KR920702235A - 모든-시스-1,3,5-트리아미노-2,4,6-시클로헥산트리올 및 그 유도체와 방사능 금속이온의 착물에 대한 방사능 진단 목적과 종양치료를 위한 용도 및 방사능 진단 목적용과 종양치료용 시약의 제조를 위한 용도 - Google Patents

모든-시스-1,3,5-트리아미노-2,4,6-시클로헥산트리올 및 그 유도체와 방사능 금속이온의 착물에 대한 방사능 진단 목적과 종양치료를 위한 용도 및 방사능 진단 목적용과 종양치료용 시약의 제조를 위한 용도

Info

Publication number
KR920702235A
KR920702235A KR1019920701057A KR920701057A KR920702235A KR 920702235 A KR920702235 A KR 920702235A KR 1019920701057 A KR1019920701057 A KR 1019920701057A KR 920701057 A KR920701057 A KR 920701057A KR 920702235 A KR920702235 A KR 920702235A
Authority
KR
South Korea
Prior art keywords
alkyl group
use according
formula
radioactive metal
iib
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019920701057A
Other languages
English (en)
Korean (ko)
Inventor
에르니 이시도르
쉬나이더 발터
헤크게츠쉬바일러 카스파르
가이서 페터
Original Assignee
원본미기재
라보라토리엔 하우스만 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본미기재, 라보라토리엔 하우스만 아게 filed Critical 원본미기재
Publication of KR920702235A publication Critical patent/KR920702235A/ko
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019920701057A 1990-09-05 1991-09-05 모든-시스-1,3,5-트리아미노-2,4,6-시클로헥산트리올 및 그 유도체와 방사능 금속이온의 착물에 대한 방사능 진단 목적과 종양치료를 위한 용도 및 방사능 진단 목적용과 종양치료용 시약의 제조를 위한 용도 Ceased KR920702235A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP40281396 1990-09-05
DE4028139A DE4028139A1 (de) 1990-09-05 1990-09-05 Verwendung der komplexe radioaktiver metallionen mit all-cis-1,3,5-triamino-2,4,6-cyclohexantriol und seinen derivaten fuer roentgendiagnostische zwecke und in der tumortherapie sowie zur herstellung von mitteln fuer roentgendiagnostische zwecke und fuer die tumortherapie
PCT/EP1991/001679 WO1992004056A1 (de) 1990-09-05 1991-09-05 VERWENDUNG DER KOMPLEXE RADIOAKTIVER METALLIONEN MIT all-cis-1,3,5-TRIAMINO-2,4,6-CYCLOHEXANTRIOL UND SEINEN DERIVATEN FÜR RÖNTGENDIAGNOSTISCHE ZWECKE UND IN DER TUMORTHERAPIE SOWIE ZUR HERSTELLUNG VON MITTELN FÜR RÖNTGENDIAGNOSTISCHE ZWECKE UND FÜR DIE TUMORTHERAPIE

Publications (1)

Publication Number Publication Date
KR920702235A true KR920702235A (ko) 1992-09-03

Family

ID=6413642

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920701057A Ceased KR920702235A (ko) 1990-09-05 1991-09-05 모든-시스-1,3,5-트리아미노-2,4,6-시클로헥산트리올 및 그 유도체와 방사능 금속이온의 착물에 대한 방사능 진단 목적과 종양치료를 위한 용도 및 방사능 진단 목적용과 종양치료용 시약의 제조를 위한 용도

Country Status (10)

Country Link
EP (1) EP0504339A1 (enExample)
JP (1) JPH05502456A (enExample)
KR (1) KR920702235A (enExample)
AU (1) AU658148B2 (enExample)
CA (1) CA2073050A1 (enExample)
DE (1) DE4028139A1 (enExample)
MX (1) MX9100967A (enExample)
PT (1) PT98869A (enExample)
TW (1) TW197951B (enExample)
WO (1) WO1992004056A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830430A (en) 1995-02-21 1998-11-03 Imarx Pharmaceutical Corp. Cationic lipids and the use thereof
EP2849804A1 (en) * 2012-05-18 2015-03-25 Bayer Pharma Aktiengesellschaft Bis azainositol heavy metal complexes for x-ray imaging
EP2796152A1 (en) 2013-04-25 2014-10-29 Bayer Pharma Aktiengesellschaft Unsymmetrical Bis Azainositol Hafnium Complexes for X-Ray Imaging
EP2873670A1 (en) 2013-11-14 2015-05-20 Bayer Pharma Aktiengesellschaft Bis azainositol zirconium complexes for X-ray imaging

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3503614A1 (de) * 1985-02-02 1986-08-07 Laboratorien Hausmann AG, St. Gallen All-cis-1,3,5-triamino-2,4,6-cyclohexantriol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate
GB8900719D0 (en) * 1989-01-13 1989-03-08 Nycomed As Compounds
CH679742A5 (enExample) * 1990-01-09 1992-04-15 Byk Gulden Lomberg Chem Fab

Also Published As

Publication number Publication date
AU8436791A (en) 1992-03-30
WO1992004056A1 (de) 1992-03-19
JPH05502456A (ja) 1993-04-28
CA2073050A1 (en) 1992-03-06
DE4028139A1 (de) 1992-03-12
EP0504339A1 (de) 1992-09-23
MX9100967A (es) 1992-05-04
PT98869A (pt) 1992-07-31
TW197951B (enExample) 1993-01-11
AU658148B2 (en) 1995-04-06

Similar Documents

Publication Publication Date Title
US4419339A (en) Formulation and method of making cationic lipophilic complexes
KR880012572A (ko) 질소함유 고리형 배위자의 제조방법
Cooper Crown thio ether chemistry
JPH04506955A (ja) 窒素含有マクロ環状リガンド及びそれらの金属複合体
AU587637B2 (en) Carboxy,carboalkoxy and carbamyl substituted isonitrile radionuclide complexes
AU690562B2 (en) Tri(platinum) complexes
Schmidbaur et al. Beryllium salicylate dihydrate
KR920702235A (ko) 모든-시스-1,3,5-트리아미노-2,4,6-시클로헥산트리올 및 그 유도체와 방사능 금속이온의 착물에 대한 방사능 진단 목적과 종양치료를 위한 용도 및 방사능 진단 목적용과 종양치료용 시약의 제조를 위한 용도
Cramer et al. Crystal and molecular structure and isotropic hydrogen-1 nuclear magnetic resonance shifts of hexakis (acetic acid) nickel (II) tetrafluoroborate [Ni (AcOH) 6](BF4) 2
EP0472665B1 (en) 99m tc(iii) myocardial imaging agents that are effective in humans
Holm et al. Nontemplate synthesis of an unsaturated tetraaza [14] macrocycle and its metal (II) complexes
KR960706467A (ko) 아릴 할라이드 치환된 금속 착물, 이를 함유하는 약제, 진단상의 그의 용도 및 이 착물 및 약제의 제조 방법(Aryl Halide Substituted Metallic Complexes, Pharmaceuticals Containing These Complexes, Their Use for Diagnostic Purposes, and Methods for Preparing the Complexes and Pharmaceuticals)
ES421067A1 (es) Procedimiento para la preparacion de nuevas 2-fenilamino- imidazolinas sustituidas.
KR860000871A (ko) 방사성 핵종의 부위강화 진달성 화합물 및 그 사용법
US4872561A (en) Carboxy, carboalkoxy and carbamile substituted isonitrile radionuclide complexes
US4921944A (en) Method of pharmaceutic production
EP0419538A4 (en) Technetium (iii/ii) imaging agents
KR890701139A (ko) Tc-99m 방사성의약품의 제조
US4582698A (en) Process for imaging cardiac infarcts
KR930007964A (ko) 저 산소 국재화 잔기를 함유하는 레늄 및 테크네륨 착물
KR870000935A (ko) 신규의 방사성 약 화합물 및 이 약화합물 제조용 킬레이트제
ES394980A1 (es) Un procedimiento para la preparacion de nuevos benzopira- nos.
PL147612B1 (en) Method of obtaining a pharmaceutic with affinity to neoplastic tissues
DE59009184D1 (de) Myokardgängige Technetium-Komplexverbindungen und Verfahren zu deren Herstellung.
ES360862A1 (es) Procedimiento para la preparacion de nuevos derivados de tiazepina.

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19920504

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19960905

Comment text: Request for Examination of Application

Patent event code: PA02011R01I

Patent event date: 19920504

Comment text: Patent Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19981027

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 19990118

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 19981027

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I