KR950704322A - 스피로푸라논 유도체 및 그의 신경변성 질환 치료 용도(Spirofuranone Derivatives and Their Use in the Treatment of Neurodegenerative Disorders) - Google Patents

스피로푸라논 유도체 및 그의 신경변성 질환 치료 용도(Spirofuranone Derivatives and Their Use in the Treatment of Neurodegenerative Disorders)

Info

Publication number
KR950704322A
KR950704322A KR1019950702268A KR19950702268A KR950704322A KR 950704322 A KR950704322 A KR 950704322A KR 1019950702268 A KR1019950702268 A KR 1019950702268A KR 19950702268 A KR19950702268 A KR 19950702268A KR 950704322 A KR950704322 A KR 950704322A
Authority
KR
South Korea
Prior art keywords
alkyl
compound
formula
pharmaceutically acceptable
optionally substituted
Prior art date
Application number
KR1019950702268A
Other languages
English (en)
Korean (ko)
Inventor
알렉산더 코버
제임스 3세 로크
죠지 뮬렌
에드윈 쉔-쵸우 우
Original Assignee
로버트 고든 맥레어 라이트
피존스 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929225498A external-priority patent/GB9225498D0/en
Priority claimed from GB929225497A external-priority patent/GB9225497D0/en
Priority claimed from GB939316531A external-priority patent/GB9316531D0/en
Application filed by 로버트 고든 맥레어 라이트, 피존스 코포레이션 filed Critical 로버트 고든 맥레어 라이트
Publication of KR950704322A publication Critical patent/KR950704322A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019950702268A 1992-12-05 1993-12-06 스피로푸라논 유도체 및 그의 신경변성 질환 치료 용도(Spirofuranone Derivatives and Their Use in the Treatment of Neurodegenerative Disorders) KR950704322A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB9225498.6 1992-12-05
GB929225498A GB9225498D0 (en) 1992-12-05 1992-12-05 Pharmacologically active compounds
GB929225497A GB9225497D0 (en) 1992-12-05 1992-12-05 Pharmacologically active compounds
GB9225497.8 1992-12-05
GB9316531.4 1993-08-10
GB939316531A GB9316531D0 (en) 1993-08-10 1993-08-10 Pharmacologically active compounds
PCT/GB1993/002500 WO1994013678A1 (en) 1992-12-05 1993-12-06 Spirofuranone derivatives and their use in the treatment of neurodegenerative disorders

Publications (1)

Publication Number Publication Date
KR950704322A true KR950704322A (ko) 1995-11-17

Family

ID=27266497

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950702268A KR950704322A (ko) 1992-12-05 1993-12-06 스피로푸라논 유도체 및 그의 신경변성 질환 치료 용도(Spirofuranone Derivatives and Their Use in the Treatment of Neurodegenerative Disorders)

Country Status (10)

Country Link
EP (1) EP0672046A1 (no)
JP (1) JPH08503955A (no)
KR (1) KR950704322A (no)
AU (1) AU5655394A (no)
CA (1) CA2150947A1 (no)
FI (1) FI952733A0 (no)
IL (1) IL107881A0 (no)
MX (1) MX9307679A (no)
NO (1) NO952194L (no)
WO (1) WO1994013678A1 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2270884A1 (en) * 1997-01-27 1998-07-30 Haile Tecle Single pot process for producing (z)-azabicyclo oxime ethers
TWI243173B (en) 1999-11-17 2005-11-11 Akzo Nobel Nv Spiro[2H-1-benzopyran-2,4'-piperidine] derivatives
KR100783836B1 (ko) 2004-01-08 2007-12-10 에프. 호프만-라 로슈 아게 글라이신 트랜스포터 1 및 글라이신 트랜스포터 2의억제제로서의 다이아자-스피로피페리딘 유도체

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075317A (en) * 1989-06-21 1991-12-24 Fisons Corporation Spirofurane derivatives
JPH03153690A (ja) * 1989-11-10 1991-07-01 Yamanouchi Pharmaceut Co Ltd ヘテロ環スピロ誘導体及びその製造法
IE914238A1 (en) * 1990-12-19 1992-07-01 Fisons Corp Novel spirofurane derivatives

Also Published As

Publication number Publication date
FI952733A (fi) 1995-06-05
FI952733A0 (fi) 1995-06-05
IL107881A0 (en) 1994-04-12
EP0672046A1 (en) 1995-09-20
JPH08503955A (ja) 1996-04-30
CA2150947A1 (en) 1994-06-23
AU5655394A (en) 1994-07-04
NO952194D0 (no) 1995-06-02
MX9307679A (es) 1994-06-30
NO952194L (no) 1995-06-02
WO1994013678A1 (en) 1994-06-23

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