KR950031085A - 표피증식 질환 치료용 의약 조성물 - Google Patents

표피증식 질환 치료용 의약 조성물 Download PDF

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Publication number
KR950031085A
KR950031085A KR1019950008911A KR19950008911A KR950031085A KR 950031085 A KR950031085 A KR 950031085A KR 1019950008911 A KR1019950008911 A KR 1019950008911A KR 19950008911 A KR19950008911 A KR 19950008911A KR 950031085 A KR950031085 A KR 950031085A
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South Korea
Prior art keywords
pharmaceutical composition
acceptable salt
pharmacologically acceptable
treatment
compound
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KR1019950008911A
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English (en)
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가즈미 오가다
다까히로 사까우에
사찌꼬 마쓰우라
리에 나가오
신야 오기노
Original Assignee
요시다 쇼오지
센쥬 세이야꾸 가부시기가이샤
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Application filed by 요시다 쇼오지, 센쥬 세이야꾸 가부시기가이샤 filed Critical 요시다 쇼오지
Publication of KR950031085A publication Critical patent/KR950031085A/ko

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/665Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

아래의 구조식의 안산 디에스테르 화합물 또는 약리학적으로 허용되는 그 염을 함유하는 표피 증식 치료용 의약 조성물.
위의 식에서 R1과 R2는 같거나 상이하며 각각 수소 원자 또는 메틸기를 나타낸다.
본 발명의 조성물은 건선(乾癬), 어린선(魚鱗蘚), 손바닥 또는 발바닥 각피증 및 모공성 홍색 비강진(pityriasis rubra pillaris)등의 표피 증식 질환의 치료제로 유용하다.

Description

표피증식 질환 치료용 의약 조성물.
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
보통의 건선이 있는 마우스 모델에서의 시간 경과에 따른 귀의 팽윤율을 나타내는 그래프.

Claims (6)

  1. 아래의 구조식의 인산 디에스테르 화합물 또는 약리학적으로 허용되는 그 염을 함유하는 표피 증식 치료용 의약 조성물.
    위의 식에서 R1과 R2는 같거나 상이하며 각각 수소 원자 또는 메틸기를 나타낸다.
  2. 제1항에 있어서, 국소 적용용의 의약 조성물.
  3. 제2항에 있어서, 연고제, 액제 또는 겔제인 국소 적용용의 의약 조성물.
  4. 제3항에 있어서, 상기 화합물 또는 약리학적으로 허용되는 염의 상기 연고제 또는 겔제중에서의 농도가 0.01∼5(w/w)%인 의약 조성물.
  5. 제3항에 있어서, 상기 화합물 또는 약리학적으로 허용되는 염의 상기 액제중에서의농도가 0.01∼5(w/w)%인 의약 조성물.
  6. 아래의 구조식의 인산 디에스테르 화합물 또는 약리학적으로 허용되는 그 염을 함유하는 의약 조성물의 유효량을 표피 증식 질환을 가진 환자에게 투여하는 표피 증식 질환 치료방법.
    위의 식에서 R1과 R2는 같거나 상이하며 각각 수소 원자 또는 메틸기를 나타낸다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950008911A 1994-04-22 1995-04-15 표피증식 질환 치료용 의약 조성물 KR950031085A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8424894 1994-04-22
JP94-84248 1994-04-22

Publications (1)

Publication Number Publication Date
KR950031085A true KR950031085A (ko) 1995-12-18

Family

ID=13825166

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950008911A KR950031085A (ko) 1994-04-22 1995-04-15 표피증식 질환 치료용 의약 조성물

Country Status (6)

Country Link
EP (1) EP0679399B1 (ko)
KR (1) KR950031085A (ko)
AT (1) ATE156359T1 (ko)
DE (1) DE69500511T2 (ko)
ES (1) ES2107279T3 (ko)
TW (1) TW287103B (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2209690A1 (en) * 1996-07-31 1998-01-31 Sachiko Matsuura Therapeutic drug for acne vulgaris
WO2002026238A1 (en) * 2000-09-26 2002-04-04 Vital Health Sciences Pty Ltd. Phosphate derivative supplements
AUPR549901A0 (en) 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
CN1547475B (zh) * 2001-07-27 2010-12-15 生命健康科学有限公司 含电子转移试剂的磷酸酯衍生物的皮肤制剂
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
US6645514B1 (en) 2002-12-19 2003-11-11 Access Business Group International, Llc Increasing skin cell renewal with water-soluble Vitamin E
ATE495730T1 (de) 2004-03-03 2011-02-15 Vital Health Sciences Pty Ltd Alkaloid-formulierungen
MX2007015949A (es) * 2005-06-17 2008-03-07 Vital Health Sciences Pty Ltd Un vehiculo que comprende uno o mas derivados de fosfato de di- y/o mono-(agentes de transferencia de electrones) o complejos de los mismos.
KR20080085839A (ko) * 2005-12-23 2008-09-24 바이탈 헬스 사이언시즈 피티와이 리미티드 사이토킨 조절 특성을 가진 화합물
EP2531047A4 (en) 2010-02-05 2014-03-19 Phosphagenics Ltd CARRIER WITH AN UNINUTRALIZED TOCOPHERYL PHOSPHATE
CA2794734C (en) 2010-03-30 2017-12-12 Phosphagenics Limited Transdermal delivery patch
US9561243B2 (en) 2011-03-15 2017-02-07 Phosphagenics Limited Composition comprising non-neutralised tocol phosphate and a vitamin A compound
CN108601732A (zh) 2015-12-09 2018-09-28 磷肌酸有限公司 药物制剂
WO2018112512A1 (en) 2016-12-21 2018-06-28 Phosphagenics Limited Process

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5659710A (en) * 1979-10-22 1981-05-23 Eisai Co Ltd Preventive and remedy for psoriasis
JPS62145019A (ja) * 1985-12-19 1987-06-29 Senjiyu Seiyaku Kk 抗炎症剤
US5122536A (en) * 1989-10-12 1992-06-16 Perricone Nicholas V Method for the topical treatment of psoriasis

Also Published As

Publication number Publication date
DE69500511T2 (de) 1998-01-02
EP0679399B1 (en) 1997-08-06
ES2107279T3 (es) 1997-11-16
TW287103B (ko) 1996-10-01
EP0679399A1 (en) 1995-11-02
ATE156359T1 (de) 1997-08-15
DE69500511D1 (de) 1997-09-11

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