KR900018032A - 2,3-디클로로-5-아세틸피리딘의 제조방법 - Google Patents
2,3-디클로로-5-아세틸피리딘의 제조방법 Download PDFInfo
- Publication number
- KR900018032A KR900018032A KR1019890006062A KR890006062A KR900018032A KR 900018032 A KR900018032 A KR 900018032A KR 1019890006062 A KR1019890006062 A KR 1019890006062A KR 890006062 A KR890006062 A KR 890006062A KR 900018032 A KR900018032 A KR 900018032A
- Authority
- KR
- South Korea
- Prior art keywords
- formula
- compound
- alkyl
- halide
- acetylpyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (3)
- (a)일반식(Ⅱ)의 5,6-디클로로니코티노일 할라이드를 마그네슘 화합물 및 염기의 존재하에 일반식(Ⅲ)의 말론산 에스테르와 반응시킨 후, 생성물을 수성산의존재하에서 온화하게 탈카복실화시키거나, (b)일반식(Ⅳ)의 화합물을 물의 존재하에, 필요한 경우 유기 용매의 존재하 및, 필요한 경우 프로톤산의 존재하에 50 내지 180℃의 온도에서 탈카복실화시키거나, (c)일반식(Ⅱ)의 5,6-디클로로니코티노일 할라이드를 촉매의 존재하에 일반식(Ⅴ)의 메틸마그네슘 할라이드와 반응시키거나, (d)구조(Ⅵ)의 5,6-디클로로니코틴산을 메틸리륨과 반응시킴을 특징으로 하여, 구조(I)의 2,3-디클로로-5-아세틸피리딘을 제조하는 방법.상기식에서 Haℓ은 할로겐이고, R1은 C1-3-알킬이다.
- 일반식(Ⅳ)의 화합물.상기식에서 R1은C1-3-알킬이다
- 일반식(Ⅱ)의 화합물을 마그네슘염 및 염기의 존재하에 일반식(Ⅲ)의 말론산 에스테르와 반응시킴을 특징으로 하여, 제2항에 따른 일반식(Ⅳ)의 화합물을 제조하는 방법.상기식에서 Haℓ은 할로겐이고, R1은 C1-3-알킬이다.※ 참고사항 : 최초출원내용에 의하여 공개하는 것임.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP3815727.6 | 1988-05-07 | ||
DE3815727 | 1988-05-07 | ||
DE3838243A DE3838243A1 (de) | 1988-05-07 | 1988-11-11 | Verfahren zur herstellung von 2,3-dichlor-5-acetylpyridin |
DEP3838243.1 | 1988-11-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR900018032A true KR900018032A (ko) | 1990-12-20 |
Family
ID=25867909
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019890006062A KR900018032A (ko) | 1988-05-07 | 1989-05-06 | 2,3-디클로로-5-아세틸피리딘의 제조방법 |
Country Status (5)
Country | Link |
---|---|
US (1) | US5149822A (ko) |
EP (1) | EP0341478A3 (ko) |
JP (1) | JPH01319461A (ko) |
KR (1) | KR900018032A (ko) |
DE (1) | DE3838243A1 (ko) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE64614B1 (en) * | 1990-03-14 | 1995-08-23 | Lonza Ag | A method of preparing 2,3-dichloro-5-acetyl pyridine |
AU5896096A (en) * | 1995-05-26 | 1996-12-11 | Bayer Aktiengesellschaft | Pyridyl-thiazoles and their use to protect plants against in fections by micro-organisms |
US20100016603A1 (en) * | 2007-01-29 | 2010-01-21 | Fujifilm Finechemicals Co., Ltd. | Production process of 2,3'-bipyridyl-6'-one |
EP3666759A1 (en) | 2018-12-10 | 2020-06-17 | Bayer Aktiengesellschaft | Preparation of 6-halo-2-(haloalkyl)-3-acylpyridines and intermediates therefor |
EP3738959A1 (en) | 2019-05-16 | 2020-11-18 | Bayer AG | Preparation of 6-phenoxy-2-(haloalkyl)-3-acylpyridines and intermediates therefor |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1207954A (en) * | 1966-10-24 | 1970-10-07 | Lilly Industries Ltd | Novel adamantane derivatives, the preparation thereof and compositions containing the same |
US4358455A (en) * | 1980-12-23 | 1982-11-09 | Merck & Co., Inc. | Aralkylamindethanol heterocyclic compounds |
DE3615293A1 (de) * | 1986-05-06 | 1987-11-12 | Bayer Ag | Verwendung von heteroarylethylaminen zur leistungsfoerderung bei tieren, heteroarylethylamine und verfahren zu ihrer herstellung |
DE3723070A1 (de) * | 1987-07-11 | 1989-01-19 | Bayer Ag | Verfahren zur herstellung von substituierten pyridylalkylketonen |
JP2765921B2 (ja) * | 1989-03-09 | 1998-06-18 | 三洋電機株式会社 | 遠隔発停装置 |
-
1988
- 1988-11-11 DE DE3838243A patent/DE3838243A1/de not_active Withdrawn
-
1989
- 1989-04-12 US US07/336,969 patent/US5149822A/en not_active Expired - Fee Related
- 1989-04-24 EP EP19890107347 patent/EP0341478A3/de not_active Withdrawn
- 1989-05-02 JP JP1112320A patent/JPH01319461A/ja active Pending
- 1989-05-06 KR KR1019890006062A patent/KR900018032A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE3838243A1 (de) | 1989-11-16 |
EP0341478A2 (de) | 1989-11-15 |
EP0341478A3 (de) | 1992-01-08 |
JPH01319461A (ja) | 1989-12-25 |
US5149822A (en) | 1992-09-22 |
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Date | Code | Title | Description |
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WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |