KR940003291B1 - 1,5-벤조티아제핀 유도체, 그의 제조 방법 및 심장혈관 질환의 치료시 용도 - Google Patents

1,5-벤조티아제핀 유도체, 그의 제조 방법 및 심장혈관 질환의 치료시 용도 Download PDF

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Publication number
KR940003291B1
KR940003291B1 KR1019890010523A KR890010523A KR940003291B1 KR 940003291 B1 KR940003291 B1 KR 940003291B1 KR 1019890010523 A KR1019890010523 A KR 1019890010523A KR 890010523 A KR890010523 A KR 890010523A KR 940003291 B1 KR940003291 B1 KR 940003291B1
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KR
South Korea
Prior art keywords
group
methoxyphenyl
dihydro
dimethylaminoethyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019890010523A
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English (en)
Korean (ko)
Other versions
KR910002821A (ko
Inventor
히로아끼 야나기사와
고이찌 후지모또
야스오 시모지
다꾸로 가나자끼
히로유끼 고이께
히로시 니시노
Original Assignee
상꾜 가부시끼가이샤
가와무라 요시부미
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 상꾜 가부시끼가이샤, 가와무라 요시부미 filed Critical 상꾜 가부시끼가이샤
Publication of KR910002821A publication Critical patent/KR910002821A/ko
Application granted granted Critical
Publication of KR940003291B1 publication Critical patent/KR940003291B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
KR1019890010523A 1988-07-25 1989-07-25 1,5-벤조티아제핀 유도체, 그의 제조 방법 및 심장혈관 질환의 치료시 용도 Expired - Fee Related KR940003291B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP185097/88 1988-07-25
JP18509788 1988-07-25
JP267540/88 1988-10-24
JP26754088 1988-10-24
JP41024/89 1989-02-21
JP4102489 1989-02-21

Publications (2)

Publication Number Publication Date
KR910002821A KR910002821A (ko) 1991-02-26
KR940003291B1 true KR940003291B1 (ko) 1994-04-20

Family

ID=27290681

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890010523A Expired - Fee Related KR940003291B1 (ko) 1988-07-25 1989-07-25 1,5-벤조티아제핀 유도체, 그의 제조 방법 및 심장혈관 질환의 치료시 용도

Country Status (8)

Country Link
US (1) US5002942A (OSRAM)
EP (1) EP0353032B1 (OSRAM)
KR (1) KR940003291B1 (OSRAM)
CA (1) CA1336712C (OSRAM)
DE (1) DE68900867D1 (OSRAM)
ES (1) ES2034642T3 (OSRAM)
GR (1) GR3004725T3 (OSRAM)
IE (1) IE62994B1 (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1255545B (it) * 1992-10-23 1995-11-09 Procedimento per la preparazione di diltiazem
ATE167858T1 (de) * 1994-09-16 1998-07-15 Orion Corp Fermion Verfahren zur herstellung von pharmazeutisch aktiven benzothiazepinderivaten.
FI97725C (fi) * 1995-02-17 1997-02-10 Orion Yhtymae Oy Menetelmä diltiatseemin valmistamiseksi
US5709897A (en) * 1995-09-12 1998-01-20 Pearlstein; Leonard Absorbent packaging for food products
JP4875561B2 (ja) * 2007-07-20 2012-02-15 株式会社クボタ 作業車のサスペンション構造
EP2330895A4 (en) * 2008-08-22 2013-07-31 Milestone Pharmaceuticals Inc BENZOTHIAZEPINE CALCIUM CHANNEL BLOCKER WITH SHORT EFFECT AND ITS USE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55167282A (en) * 1979-06-12 1980-12-26 Fujisawa Pharmaceut Co Ltd Piperazine derivative or its salt and its preparation
DE3064910D1 (en) * 1979-06-12 1983-10-27 Fujisawa Pharmaceutical Co 2-oxo-benzothiazoline, benzoxazoline or indoline derivatives, their preparation, and pharmaceutical compositions comprising such derivatives
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
US4590188A (en) * 1984-02-18 1986-05-20 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and their pharmaceutical use
US4594342A (en) * 1984-04-10 1986-06-10 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivative

Also Published As

Publication number Publication date
EP0353032B1 (en) 1992-02-26
KR910002821A (ko) 1991-02-26
EP0353032A1 (en) 1990-01-31
IE892409L (en) 1990-01-25
ES2034642T3 (es) 1993-04-01
IE62994B1 (en) 1995-03-08
US5002942A (en) 1991-03-26
CA1336712C (en) 1995-08-15
GR3004725T3 (OSRAM) 1993-04-28
DE68900867D1 (de) 1992-04-02

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