KR930005870B1 - 디데옥시아데노신의 효소적 탈아민화에 의한 디데옥시이노신의 제조방법 - Google Patents

디데옥시아데노신의 효소적 탈아민화에 의한 디데옥시이노신의 제조방법 Download PDF

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Publication number
KR930005870B1
KR930005870B1 KR1019880008865A KR880008865A KR930005870B1 KR 930005870 B1 KR930005870 B1 KR 930005870B1 KR 1019880008865 A KR1019880008865 A KR 1019880008865A KR 880008865 A KR880008865 A KR 880008865A KR 930005870 B1 KR930005870 B1 KR 930005870B1
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KR
South Korea
Prior art keywords
group
dideoxyinosine
protecting group
structural formula
hydroxy protecting
Prior art date
Application number
KR1019880008865A
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English (en)
Korean (ko)
Other versions
KR900001858A (ko
Inventor
파리나 빗토리오
에이. 베니그니 다니엘
알. 브로드퓨어러 폴
Original Assignee
브리스톨-마이어즈 스퀴브 컴페니
아이삭 자아코브스키
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 브리스톨-마이어즈 스퀴브 컴페니, 아이삭 자아코브스키 filed Critical 브리스톨-마이어즈 스퀴브 컴페니
Publication of KR900001858A publication Critical patent/KR900001858A/ko
Application granted granted Critical
Publication of KR930005870B1 publication Critical patent/KR930005870B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019880008865A 1987-07-17 1988-07-15 디데옥시아데노신의 효소적 탈아민화에 의한 디데옥시이노신의 제조방법 KR930005870B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7484487A 1987-07-17 1987-07-17
US74,844 1987-07-17
US074,844 1987-07-17

Publications (2)

Publication Number Publication Date
KR900001858A KR900001858A (ko) 1990-02-27
KR930005870B1 true KR930005870B1 (ko) 1993-06-25

Family

ID=22122017

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880008865A KR930005870B1 (ko) 1987-07-17 1988-07-15 디데옥시아데노신의 효소적 탈아민화에 의한 디데옥시이노신의 제조방법

Country Status (8)

Country Link
KR (1) KR930005870B1 (de)
AT (1) AT395977B (de)
CA (1) CA1335187C (de)
ES (1) ES2007532A6 (de)
FI (1) FI92602C (de)
GR (1) GR1000483B (de)
LU (1) LU87280A1 (de)
PT (1) PT88017B (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0206497B1 (de) * 1985-05-15 1994-07-20 The Wellcome Foundation Limited Therapeutische Nucleoside und deren Herstellung
IL85778A0 (en) * 1987-03-20 1988-09-30 Bristol Myers Co Production of 2',3'-dideoxynucleosides and certain such novel compounds

Also Published As

Publication number Publication date
GR1000483B (el) 1992-07-30
GR880100455A (en) 1989-04-12
ES2007532A6 (es) 1989-06-16
FI92602B (fi) 1994-08-31
PT88017A (pt) 1989-06-30
FI92602C (fi) 1994-12-12
FI883339A (fi) 1989-01-18
AT395977B (de) 1993-04-26
CA1335187C (en) 1995-04-11
KR900001858A (ko) 1990-02-27
ATA173088A (de) 1992-09-15
PT88017B (pt) 1995-03-01
FI883339A0 (fi) 1988-07-13
LU87280A1 (fr) 1989-03-08

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