KR910002944B1 - 테트라히드로나프탈레놀 유도체 및 그의 제조 방법 - Google Patents

테트라히드로나프탈레놀 유도체 및 그의 제조 방법 Download PDF

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Publication number
KR910002944B1
KR910002944B1 KR1019850003375A KR850003375A KR910002944B1 KR 910002944 B1 KR910002944 B1 KR 910002944B1 KR 1019850003375 A KR1019850003375 A KR 1019850003375A KR 850003375 A KR850003375 A KR 850003375A KR 910002944 B1 KR910002944 B1 KR 910002944B1
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KR
South Korea
Prior art keywords
alkyl
compound
hydrogen
alkoxy
tetrahydro
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Expired
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KR1019850003375A
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English (en)
Korean (ko)
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KR850008659A (ko
Inventor
에스. 애트월 카네일
Original Assignee
이이. 아르. 스퀴부 앤드 산즈 인코오포레이티드
죠오지 제이. 코에서
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Application filed by 이이. 아르. 스퀴부 앤드 산즈 인코오포레이티드, 죠오지 제이. 코에서 filed Critical 이이. 아르. 스퀴부 앤드 산즈 인코오포레이티드
Publication of KR850008659A publication Critical patent/KR850008659A/ko
Application granted granted Critical
Publication of KR910002944B1 publication Critical patent/KR910002944B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019850003375A 1984-05-17 1985-05-17 테트라히드로나프탈레놀 유도체 및 그의 제조 방법 Expired KR910002944B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61125884A 1984-05-17 1984-05-17
US611258 1984-05-17

Publications (2)

Publication Number Publication Date
KR850008659A KR850008659A (ko) 1985-12-21
KR910002944B1 true KR910002944B1 (ko) 1991-05-11

Family

ID=24448300

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850003375A Expired KR910002944B1 (ko) 1984-05-17 1985-05-17 테트라히드로나프탈레놀 유도체 및 그의 제조 방법

Country Status (13)

Country Link
EP (1) EP0163458A1 (enExample)
JP (1) JPS60260546A (enExample)
KR (1) KR910002944B1 (enExample)
AU (1) AU573828B2 (enExample)
DK (1) DK219885A (enExample)
ES (2) ES8701144A1 (enExample)
FI (1) FI851969A7 (enExample)
GR (1) GR851204B (enExample)
HU (1) HUT38298A (enExample)
IL (1) IL75224A (enExample)
NZ (1) NZ212112A (enExample)
PT (1) PT80481B (enExample)
ZA (1) ZA853759B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE56944T1 (de) * 1986-07-28 1990-10-15 Whitby Research Inc Substituierte 2-aminotetraline.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267373A (en) * 1972-07-03 1981-05-12 E. R. Squibb & Sons, Inc. 5,6,7,8-Tetrahydronaphthalene hypotensive agents
US3930022A (en) * 1972-07-03 1975-12-30 Squibb & Sons Inc Certain tetrahydronaphthalenes used in the treatment of cardiac arrhythmia
GB1442851A (en) * 1973-07-09 1976-07-14 Squibb & Sons Inc Substituted cyclic polymethylene phenols
AU8194275A (en) * 1974-06-17 1976-12-16 Takeda Chemical Industries Ltd Aminotetralin compounds
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
NZ213651A (en) * 1984-10-11 1989-07-27 Hoffmann La Roche Tetrahydronapthalene derivatives and medicaments

Also Published As

Publication number Publication date
KR850008659A (ko) 1985-12-21
ES552087A0 (es) 1987-05-01
FI851969A0 (fi) 1985-05-17
AU573828B2 (en) 1988-06-23
FI851969L (fi) 1985-11-18
NZ212112A (en) 1988-10-28
PT80481A (en) 1985-06-01
ES543242A0 (es) 1986-11-16
PT80481B (en) 1987-01-15
AU4254785A (en) 1985-11-21
HUT38298A (en) 1986-05-28
ES8705363A1 (es) 1987-05-01
IL75224A (en) 1988-11-15
GR851204B (enExample) 1985-11-25
JPS60260546A (ja) 1985-12-23
DK219885A (da) 1985-11-18
ZA853759B (en) 1986-01-29
FI851969A7 (fi) 1985-11-18
DK219885D0 (da) 1985-05-17
EP0163458A1 (en) 1985-12-04
ES8701144A1 (es) 1986-11-16
IL75224A0 (en) 1985-09-29

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Patent event date: 19850517

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