KR940014773A - Microorganisms That Produce Cephalosporin C and Methods of Making Cephalosporin C Using the Same - Google Patents

Microorganisms That Produce Cephalosporin C and Methods of Making Cephalosporin C Using the Same Download PDF

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Publication number
KR940014773A
KR940014773A KR1019920027566A KR920027566A KR940014773A KR 940014773 A KR940014773 A KR 940014773A KR 1019920027566 A KR1019920027566 A KR 1019920027566A KR 920027566 A KR920027566 A KR 920027566A KR 940014773 A KR940014773 A KR 940014773A
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South Korea
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cephalosporin
kfcc
microorganisms
making
methods
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KR1019920027566A
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Korean (ko)
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KR960004035B1 (en
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길광훈
손영선
유명규
이근철
박종성
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김정순
제일제당 주식회사
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

본 발명은 세팔로스포리움 아크레모니움 KFCC 10679로부터 메티오닌의 유사체인 D, L-셀레노메티오닌에 내성을 가지며 배지에서 첨가하는 메티오닌의 농도가 낮은 상태에서도 세팔로스포린C를 고농도로 생산하며서 친주에 비해 배양액의 점도가 매우 낮은 세팔로스포린C 생산 돌연변이주 KFCC 10782을 획득하여 이성화액당, 혼합오일, 콘스팁리커, 땅콩분 등이 함유된 배지중에서 배양하여 배양물로부터 세팔로스포린C를 채취하는 것을 특징으로 한다.The present invention is resistant to methionine analogues D and L-selenomethionine from cephalosporium acremonium KFCC 10679 and produces cephalosporin C at high concentration even in low concentrations of methionine added in the medium. To obtain a cephalosporin C from the culture by obtaining a cephalosporin C producing mutant strain KFCC 10782, which has a very low viscosity of the culture, and culturing in a medium containing isomerized sugar, mixed oil, corn steep liquor, and peanut powder. It features.

Description

세팔로스포린 C를 생산하는 미생물 및 이를 이용한 세팔로스포린C 의 제조방법.Microorganisms producing cephalosporin C and a method for producing cephalosporin C using the same.

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (2)

메티오닌 유사체인 D,L-셀레노메티오닌의 농도가 7ug/ml이상인 조건에서도 생육이 가능하고 배양액의 점도가 낮은 세팔로스포린 c를 생산하는 미생물 세팔로스포리움 아크레모니움 CRC 0901 (KFCC 10782).Microbial cephalosporium acremonium CRC 0901 (KFCC 10782), which is capable of growing under conditions of D, L-selenomethionine, a methionine analogue, of 7 μg / ml or higher and producing cephalosporin c with low viscosity. 제1항의 세팔로스포리움 아크레모니움 CRC 0901 (KFCC 10782)을 이성화액당, 혼합오일, 땅콩분, 콘스팁리커 등이 함유된 배지에서 배양하여 세펠로스포린 C를 체취하는 것을 특징으로 하는 세팔로스포린 C의 제조방법.The cephalosporin C is characterized by culturing the cephalosporium acremonium CRC 0901 (KFCC 10782) in a medium containing isomerized sugar, mixed oil, peanut powder, corn steep liquor and the like. Preparation of Sporin C. ※참고사항:최초출원 내용에 의하여 공개하는 것임.※ Note: This is to be disclosed based on the first application.
KR1019920027566A 1992-12-31 1992-12-31 Microorganism that produces cephalos porin c, and the processing method of cephalosporin c with using it KR960004035B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019920027566A KR960004035B1 (en) 1992-12-31 1992-12-31 Microorganism that produces cephalos porin c, and the processing method of cephalosporin c with using it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019920027566A KR960004035B1 (en) 1992-12-31 1992-12-31 Microorganism that produces cephalos porin c, and the processing method of cephalosporin c with using it

Publications (2)

Publication Number Publication Date
KR940014773A true KR940014773A (en) 1994-07-19
KR960004035B1 KR960004035B1 (en) 1996-03-25

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KR1019920027566A KR960004035B1 (en) 1992-12-31 1992-12-31 Microorganism that produces cephalos porin c, and the processing method of cephalosporin c with using it

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KR960004035B1 (en) 1996-03-25

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