KR950005303A - 진균 감염 치료 방법(method of treating fungal infections) - Google Patents

진균 감염 치료 방법(method of treating fungal infections) Download PDF

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Publication number
KR950005303A
KR950005303A KR1019940020742A KR19940020742A KR950005303A KR 950005303 A KR950005303 A KR 950005303A KR 1019940020742 A KR1019940020742 A KR 1019940020742A KR 19940020742 A KR19940020742 A KR 19940020742A KR 950005303 A KR950005303 A KR 950005303A
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KR
South Korea
Prior art keywords
antimicrobial
fungal
compound
fungal cells
fungal infections
Prior art date
Application number
KR1019940020742A
Other languages
English (en)
Inventor
브라운 피어리 로버트
루터 스카트루드 폴
Original Assignee
피터 지. 스트링거
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 피터 지. 스트링거, 일라이 릴리 앤드 캄파니 filed Critical 피터 지. 스트링거
Publication of KR950005303A publication Critical patent/KR950005303A/ko

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/475Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

특히, 본 발명은 상승제와 결합하여 항균제를 투여하므로써 항균제에 대한 진균 세포의 민감성을 증가시키는 방법을 제공한다. 본 발명은 항균 화합물의 활성을 상승시키는 제제의 능력에 대한 시험 방법을 또한 제공한다.

Description

진균 감염 치료 방법(METHOD OF TREATING FUNGAL INFECTIONS)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. (ⅰ) 항균제 및 (ⅱ) 상승제 각각의 효과량을 진균 세포에 투여함을 포함하는, 항균제에 대한 상기 진균 세포의 민감성을 증가시키는 방법.
  2. (ⅰ) 항균제 및 (ⅱ) 상승제; 및 약학적으로 허용가능한 부형제 각각의 효과량을 포함하는 약학 제제.
  3. 제2항에 있어서, 진균 감염 치료용 약학 제제.
  4. (a) (ⅰ) 진균 세포가 내성을 갖는 항균 화합물 및 (ⅱ) 항균-상승 특성을 갖는 것으로 예상되는 화합물의 존재하에 상기 진균 세포의 배양물을 성장시키고, (b) 상기 화합물의 항균제에 대한 항균-상승 효과를 측정함을 포함하는 상기 진균 세포에 노출된 항균제에서 화합물의 항균-상승 효과를 측정하기 위한 분석 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019940020742A 1993-08-25 1994-08-23 진균 감염 치료 방법(method of treating fungal infections) KR950005303A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11168093A 1993-08-25 1993-08-25
US8/111,680 1993-08-25

Publications (1)

Publication Number Publication Date
KR950005303A true KR950005303A (ko) 1995-03-20

Family

ID=22339881

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940020742A KR950005303A (ko) 1993-08-25 1994-08-23 진균 감염 치료 방법(method of treating fungal infections)

Country Status (12)

Country Link
EP (1) EP0643971A3 (ko)
JP (1) JPH07149663A (ko)
KR (1) KR950005303A (ko)
CN (1) CN1110605A (ko)
AU (1) AU7028394A (ko)
CA (1) CA2130025A1 (ko)
CZ (1) CZ204294A3 (ko)
HU (1) HUT69996A (ko)
IL (1) IL110699A (ko)
NO (1) NO943129L (ko)
NZ (1) NZ264294A (ko)
ZA (1) ZA946444B (ko)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057493A (en) * 1988-07-19 1991-10-15 Takara Shuzo Co., Ltd. Novel antibiotics r106
DE69206007T2 (de) * 1991-02-19 1996-07-25 Takara Shuzo Co Fungizide für den Acker- und Gartenbau.
JPH07502274A (ja) * 1991-12-10 1995-03-09 ラシユ−プレスビタリアン−セントルークス・メデイカル・センター 多薬剤耐性を低下させる方法および組成物

Also Published As

Publication number Publication date
NO943129D0 (no) 1994-08-24
AU7028394A (en) 1995-03-09
NZ264294A (en) 1997-05-26
EP0643971A3 (en) 1996-05-29
CZ204294A3 (en) 1995-12-13
IL110699A0 (en) 1994-11-11
IL110699A (en) 1999-06-20
CA2130025A1 (en) 1995-02-26
JPH07149663A (ja) 1995-06-13
NO943129L (no) 1995-02-27
HU9402433D0 (en) 1994-10-28
CN1110605A (zh) 1995-10-25
ZA946444B (en) 1996-02-26
HUT69996A (en) 1995-09-28
EP0643971A2 (en) 1995-03-22

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