KR940703666A - 발기 부전증 치료에 효능있는 약제(a potent drug for treatment of erectile dysfunction) - Google Patents

발기 부전증 치료에 효능있는 약제(a potent drug for treatment of erectile dysfunction)

Info

Publication number
KR940703666A
KR940703666A KR1019940702181A KR19940702181A KR940703666A KR 940703666 A KR940703666 A KR 940703666A KR 1019940702181 A KR1019940702181 A KR 1019940702181A KR 19940702181 A KR19940702181 A KR 19940702181A KR 940703666 A KR940703666 A KR 940703666A
Authority
KR
South Korea
Prior art keywords
compound
erectile dysfunction
treatment
potent drug
formula
Prior art date
Application number
KR1019940702181A
Other languages
English (en)
Inventor
이. 불 알렌
Original Assignee
로렌스 티. 웰츠
디 업존 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 로렌스 티. 웰츠, 디 업존 캄파니 filed Critical 로렌스 티. 웰츠
Publication of KR940703666A publication Critical patent/KR940703666A/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

음경에 소량의 피리딜구아니딘 화합물, 바람직하게는 N-시아노-N'-(1,1-디메틸 프로필)-N"-(3-피리디닐)구아니딘을 투여하므로써 발기를 유도 또는 증진시키거나 또는 발진 부전증을 치료하기 위한 방법, DMARUD 해면체로내로의 주사 또는 경피적 적용에 의해 투여할 수 있다.

Description

발기 부전증 치료에 효능있는 약제(A POTENT DRUG FOR TREATMENT OF ERECTILE DYSFUNCTION)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 포유동물에서 발기를 유도하거나 또는 증진시키는데 유용한 약물을 제조하기 위한, 하기 일반식(Ⅰ)의 화합물 또는 그의 약학적으로 허용가능한 염의 용도.
    상기식에서, R1및 R2는 독립적으로 수소, 또는 C1-8알킬, C2-8알켄, C3-8사이클로알킬 및 그의 이성체 형태이다.
  2. 제1항에 있어서, 일반식(Ⅰ)의 화합물을 음경 해면체내에 주사하는 용도.
  3. 제1항에 있어서, 일반식(Ⅰ)의 화합물이 N-시아노-N'-(1,1-디메틸프로필)-N"-(3-피리디닐)구아니던 또는 그의 약학적으로 허용가능한 염인 용도.
  4. 제2항에 있어서, 인간에서 0.5㎍ 내지 1000㎍의 양으로 주사하는 용도.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019940702181A 1991-12-23 1992-12-02 발기 부전증 치료에 효능있는 약제(a potent drug for treatment of erectile dysfunction) KR940703666A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81670091A 1991-12-23 1991-12-23
US07816700 1991-12-23
PCT/US1992/010254 WO1993012788A1 (en) 1991-12-23 1992-12-02 Pyridylguanidine compounds for treatment of erectile dysfunction

Publications (1)

Publication Number Publication Date
KR940703666A true KR940703666A (ko) 1994-12-12

Family

ID=25221384

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940702181A KR940703666A (ko) 1991-12-23 1992-12-02 발기 부전증 치료에 효능있는 약제(a potent drug for treatment of erectile dysfunction)

Country Status (12)

Country Link
US (1) US5488059A (ko)
EP (1) EP0618798B1 (ko)
JP (1) JPH07506333A (ko)
KR (1) KR940703666A (ko)
AT (1) ATE149834T1 (ko)
AU (1) AU661747B2 (ko)
CA (1) CA2123312A1 (ko)
DE (1) DE69218246T2 (ko)
DK (1) DK0618798T3 (ko)
ES (1) ES2099293T3 (ko)
GR (1) GR3023448T3 (ko)
WO (1) WO1993012788A1 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6007836A (en) * 1993-05-28 1999-12-28 Vericade, Inc. Transdermal vasodilator
US5741511A (en) * 1995-04-12 1998-04-21 Sam Yang Co., Ltd. Transdermal drug delivery device for treating erectile dysfunction
US5952006A (en) * 1995-09-29 1999-09-14 L.A.M. Pharmaceuticals, Llc Drug preparations for treating impotency
US6063405A (en) * 1995-09-29 2000-05-16 L.A.M. Pharmaceuticals, Llc Sustained release delivery system
US6036977A (en) * 1995-09-29 2000-03-14 L.A.M. Pharmaceutical Corp. Drug preparations for treating sexual dysfunction
US5942545A (en) * 1998-06-15 1999-08-24 Macrochem Corporation Composition and method for treating penile erectile dysfunction
US6417207B1 (en) 1999-05-12 2002-07-09 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
US6436944B1 (en) * 1999-09-30 2002-08-20 Pfizer Inc. Combination effective for the treatment of impotence
KR20010076961A (ko) * 2000-01-29 2001-08-17 김제종 성기능장애 예방 및 치료용 약제
WO2007022964A2 (de) 2005-08-24 2007-03-01 Abbott Gmbh & Co. Kg Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1489879A (en) * 1974-12-20 1977-10-26 Leo Pharm Prod Ltd N'-cyano-n'-3-pyridylguanidines
US4127118B1 (en) * 1977-03-16 1995-12-19 Alvaro Latorre Method of effecting and enhancing an erection
US4521421A (en) * 1983-09-26 1985-06-04 Eli Lilly And Company Treatment of sexual dysfunction
US4801587A (en) * 1987-03-02 1989-01-31 Gene Voss Impotence ointment

Also Published As

Publication number Publication date
CA2123312A1 (en) 1993-07-08
AU3149793A (en) 1993-07-28
GR3023448T3 (en) 1997-08-29
ES2099293T3 (es) 1997-05-16
DE69218246T2 (de) 1997-07-17
DE69218246D1 (de) 1997-04-17
DK0618798T3 (da) 1997-09-22
EP0618798B1 (en) 1997-03-12
JPH07506333A (ja) 1995-07-13
EP0618798A1 (en) 1994-10-12
AU661747B2 (en) 1995-08-03
ATE149834T1 (de) 1997-03-15
WO1993012788A1 (en) 1993-07-08
US5488059A (en) 1996-01-30

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