KR920019783A - 인돌 및 디하이드로 퀴놀린 칼륨 채널 개방제 - Google Patents

인돌 및 디하이드로 퀴놀린 칼륨 채널 개방제 Download PDF

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Publication number
KR920019783A
KR920019783A KR1019920006186A KR920006186A KR920019783A KR 920019783 A KR920019783 A KR 920019783A KR 1019920006186 A KR1019920006186 A KR 1019920006186A KR 920006186 A KR920006186 A KR 920006186A KR 920019783 A KR920019783 A KR 920019783A
Authority
KR
South Korea
Prior art keywords
alkyl
hydrogen
cycloalkyl
haloalkyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019920006186A
Other languages
English (en)
Korean (ko)
Inventor
애트월 카네일
씨. 로브니악 조오지
Original Assignee
니콜라스 피. 말라테스티닉
이이. 아르. 스퀴브 앤드 산즈, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 니콜라스 피. 말라테스티닉, 이이. 아르. 스퀴브 앤드 산즈, 인크. filed Critical 니콜라스 피. 말라테스티닉
Publication of KR920019783A publication Critical patent/KR920019783A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019920006186A 1991-04-15 1992-04-14 인돌 및 디하이드로 퀴놀린 칼륨 채널 개방제 Withdrawn KR920019783A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68532391A 1991-04-15 1991-04-15
US7/685,323 1991-04-15
US07/760,030 US5310932A (en) 1991-04-15 1991-09-11 Chromanyl substituted indole potassium channel openers
US760030 1991-09-11

Publications (1)

Publication Number Publication Date
KR920019783A true KR920019783A (ko) 1992-11-20

Family

ID=24751693

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920006186A Withdrawn KR920019783A (ko) 1991-04-15 1992-04-14 인돌 및 디하이드로 퀴놀린 칼륨 채널 개방제

Country Status (5)

Country Link
US (1) US5310932A (enExample)
KR (1) KR920019783A (enExample)
IE (1) IE920926A1 (enExample)
TW (1) TW264474B (enExample)
ZA (1) ZA922113B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US6083986A (en) * 1996-07-26 2000-07-04 Icagen, Inc. Potassium channel inhibitors
US6333337B1 (en) 1998-01-27 2001-12-25 Icagen, Inc. Potassium channel inhibitors
EP1240147A1 (en) * 1999-12-21 2002-09-18 Icagen, Inc. Potassium channel inhibitors
US6566380B2 (en) * 2000-07-25 2003-05-20 Icagen, Inc. Potassium channel inhibitors
US6620849B2 (en) 2000-07-26 2003-09-16 Icafen, Inc. Potassium channel inhibitors
KR100389127B1 (ko) * 2000-10-09 2003-06-25 동부한농화학 주식회사 벤조피라닐 헤테로고리 유도체, 그의 제조방법 및 그를포함하는 약학적 조성물
US6849634B2 (en) 2000-12-21 2005-02-01 Icagen Potassium channel inhibitors
ATE543813T1 (de) * 2005-09-01 2012-02-15 Janssen Pharmaceutica Nv Neue benzopyranderivate als kaliumkanalöffner
US7812183B2 (en) * 2005-09-01 2010-10-12 Janssen Pharmaceutica Nv Benzopyran derivatives as potassium channel openers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0205292B1 (en) * 1985-06-08 1991-11-06 Beecham Group Plc Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them
GB8521857D0 (en) * 1985-09-03 1985-10-09 Beecham Group Plc Active compounds
GB8613786D0 (en) * 1986-06-06 1986-07-09 Beecham Group Plc Active compounds
GB8625185D0 (en) * 1986-10-21 1986-11-26 Beecham Group Plc Active compounds
IL88035A0 (en) * 1987-10-27 1989-06-30 American Home Prod Benzopyran derivatives,their preparation and pharmaceutical compositions containing them
US4988723A (en) * 1988-06-02 1991-01-29 Fujisawa Pharmaceutical Co., Ltd. Benzopyran derivatives and their use as anti-hypertensives

Also Published As

Publication number Publication date
US5310932A (en) 1994-05-10
TW264474B (enExample) 1995-12-01
IE920926A1 (en) 1992-10-21
ZA922113B (en) 1992-11-25

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19920414

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid