KR960023039A - Microorganisms That Produce Sepharosporin C and Methods of Preparing Sepharosporin C Using the Same - Google Patents

Microorganisms That Produce Sepharosporin C and Methods of Preparing Sepharosporin C Using the Same Download PDF

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Publication number
KR960023039A
KR960023039A KR1019940033568A KR19940033568A KR960023039A KR 960023039 A KR960023039 A KR 960023039A KR 1019940033568 A KR1019940033568 A KR 1019940033568A KR 19940033568 A KR19940033568 A KR 19940033568A KR 960023039 A KR960023039 A KR 960023039A
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South Korea
Prior art keywords
sepharosporin
producing
acremonium
cephalosporin
same
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Application number
KR1019940033568A
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Korean (ko)
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KR0134131B1 (en
Inventor
길광훈
손영선
이근철
박종성
정연준
김해균
고중환
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김정순
제일제당 주식회사
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Priority to KR1019940033568A priority Critical patent/KR0134131B1/en
Publication of KR960023039A publication Critical patent/KR960023039A/en
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Publication of KR0134131B1 publication Critical patent/KR0134131B1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/745—Cephalosporium ; Acremonium
    • C12R2001/75—Cephalosporium acremonium ; Acremonium strictum

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

본 발명은 세파로스포린 C를 생산하는 미생물 및 이를 이용한 세파로스포린 C의 제조방법에 관한 것이다. 구체적으로, 본 발명의 미생물 세파로스포리움 아크레모니움 KFCC-10845은 세파로스포리움 아크레모니움 KFCC10782의 변이주로서 호흡억제제인 포타슘시아나이드에 내성을 가지며 친주에 비해 산소 요구성이 낮고 고농도로 세파로스포린 C를 생산하며 이를 이성화액당, 혼합오일, 땅콩분 등이 함유된 배지중에서 배양하여 세파로스포린 C를 고농도로 생산시키는 제조방법에 관한 것이다.The present invention relates to a microorganism producing cephalosporin C, and to a method for producing cephalosporin C using the same. Specifically, the microorganism Sepharoseporium acremonium KFCC-10845 of the present invention is a mutant of Sepharoseporium acremonium KFCC10782, which is resistant to potassium cyanide, a respiratory inhibitor, and has a low oxygen demand and a high concentration of cepa. The present invention relates to a production method for producing high concentrations of cephalosporin C by producing Rosporin C and culturing it in a medium containing isomerized sugar, mixed oil, peanut powder, and the like.

Description

세파로스포린 C를 생산하는 미생물 및 이를 이용한 세파로스포린 C의 제조방법Microorganisms That Produce Sepharosporin C and Methods of Preparing Sepharosporin C Using the Same

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (2)

호흡억제제인 포타슘시아나이드의 농도가 10μg/ml 이상인 조건에서 생육할 수 있고 산소 요구성이 낮은미생물로 세파로스포린 C를 생산하는 세파로스포리움 아크레모니움 KFCC-10845.Separosporium acremonium KFCC-10845, which produces cephalosporin C as a microorganism with low oxygen demand, which can grow under conditions of potassium cyanide, a respiratory inhibitor, of 10 μg / ml or more. 세파로스포리움 아크레모니움 KFCC-10845을 배양하여 세파로스포린 C를 제조하는 방법.Method for preparing Sepharosporin C by culturing Sepharoseporium acremonium KFCC-10845. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019940033568A 1994-12-06 1994-12-06 Cephalosporium which produces cephalosporin and process for cephalosporin KR0134131B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019940033568A KR0134131B1 (en) 1994-12-06 1994-12-06 Cephalosporium which produces cephalosporin and process for cephalosporin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019940033568A KR0134131B1 (en) 1994-12-06 1994-12-06 Cephalosporium which produces cephalosporin and process for cephalosporin

Publications (2)

Publication Number Publication Date
KR960023039A true KR960023039A (en) 1996-07-18
KR0134131B1 KR0134131B1 (en) 1998-04-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940033568A KR0134131B1 (en) 1994-12-06 1994-12-06 Cephalosporium which produces cephalosporin and process for cephalosporin

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111850078A (en) * 2020-07-21 2020-10-30 伊犁川宁生物技术有限公司 Fermentation method of cephalosporin C

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100446108B1 (en) * 1997-10-24 2004-10-26 씨제이 주식회사 Cephalosporin c-producing microorganism having improved lipase activity and method for producing cephalosporin c using the same
KR100446110B1 (en) * 1997-10-24 2004-10-28 씨제이 주식회사 Cephalosporin c-producing microorganism having tolerance against high concentration of glycerol

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111850078A (en) * 2020-07-21 2020-10-30 伊犁川宁生物技术有限公司 Fermentation method of cephalosporin C

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Publication number Publication date
KR0134131B1 (en) 1998-04-14

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