KR950703347A - 이노시톨 1,4,5-트리포스페이트의 길항 방법(Method for Antagonizing Inositol 1,4,5-Triphosphate) - Google Patents
이노시톨 1,4,5-트리포스페이트의 길항 방법(Method for Antagonizing Inositol 1,4,5-Triphosphate) Download PDFInfo
- Publication number
- KR950703347A KR950703347A KR1019950701166A KR19950701166A KR950703347A KR 950703347 A KR950703347 A KR 950703347A KR 1019950701166 A KR1019950701166 A KR 1019950701166A KR 19950701166 A KR19950701166 A KR 19950701166A KR 950703347 A KR950703347 A KR 950703347A
- Authority
- KR
- South Korea
- Prior art keywords
- inositol
- triphosphate
- antagonizing
- oligomers
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- MMWCIQZXVOZEGG-HOZKJCLWSA-N [(1S,2R,3S,4S,5R,6S)-2,3,5-trihydroxy-4,6-diphosphonooxycyclohexyl] dihydrogen phosphate Chemical compound O[C@H]1[C@@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]1OP(O)(O)=O MMWCIQZXVOZEGG-HOZKJCLWSA-N 0.000 title claims abstract 4
- 230000003042 antagnostic effect Effects 0.000 title 1
- 230000000694 effects Effects 0.000 claims abstract 2
- 230000002401 inhibitory effect Effects 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/795—Polymers containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyurethanes Or Polyureas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95239392A | 1992-09-28 | 1992-09-28 | |
| US07/952393 | 1992-09-28 | ||
| PCT/US1993/008168 WO1994007507A1 (en) | 1992-09-28 | 1993-08-30 | Method for antagonizing inositol 1,4,5-triphosphate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR950703347A true KR950703347A (ko) | 1995-09-20 |
Family
ID=25492868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019950701166A Ceased KR950703347A (ko) | 1992-09-28 | 1993-08-30 | 이노시톨 1,4,5-트리포스페이트의 길항 방법(Method for Antagonizing Inositol 1,4,5-Triphosphate) |
Country Status (13)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2978995A (en) * | 1994-06-30 | 1996-01-25 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Methods for treating cell proliferative disorders by modulating signal transduction |
| US5780483A (en) * | 1995-02-17 | 1998-07-14 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| JPH11503110A (ja) | 1995-02-17 | 1999-03-23 | スミスクライン・ビーチャム・コーポレイション | Ｉｌ−８受容体拮抗剤 |
| US6083920A (en) * | 1995-12-21 | 2000-07-04 | Ayurcore, Inc. | Compositions for modulating intracellular inositol trisphosphate concentration |
| US6005008A (en) * | 1996-02-16 | 1999-12-21 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| US6262113B1 (en) | 1996-03-20 | 2001-07-17 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| US6211373B1 (en) | 1996-03-20 | 2001-04-03 | Smithkline Beecham Corporation | Phenyl urea antagonists of the IL-8 receptor |
| TR199802694T2 (xx) * | 1996-06-27 | 1999-03-22 | Smithkline Beecham Corporation | IL-8 resept�r kar��tlar� |
| PL330849A1 (en) | 1996-06-27 | 1999-06-07 | Smithkline Beecham Corp | Antagonists of il-8 receptors |
| CA2427757A1 (en) * | 2000-11-09 | 2002-05-16 | Contrimmune Biotechnology Inc. | Therapeutic uses for ip3 receptor-mediated calcium channel modulators |
| WO2013033657A2 (en) | 2011-09-02 | 2013-03-07 | The Trustees Of Columbia University In The City Of New York | CaMKII, IP3R, CALCINEURIN, P38 AND MK2/3 INHIBITORS TO TREAT METABOLIC DISTURBANCES OF OBESITY |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB781479A (en) * | 1953-08-27 | 1957-08-21 | Ciba Ltd | New polyureas and process for making them |
| US5276182A (en) * | 1990-07-09 | 1994-01-04 | The Dow Chemical Company | Process for preparing polyurea oligomers |
-
1993
- 1993-08-30 NZ NZ256178A patent/NZ256178A/en unknown
- 1993-08-30 AU AU48417/93A patent/AU670962B2/en not_active Ceased
- 1993-08-30 JP JP6509054A patent/JPH08502068A/ja active Pending
- 1993-08-30 EP EP93921252A patent/EP0661982A1/en not_active Ceased
- 1993-08-30 CA CA002145681A patent/CA2145681A1/en not_active Abandoned
- 1993-08-30 WO PCT/US1993/008168 patent/WO1994007507A1/en not_active Application Discontinuation
- 1993-08-30 KR KR1019950701166A patent/KR950703347A/ko not_active Ceased
- 1993-08-30 HU HU9500891A patent/HUT70192A/hu unknown
- 1993-09-21 ZA ZA936978A patent/ZA936978B/xx unknown
- 1993-09-22 TW TW082107787A patent/TW260663B/zh active
- 1993-09-22 IL IL107066A patent/IL107066A/en not_active IP Right Cessation
- 1993-09-27 MX MX9305933A patent/MX9305933A/es unknown
-
1995
- 1995-03-27 NO NO951163A patent/NO951163L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO951163D0 (no) | 1995-03-27 |
| NO951163L (no) | 1995-03-27 |
| IL107066A0 (en) | 1993-12-28 |
| EP0661982A1 (en) | 1995-07-12 |
| IL107066A (en) | 1998-01-04 |
| HU9500891D0 (en) | 1995-05-29 |
| AU670962B2 (en) | 1996-08-08 |
| NZ256178A (en) | 1997-03-24 |
| CA2145681A1 (en) | 1994-04-14 |
| TW260663B (enrdf_load_stackoverflow) | 1995-10-21 |
| MX9305933A (es) | 1994-04-29 |
| ZA936978B (en) | 1994-04-18 |
| WO1994007507A1 (en) | 1994-04-14 |
| HUT70192A (en) | 1995-09-28 |
| JPH08502068A (ja) | 1996-03-05 |
| AU4841793A (en) | 1994-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 19950327 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19951020 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19980616 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 19980827 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 19980616 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |