KR960015184B1 - Disposable absorbent articles containing antibiosis plant extract - Google Patents

Abstract

The disposable absorbent article is composed of a liquid pervious top sheet, a liquid impervious back sheet, fluff pulp and more than 0.01wt% methanol or water extract of Sophora flavescens and grapefruit extract. The product is safe for skin, and shows good prevention or suppression effects against diaper rash, redness or dermatitis. The absorbent article can be used for disposable diaper, sanitary napkin or pantyliner.

Description

Disposable absorbent products containing antimicrobial plant extracts

The present invention relates to a disposable absorbent product, and more specifically, to a conventional disposable absorbent product composed of a liquid permeable top sheet, a liquid impermeable back sheet, fluff pulp, and the like, The present invention relates to a disposable absorbent product with the addition of Sophora flavescens and Grapefruit extracts for excellent skin stability and fast healing effect against diaper rash and diaper dermatitis.

Disposable absorbent product refers to a product that absorbs body fluids excreted by various physiological actions, that is, a product that absorbs urine and feces basins, menstrual secretions and vaginal secretions. Refers to disposable diapers, sanitary napkins or pantyliners used by infants or adults. The performance of the above-mentioned disposable absorbent products is primarily evaluated by the amount of absorption and the rate of absorption of the body fluid secreted by physiological action, but in the field of absorption and absorption rate, many developments have been made by the development of super absorbent polymers. Was done. The next performance to be absorbed should be a product that can effectively prevent diaper rash and diaper dermatitis, which can be caused by the use of diapers in body fluid excretion. In addition, the diaper rash or diaper dermatitis caused by wearing a diaper should be a product having excellent healing effect of skin lesions already occurring by wearing a disposable diaper.

Disposable absorbent products consisting of conventional liquid permeable top sheets, downy pulp and liquid impermeable back sheets are product diuretic or wetted with body fluids, after which urea in the urine is decomposed by microorganisms and enzymes present in feces or skin, producing ammonia, There was a problem that the skin marks by ammonia produced as a urea decomposition product and chemical and physical skin irritation by the raw material of the product itself combined to cause diaper rash, red spots and skin inflammation. The root cause of diaper rash can be attributed to the hydration of the skin's stratum corneum due to the water generated during fluid excretion, continuous friction between the diaper and the skin, and secondary infection by microorganisms.

Korean Patent Laid-Open Nos. 86-8743 and 86-8744 propose to change the pH by using an inorganic acid or by containing an acid functional residue, but it is not effective in terms of skin safety. On the other hand, it is known to treat with a fungicide synthesized by a chemical synthesis method, but in order to prevent skin rashes, a significant amount of the fungicide is required to carry out the skin fungus that is present on the skin and directly or indirectly affects the skin. The irritation of the added synthetic fungicides can cause further problems.

Therefore, the present inventors have studied to solve all the problems of the prior art, the antimicrobial and antifungal properties of disposable absorbent products consisting of liquid permeable top sheet, liquid impermeable back sheet, down pulp, etc. To prevent the addition of Sophora flavescens, which is used for athlete's foot, eczema, and Grapefruit extract, which is used as a preservative for processed foods and cosmetics, it is a plant extract with almost no irritation than chemical synthetic fungicides. The present invention has been found to have antimicrobial and antifungal properties against pathogenic microorganisms on the skin and to effectively reduce diaper rash and diaper rash, as well as to inhibit or prevent diaper rash or diaper rash that may occur after wearing diapers. This Reotda.

The present invention provides a disposable absorbent article comprising a red ginseng extract and grapefruit extract in all or part of its components in a disposable absorbent article composed of a liquid permeable topsheet, a liquid impermeable backsheet, down pulp, and the like. .

The present invention also provides a method for producing a disposable absorbent article, comprising adding red ginseng and grapefruit extract to a part which is easy to contact with the skin during the production of a liquid permeable top sheet, a coagulated band and down pulp or a disposable diaper. do.

The content of red ginseng and grapefruit extract in the disposable absorbent article of the present invention is preferably 0.01% by weight or more, preferably 1-20% by weight of the total weight.

The addition of high ginseng grapefruit extract to conventional disposable absorbent products has antibacterial and antifungal effects due to the unique ingredients of ginseng, inhibiting the growth of pathogenic microorganisms that act as the primary or secondary cause of diaper dermatitis and reducing blood flow around the skin. By promoting it, it is possible to rapidly induce the healing of the skin injury site. In addition, the antibacterial grapefruit extract with strong antimicrobial activity can inhibit diaper dermatitis and diaper rash by disinfecting pathogenic microorganisms on the skin area, and the pH of the grapefruit extract is about 3, which can greatly alleviate the symptoms of diaper rash and diaper rash.

Disposable products prepared by containing ginseng and grapefruit extract less than 0.01% of the total weight of the disposable absorbent product were not effective at inhibiting the growth of pathogenic microorganisms in the skin, and at higher concentrations, the growth of pathogenic microorganisms on the skin It is effective in suppressing and preventing and preventing the occurrence of diaper rash and diaper rash. Therefore, when the ginseng is prepared by containing 0.01% or more of the total weight of the disposable absorbent product, it is also excellent in absorbing and removing body fluids and inhibiting the growth of pathogenic microorganisms that are the primary or secondary cause of diaper rash and diaper rash. The special ingredients of red ginseng and grapefruit itself have an excellent effect on healing the damage caused by diaper dermatitis by promoting blood flow of the skin and preventing alkalinity of the skin. In addition, because ginseng and grapefruit extract is a plant extract, not a chemical synthetic agent, it is excellent in the stability on the skin and has little toxicity on the skin, and can inhibit or prevent diaper dermatitis by the above effects and effects.

The ginseng plant extract used in the present invention has been used as an antipyretic, diuretic, etc. since ancient times, and for external use, it is known to have lice and harmful insects parasitic on the head, or to heal eczema or parasitic dermal lesions. It is used. In addition, ginseng has a function of promoting hair growth by directly stimulating the hair root and promoting blood flow around the hair root, and has been known to be effective in skin diseases such as eczema.

Chromatography of the ginseng root extract with water and ethanol solvent can be represented by alkaloids eluting in water and phenolic substances eluting in methanol (Table 1).

Among ginseng extracts, pharmacologically active substances are alkaloids, matrine of formula (I), oxymatrine of formula (II), sophoranol of formula (III), and formula (Ⅳ). Anagyrine).

In addition, grapefruit used in the present invention is a kind of citrus fruits grown in the tropics and contains a large amount of citric acid and vitamin C having a strong acidity, and these two components act as a synergist, restraining the production of nitrosoamine and immunity. Increasing function, while affecting vitamin lowering and oxidative function. Grapefruit extract is a form of a mixture of vitamin C, amino acids, tocopherols, fatty acids, naringin, nitrogen-free compounds, etc. As a synergistic action of concentrated mixed organic matter has a strong bactericidal power against a wide range of harmful microorganisms, such as bacteria, fungi, viruses. Grapefruit extract may be a preservative such as cosmetics and processed foods.

The liquid permeable top sheet in the present invention is known for use in conventional disposable absorbent articles, and the most commonly used liquid permeable top sheet is nonwoven. Downy pulp is made of wood by processing wood pulp and is a hydrophilic absorbent material that absorbs secretions and is used in conventional disposable absorbent products. Liquid impermeable bowel sheets are also used in conventional disposable absorbent products, and generally used non-breathable waterproof film, breathable waterproof film, and biodegradable waterproof film, and the non-woven fabric is laminated to such liquid impermeable backsheet. Can also be used.

The present invention uses a conventional liquid permeable top sheet, a fluffy pulp and a liquid impermeable back sheet which are used in conventional disposable absorbent articles as castings, and in addition to tissues, adhesive tapes or fixings as auxiliary compositions. Normally using optional systems such as buttons, frontal tape, thigh or waist elastics, barrier cuffs, leg standing cuffs, adhesives (hot melt, glue, etc.), and systems for fastening to underwear such as panties It is to add red ginseng and grapefruit extract to the disposable absorbent product.

As a method of adding the ginseng and grapefruit extract used in the present invention to conventional disposable absorbent products, there are the following methods.

(1) Method to contain in liquid permeable top sheet

(2) Method to make into fluffy pulp

(3) Method to contain in barrier cuff

(4) Method to contain in tissue

(5) Method to contain at the time of manufacture of disposable absorbent product

The method of the above (1) to (5) refers to the addition of red ginseng and grapefruit extract in the preparation of each composition, and more specifically, the liquid permeable top sheet, the downy pulp, the coagulation band, the superabsorbency, which already contains the mixture. Disposable absorbent articles using resins or tissues are also included in the present invention.

Addition of ginseng and grapefruit extract, which are common plant extracts of disposable absorbent products as described above, inhibits the growth and proliferation of pathogenic fungi that cause the first and second causes of diaper rash or diaper rash and pathogenic bacteria that cause secondary infection. It accelerates the healing of eczema and dermatitis, and helps to reduce the normal skin. Also, as a plant extract, it is very safe for the skin and has an effective effect on the prevention and prevention of diaper rash and diaper dermatitis.

Hereinafter, the present invention will be described in more detail with reference to Examples and Comparative Examples.

[Comparative Examples 1 and 2 and Examples 1 to 12]

Comparative Examples 1 to 2 and Examples 1 to 12 were tested for the antibacterial properties of ginseng and grapefruit extract, and were tested according to the standard plate method and the desoxyoxylate lactose agar medium method. The strains used were Staphylococcus aureus, E. coli, Pseudomonas aeruginosa, which causes diaper rash and diaper rash, and Candida albicans, the most influential fungus. Inoculate bacteria at a constant concentration of 1 × 10 ⁶ / ml into a sterile nutrient medium and mix 1: 1 and 1% of red ginseng and grapefruit extract, natural plant extracts, respectively 0.01%, 0.1%, 1%, 5%, 10% , And the bacterial count was measured after 6 hours to be contained in the medium by 20%, and the bacterial count was measured after 12 hours as Examples 7 to 12. Four strains and ginseng were inoculated and cultured under conditions of 35 ± 1 ° C. and humidity of 85% or higher.

In Comparative Examples 1 and 2, 1% of the chemical synthetic bactericide Katon CG was contained in the medium, and the number of bacteria was measured after 6 hours and 12 hours under the same conditions as described above. After measuring the number of bacteria, the antibacterial rate was calculated by the following formula to calculate the antimicrobial activity of Gosam and grapefruit extract.

Table 2 is a table showing the number of bacteria and the antibacterial rate per 1 ml of the medium after the above Comparative Examples 1 to 2 and Examples 1 to 12.

As shown in Comparative Examples 1 to 2 and Examples 1 to 12, the antibacterial rate was calculated by investigating the number of bacteria per 1 ml of the medium after containing ketone seed, red ginseng and grapefruit extract. The antibacterial rate of aureus was 48-50%, the antibacterial rate of E. coli was 55-57%, the antibacterial rate of Paeruginosa was 38-53%, and the antibacterial rate of C. albicans was 55-57%, respectively. There was no difference between and after 12 hours. However, when the ginseng and grapefruit extract were mixed in 1: 1 and contained in the medium, there was no difference in the antibacterial rate after 6 hours and 12 hours, but E. coli and S when 0.01% of ginseng and grapefruit extract were included in the medium. The antimicrobial activity was about 20% only for aureus, so the concentration of red ginseng and grapefruit extract should be 0.01% or higher. The higher the concentration of plant extracts, the better the antimicrobial activity. When 1-20% of ginseng and grapefruit extract were contained, the antimicrobial activity of each bacterium was about 48-96%.

[Comparative Examples 3 to 5 and Examples 13 to 18]

Comparative Examples 3 to 5 and Examples 13 to 18 show skin protection effects against diaper rash and diaper rash that may occur when disposable diapers are worn, and are usually composed of a liquid permeable top sheet, a fluffy pulp, and a liquid impermeable back sheet. The conventional disposable diaper product manufactured according to the disposable diaper manufacturing method of was referred to as Comparative Example 3. In the conventional disposable diaper composition, red ginseng and grapefruit extract are mixed in a ratio of 1: 1 to 0.01%, 0.1%, 1%, 5%, 10%, and 20%, respectively, in the liquid permeable top sheet in the weight ratio to the weight of the disposable diaper. The disposable diaper product of the present invention manufactured according to the conventional disposable diaper manufacturing method was called Examples 13 to 18.

In Comparative Examples 4 to 5, baby powder and a chemical synthetic disinfectant, carton CG, which are currently commercially available in conventional disposable diaper products, were added to the liquid permeable top sheet at a weight ratio of the total weight of disposable diapers. It was prepared according to a conventional disposable diaper manufacturing method.

In Comparative Examples 3 to 5 and Examples 13 to 18, 100 infants aged 3 to 10 months were directly used for 1 month to examine the degree of diaper rash and diaper rash.

Table 3 is a table that distinguishes the skin symptoms of the diaper wearing area by 5 grades after using the disposable diapers prepared from Comparative Examples 3 to 5 and Examples 13 to 18 for 1 month for 24 hours.

As can be seen in Comparative Examples 3 to 5 and Examples 13 to 18, in the conventional disposable diaper product (Comparative Example 3), the ratio of skin grade 0 was about 32%, and compared to Comparative Example 3, baby powder and ketone seed paper At 41% and 27%, respectively, baby powder had a weak skin protection effect, while ketone seed, a chemical synthetic fungicide, was rather irritating to the skin.

Examples 13 to 18 in which ginseng and grapefruit extract were added to conventional disposable diaper products (Comparative Example 5) by concentrations compared to Comparative Examples 3 to 4 may have a 0-skin ratio of 52 to 71%, which may appear when wearing disposable diapers. It has been shown to be excellent in preventing diaper rash and diaper dermatitis. Disposable diapers prepared according to Examples 13 to 18 exhibited excellent effects on the prevention of diaper rash and diaper rash, and skin sensation such as S. aureus and C. albicans, where red ginseng and grapefruit extracts were on the skin, causing diaper rash. This is because it inhibits the growth of bacteria and at the same time helps to heal skin lesions caused by diaper rash. It is also thought to alleviate the symptoms of diaper rash and diaper rash by preventing skin alkalinization by urine.

Claims (6)

A disposable absorbent product composed of a liquid permeable topsheet, a liquid impermeable backsheet, fluffy pulp, and the like, wherein all or part of its components contain ginseng and grapefruit extract. The disposable absorbent article of claim 1, wherein the ginseng and grapefruit extract contains 0.01 wt% or more of the total weight of the disposable absorbent article. 3. The disposable absorbent product of Claim 2 comprising 1-20% by weight of ginseng and grapefruit extract in the total weight of the disposable absorbent product. The disposable absorbent article of claim 1, wherein the ginseng extract is water or methanol extract extract of ginseng. The product as claimed in claim 1, wherein the disposable absorbent product is a diaper, a sanitary napkin or a pantyliner. The disposable absorbent article according to claim 1, wherein red ginseng and grapefruit extract are added to a portion which is easy to contact with skin in the manufacture of a liquid permeable topsheet, a liquid impermeable backsheet, and a fluffy pulp or in the manufacture of a disposable diaper.