaper rash, and Candida albicans, the most influential fungus. Inoculate bacteria at a constant concentration of 1 × 10 ⁶ / ml into sterile nutrient medium and mix 1: 1 and 1% of red ginseng and grapefruit extract, natural plant extracts, respectively 0.01%, 0.1%, 1%, 5%, 10% , And the bacterial counts were measured after 12 hours to be contained in the medium of 20% by Examples 1 to 6. Four strains, ginseng and grapefruit extracts were inoculated and cultured under conditions of 35 ± 1 ° C. and humidity of 85% or higher.

In Comparative Example 1, the number of bacteria was measured after 12 hours under the same conditions as described above, containing 1% of carton cg, which is a chemical synthetic fungicide, in a bege. After measuring the number of bacteria, the antibacterial rate was calculated by the following formula to calculate the degree of antibacterial of the ginseng and grapefruit extract.

Table 2 is a table showing the number of bacteria and the antibacterial rate per 1 ml of the medium after the above Comparative Example 1 and Examples 1 to 6.

As can be seen in Comparative Example 1 and Examples 1 to 6, the antibacterial rate was calculated by investigating the number of bacteria per 1 ml of the medium after containing ketone seed, red ginseng and grapefruit extract. Antibacterial rate was 48%, E. coli 53%, P.aeruginosa 38%, and C. albicans 55%. However, when the ginseng and grapefruit extract were contained in the medium, the antibacterial rate of S. aureus was 50%, the antibacterial rate of E. coli was 52%, the antibacterial rate of P.aeruginosa was 47%, The antimicrobial activity of C. albicans was about 38%, which was better than S.aureus and P.aeruginosa compared to ketone seed, but the effect of E. coli and C.albicans was slightly lower. The concentration should be 0.01% or more, which is expected to be excellent for each bacterium. The higher the concentration of ginseng and grapefruit, the better the antimicrobial activity. When 1-20% of ginseng and grapefruit extract were contained, the antimicrobial activity was about 58-96%.

[Comparative Examples 2 to 4 and Examples 7 to 12]

Comparative Examples 2 to 4 and Examples 7 to 12 show a therapeutic effect on diaper rash and diaper rash after using wet tissue, and are prepared by using a non-woven fabric and pulp according to a conventional wet tissue manufacturing method. 2, and Comparative Examples 3 to 4 contained the baby powder and the carton synthetic paper, which is a chemical synthetic disinfectant, in the conventional wet tissue products, respectively, in a weight ratio of the total weight of the wet tissue. And prepared by the conventional wet tissue manufacturing method by containing the ginseng and grapefruit extract in the conventional wet tissue products by 0.01%, 0.1%, 1%, 5%, 10%, 20% by weight to the total weight of the wet tissue The wet wipes product of the invention was called Examples 7-12.

Comparative Examples 2 to 4 and Examples 7 to 12 are for each 100 infants who are not suffering from diaper rash and diaper rash among 6-12 months old, when defecation is performed using a conventional disposable diaper for 24 hours, or The diaper wearing area was wiped with wet wipes prepared in Comparative Examples 2 to 4 and Examples 7 to 12 above. The wet tissues prepared from Comparative Examples 2 to 4 and Examples 7 to 12 were used five times a day for two months, and the degree of diaper rash and diaper rash was investigated.

Table 3 is a table showing the grade of the skin of the diaper wearing part by the inspector after using the wet wipes prepared from Comparative Examples 2 to 4 and Examples 7 to 12 as the fifth grade.

As can be observed in Comparative Examples 2 to 4 and Examples 7 to 12, the incidence of diaper rash and diaper skin after using the conventional wet tissue product (Comparative Example 2) was 31% (% of grade 1 or higher). Compared to Comparative Example 2, Comparative Examples 3 and 4, in which 1% each of the baby powder and the carton bacter, which is a synthetic disinfectant, were added, showed a 25% and 49% incidence, and the baby powder tended to slightly improve diaper rash and diaper rash. It was weak, but carton seed was found to weaken skin symptoms. It is believed that carton seed is a chemical synthetic fungicide that irritates the skin.

Compared with Comparative Examples 2 to 4, Examples 7 to 12, in which the ginseng and grapefruit extract were added to the conventional wet tissue product (Comparative Example 2) by concentration, showed an incidence of about 7 to 24%, and diaper rash and diaper that may appear when wearing disposable diapers. It has been shown to play a significant role in suppressing and preventing dermatitis.

The wet wipes prepared according to Examples 7 to 12 have an excellent effect on the treatment of diaper rash and chirp dermatitis, while the ginseng and grapefruit extract contained in the wet wipes removes pathogenic microorganisms on the skin and protects the skin. This is because they have improved diaper rash and diaper dermatitis.

Claims (6)

A wet tissue product composed of nonwoven fabric, pulp and the like, wherein the whole or part of its components contains red ginseng and grapefruit extract. The wet tissue product according to claim 1, wherein the ginseng and grapefruit extract contains 0.01 wt% or more of the total weight of the wet tissue product. The wet tissue product according to claim 2, wherein the wet ginseng and grapefruit extract contains 1 to 20% by weight of the total weight of the wet tissue product. The wet tissue product according to claim 1, wherein the ginseng extract is water or methanol extract extract of ginseng. The wet tissue product according to any one of claims 1 to 3, wherein the wet tissue product wipes the skin when the baby discharges the feces. The wet tissue product according to claim 1, wherein red ginseng and grapefruit extract are added at the time of manufacturing the nonwoven fabric and pulp or the wet tissue.