KR900016214A - Triazolopyrazinone derivatives and preparation method thereof - Google Patents

Triazolopyrazinone derivatives and preparation method thereof Download PDF

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Publication number
KR900016214A
KR900016214A KR1019890005694A KR890005694A KR900016214A KR 900016214 A KR900016214 A KR 900016214A KR 1019890005694 A KR1019890005694 A KR 1019890005694A KR 890005694 A KR890005694 A KR 890005694A KR 900016214 A KR900016214 A KR 900016214A
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South Korea
Prior art keywords
general formula
formula
triazolopyrazinone
derivative
derivatives
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KR1019890005694A
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Korean (ko)
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KR910003154B1 (en
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이기정
박호군
김성곤
엄현숙
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이상수
한국과학기술원
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Priority to KR1019890005694A priority Critical patent/KR910003154B1/en
Priority to JP2108995A priority patent/JPH07621B2/en
Publication of KR900016214A publication Critical patent/KR900016214A/en
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Publication of KR910003154B1 publication Critical patent/KR910003154B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음.No content.

Description

트리아졸로피라지논 유도체 및 그의 제조방법Triazolopyrazinone derivatives and preparation method thereof

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (5)

다음 일반식(I)로 표시되는 신규한 트리아졸로피라지논 유도체.A novel triazolopyrazinone derivative represented by the following general formula (I). 일반식(I)에 있어서 R은 수소, 메틸, 에틸 또는 사이클로 프로필기를 표시한다.In general formula (I), R represents hydrogen, methyl, ethyl, or a cyclopropyl group. 다음 일반식(VIII)의 옥사릴티오세미카바지드를 암모니아수 또는 일급 아민과 반응시켜 신규한 다음 일반식(IX) 의 옥사모일티오세미카바지드를 제조하는 제1공정과, 일반식(IX)의 옥사모일티오세미카바지드를 염기성 수용액에서 반응시켜 다음 일반식(X)의 트리아졸린유도체를 제조하는 제2공정 및 일반식(X)의 트리아졸린유도체를 산성 수용액에서 반응시켜 다음 일반식(I) 의 트리아졸로피라지논 유도체를 제조하는 제3공정으로 이루어진 것을 특징으로 하는 다음 일반식(I)의 트리아졸로피라지논 유도체의 제조방법.The first step of reacting oxarylyl thiamicarbazide of formula (VIII) with aqueous ammonia or primary amine to produce new oxamoyl thiomicarbazide of formula (IX), and of formula (IX) The second step of preparing oxamoyl thiosemicarbazide in a basic aqueous solution to produce a triazoline derivative of the general formula (X) and the triazoline derivative of the general formula (X) in an acidic aqueous solution are carried out in the following general formula (I) A process for producing a triazolopyrazinone derivative of the following general formula (I), comprising the third step of preparing a triazolopyrazinone derivative. 일반식(I), 일반식(IX) 및 일반식(X)에 있어서, R은 수소, 메틸, 에틸 또는 사이클로프로필기를 표시한다.In general formula (I), general formula (IX), and general formula (X), R represents hydrogen, methyl, ethyl, or a cyclopropyl group. 제2항에 있어서, 제1공정의 일급아민이 메틸아민, 에틸아민, 사이클로프로필아민 중에서 선택됨을 특징으로 하는 일반식(I)의 트리아졸로피라지논 유도체의 제조방법.3. The process for producing triazolopyrazinone derivatives of formula (I) according to claim 2, wherein the primary amine of the first step is selected from methylamine, ethylamine and cyclopropylamine. 제2항에 있어서, 제2공정의 염기성 수용액이 탄산수소나트륨, 탄산수소칼륨, 탄산나트륨, 탄산칼륨, 수산화나트륨, 수산화칼륨 중에서 선택됨을 특징으로 하는 일반식(I)의 트리아졸로피라지논 유도체의 제조방법.3. The preparation of triazolopyrazinone derivatives of the general formula (I) according to claim 2, wherein the basic aqueous solution of the second step is selected from sodium hydrogen carbonate, potassium hydrogen carbonate, sodium carbonate, potassium carbonate, sodium hydroxide and potassium hydroxide. Way. 제2항에 있어서, 제3공정의 산성수용액이 염산, 황산, 초산중에서 선택됨을 특징으로 하는 일반식(I)의 트리아졸로 피라지논 유도체의 제조방법.3. The process for producing triazolo pyrazinone derivatives of formula (I) according to claim 2, wherein the acidic aqueous solution of the third step is selected from hydrochloric acid, sulfuric acid and acetic acid. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019890005694A 1989-04-29 1989-04-29 Triazolopirazinone derivatives and its preparation process KR910003154B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1019890005694A KR910003154B1 (en) 1989-04-29 1989-04-29 Triazolopirazinone derivatives and its preparation process
JP2108995A JPH07621B2 (en) 1989-04-29 1990-04-26 Triazolopyrazinone derivative and method for producing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019890005694A KR910003154B1 (en) 1989-04-29 1989-04-29 Triazolopirazinone derivatives and its preparation process

Publications (2)

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KR900016214A true KR900016214A (en) 1990-11-12
KR910003154B1 KR910003154B1 (en) 1991-05-20

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KR1019890005694A KR910003154B1 (en) 1989-04-29 1989-04-29 Triazolopirazinone derivatives and its preparation process

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JP (1) JPH07621B2 (en)
KR (1) KR910003154B1 (en)

Also Published As

Publication number Publication date
KR910003154B1 (en) 1991-05-20
JPH07621B2 (en) 1995-01-11
JPH03148281A (en) 1991-06-25

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