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Application filed by 이승철, 주식회사 대웅제약filedCritical이승철
Priority to KR1019910017164ApriorityCriticalpatent/KR930007923A/en
Publication of KR930007923ApublicationCriticalpatent/KR930007923A/en
본 발명은 다음과 같은 구조식(Ⅰ)으로 표시되는 클로로신나진 염산염의 새롭고 진보된 제조방법에 관한 것이다. 이 물질은 강력한 항히스타민제로서 유용하며 구체적인 제조방법은 아래와 같다.The present invention relates to a new and advanced method for preparing chlorocinnaline hydrochloride represented by the following structural formula (I). This substance is useful as a powerful antihistamine and the specific preparation method is as follows.
Description
클로로신나진 염산염의 제조방법Method for preparing chlorocinnaline hydrochloride
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.
Claims (2)
구조식(Ⅳ)의 화합물과 구조식(Ⅴ)의 화합물을 반응시키고 염산을 사용하여 구조식(Ⅰ)의 클로르신나진 염산염을 제조하는 방법.A method of reacting a compound of formula (IV) with a compound of formula (V) and preparing hydrochlorinazine hydrochloride of formula (I) using hydrochloric acid.제 1 항에 있어서, 상기 치환반응에 사용되는 염기로서 트리에틸아민과 탄산칼륨의 혼합사용을 특징으로 하는 클로로신나진 염산염의 제조방법.The method for producing chlorocinnaginate hydrochloride according to claim 1, wherein a mixture of triethylamine and potassium carbonate is used as a base used in the substitution reaction.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019910017164A1991-10-011991-10-01
Method for preparing chlorcinazine hydrochloride
KR930007923A
(en)