KR950008509A - 인돌릴알킬-피리디닐 및 피리미디닐피페파라진의 항편두통 사이클로부텐디온 유도체 - Google Patents
인돌릴알킬-피리디닐 및 피리미디닐피페파라진의 항편두통 사이클로부텐디온 유도체 Download PDFInfo
- Publication number
- KR950008509A KR950008509A KR1019940023922A KR19940023922A KR950008509A KR 950008509 A KR950008509 A KR 950008509A KR 1019940023922 A KR1019940023922 A KR 1019940023922A KR 19940023922 A KR19940023922 A KR 19940023922A KR 950008509 A KR950008509 A KR 950008509A
- Authority
- KR
- South Korea
- Prior art keywords
- piperazinyl
- propyl
- methoxy
- indole
- dioxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12226693A | 1993-09-16 | 1993-09-16 | |
| US08/122,266 | 1993-09-16 | ||
| US08/277,789 US5521188A (en) | 1993-09-16 | 1994-07-25 | Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines |
| US08/277,789 | 1994-07-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR950008509A true KR950008509A (ko) | 1995-04-17 |
Family
ID=22401677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019940023922A Ceased KR950008509A (ko) | 1993-09-16 | 1994-09-16 | 인돌릴알킬-피리디닐 및 피리미디닐피페파라진의 항편두통 사이클로부텐디온 유도체 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5521188A (https=) |
| KR (1) | KR950008509A (https=) |
| TW (1) | TW310325B (https=) |
| ZA (1) | ZA946201B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE374192T1 (de) * | 2000-11-29 | 2007-10-15 | Lilly Co Eli | 1-(2-m-methansulfonamidophenylethyl)-4-(m- trifluoromethylphenyl)piperazine und ihre akzeptablen pharmazeutischen salze und solvate und ihre verwendung zur behandlung von inkontinenz |
| KR100752035B1 (ko) * | 2001-07-27 | 2007-08-28 | 주식회사유한양행 | 3-사이클로부텐-1,2-다이온 유도체 및 그의 제조방법 |
| WO2015014256A1 (en) | 2013-07-29 | 2015-02-05 | Sunshine Lake Pharma Co., Ltd. | Substituted heteroaryl compounds and methods of use thereof |
| US10316025B2 (en) | 2015-06-03 | 2019-06-11 | Sunshine Lake Pharma Co., Ltd. | Substituted piperazine compounds and methods of use and use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3468882A (en) * | 1966-10-07 | 1969-09-23 | Sterling Drug Inc | Phenylhydrazone derivatives as intermediates for preparing indoles |
| GB8924373D0 (en) * | 1989-10-30 | 1989-12-20 | Beecham Group Plc | Novel compounds |
| US5077293A (en) * | 1990-06-29 | 1991-12-31 | Bristol-Myers Squibb Co. | 1-indolyalkyl-4-(alkoxypyrimidinyl)piperazines |
| CA2043709C (en) * | 1990-06-29 | 2002-01-22 | David W. Smith | Antimigraine alkoxypyrimidine derivatives |
| CA2084531A1 (en) * | 1991-12-19 | 1993-06-20 | David W. Smith | Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines |
| NZ254112A (en) * | 1992-07-10 | 1997-06-24 | Boots Co Plc | Dioxocyclobutene derivatives; compounds, preparation and pharmaceutical compositions |
-
1994
- 1994-07-25 US US08/277,789 patent/US5521188A/en not_active Expired - Fee Related
- 1994-08-17 TW TW083107556A patent/TW310325B/zh active
- 1994-08-17 ZA ZA946201A patent/ZA946201B/xx unknown
- 1994-09-16 KR KR1019940023922A patent/KR950008509A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US5521188A (en) | 1996-05-28 |
| ZA946201B (en) | 1995-03-31 |
| TW310325B (https=) | 1997-07-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19940916 |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19990916 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19940916 Comment text: Patent Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20011123 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20020220 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20011123 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |