KR910016759A - Benzoxazine derivatives and preparation method thereof - Google Patents

Benzoxazine derivatives and preparation method thereof Download PDF

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Publication number
KR910016759A
KR910016759A KR1019900004181A KR900004181A KR910016759A KR 910016759 A KR910016759 A KR 910016759A KR 1019900004181 A KR1019900004181 A KR 1019900004181A KR 900004181 A KR900004181 A KR 900004181A KR 910016759 A KR910016759 A KR 910016759A
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KR
South Korea
Prior art keywords
structural formula
following structural
lower alkyl
benzoxazine
derivative represented
Prior art date
Application number
KR1019900004181A
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Korean (ko)
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KR920005745B1 (en
Inventor
김완주
이태석
김문환
하재두
남근수
Original Assignee
채영복
재단법인 한국화학연구소
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Priority to KR1019900004181A priority Critical patent/KR920005745B1/en
Publication of KR910016759A publication Critical patent/KR910016759A/en
Application granted granted Critical
Publication of KR920005745B1 publication Critical patent/KR920005745B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems

Abstract

내용 없음No content

Description

벤즈옥사진계 유도체와 그의 제조방법Benzoxazine derivatives and preparation method thereof

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (3)

다음 구조식(Ⅰ)로 표시되는 벤즈옥사진계 유도체와 약제학적으로 허용가능한 산 첨가염.A benzoxazine derivative represented by the following structural formula (I) and a pharmaceutically acceptable acid addition salt. 윗 식에서, R1과 R2는 각각 수소원자 또는 저급알킬기이고, n은 1 또는 2이다.Wherein R 1 and R 2 are each a hydrogen atom or a lower alkyl group, and n is 1 or 2; 다음 구조식(Ⅱ)로 표시되는 벤즈옥사진 카르복실산 유도체와 다음 구조식(Ⅲ)으로 표시되는 화합물 또는 그의 염을 상은 내지 200℃의 온도범위내에서 1내지 10시간 동안 반응시켜 제조됨을 특징으로 하는 다음 구조식(Ⅰ)로 표시되는 벤즈옥사진계 유도체의 제조방법.The benzoxazine carboxylic acid derivative represented by the following structural formula (II) and the compound represented by the following structural formula (III) or a salt thereof are prepared by reacting for 1 to 10 hours in the temperature range of 200 ° C. Method for producing a benzoxazine derivative represented by the following structural formula (I). 윗 식에서 X는 할로겐이고, R1과 R2는 각각 수소원자 또는 저급알킬기이며, n은 1또는 2이다.Wherein X is halogen, R 1 and R 2 are each a hydrogen atom or a lower alkyl group, and n is 1 or 2; 다음 구조식(Ⅰ)로 표시되는 화합물을 유효성분으로 하는 것을 특징으로 하는 항균제.An antimicrobial agent characterized by having the compound represented by the following structural formula (I) as an active ingredient. 윗 식에서, R1과 R2는 수소원자 또는 저급알킬기이고, n은 1 또는 2이다.Wherein R 1 and R 2 are hydrogen or lower alkyl and n is 1 or 2. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019900004181A 1990-03-28 1990-03-28 Benzoxazine derivatives and its preparation process KR920005745B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019900004181A KR920005745B1 (en) 1990-03-28 1990-03-28 Benzoxazine derivatives and its preparation process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019900004181A KR920005745B1 (en) 1990-03-28 1990-03-28 Benzoxazine derivatives and its preparation process

Publications (2)

Publication Number Publication Date
KR910016759A true KR910016759A (en) 1991-11-05
KR920005745B1 KR920005745B1 (en) 1992-07-18

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KR1019900004181A KR920005745B1 (en) 1990-03-28 1990-03-28 Benzoxazine derivatives and its preparation process

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Publication number Publication date
KR920005745B1 (en) 1992-07-18

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