KR890006212A - 소르보하이드록삼산을 포함하는 광보호조성물 - Google Patents

소르보하이드록삼산을 포함하는 광보호조성물 Download PDF

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KR890006212A
KR890006212A KR1019880013805A KR880013805A KR890006212A KR 890006212 A KR890006212 A KR 890006212A KR 1019880013805 A KR1019880013805 A KR 1019880013805A KR 880013805 A KR880013805 A KR 880013805A KR 890006212 A KR890006212 A KR 890006212A
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acid
composition
ethylhexyl
acid ester
ester
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KR1019880013805A
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채터지 랜지트
존 키르크너 스테펜
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원본 미기재
더 프록터 앤드 갬블 캄파니
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Publication of KR890006212A publication Critical patent/KR890006212A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8135—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an acyloxy radical of a saturated carboxylic acid, of carbonic acid or of a haloformic acid; Compositions of derivatives of such polymers, e.g. vinyl esters (polyvinylacetate)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/05—Stick

Abstract

내용 없음

Description

소르보하이드록삼산을 함유하는 광보호조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 안전한 광 보호적 유효량, 바람직하게는 1% 내지 20%, 더욱 바람직하게는 2% 내지 5%의 소르보하이드록삼산 및 약제학적으로 허용되는 이의 염으로부터 선택되는 약제, 및 안전한 유효량의국소적 담체를 함유함을 특징으로하는, 바람직하게는 로션, 크림, 겔, 에어로졸 스프레이, 향장적 파운데이션 또는 립스틱 형태로 국소 적용하기에 유용한 조성물.
  2. 제1항에 있어서, 담체가 바람직하게는 탄화수소 오일 및 왁스, 실리콘 오일, 트리글리세라이드 에스테르, 아세토글리세라이드 에스테르, 에톡실화된 글리세라이드, 지방산의 알킬 에스테르, 지방산의 알케닐 에스테르, 지방산, 지방 알코올, 지방 알코올 에테르, 에톡실화된 지방 알코올의 지방산 에스테르, 에테르- 에스테르,라놀린 및 이외 유도체, 다가 알코올, 폴리에케르 유도체, 다가 알코올 에스테르, 왁스 에스테르, 밀납 유도체, 식물성 왁스, 인지질, 스테롤, 아미드, 하기 일반식의 프로폭실화된 글리세롤 유도체 및 이의 유도체로부터 선택된 연화제를 함유함을 특징으로 하는 조성물.
    상기식에서, n은 1 또는 2이다.
  3. 제1항에 있어서, 담체가(a) 필수적으로 적어도 하나의 액체 오가노폴리실옥산으로 이루어지는 실리콘 유체 연속 상의 유체 조성물 15중량% 내지 90중량%; (b) 수성상 중에 분산된 향장학적으로 허용되는 유성 액체 비미립자성 상의 수중유형 유제를 함유하는 수성 불연속상의 유제 조성물 30중량% 내지 80중량%; 및 (c)(a)중에 (b)를 분산시키기 위한 분산 유효량의 디메티콘 코풀리올의 유체 조성물 0.5중량% 내지 5중량%를 함유하는 실리콘 중 수중 유형의 유체 유제조성물을 함유함을 특징으로 하는 조성물.
  4. 1항에 있어서, 담체가 하기 일반식의 에틸렌 아크릴산 공중합체 약0.25% 내지 약 3%를 함유함을 특징으로 하는 조성물.
    상기식에서, X:Y의 비는 1:9 내지 1:24이고, 공중 합체의 분자량은 3500내지4500이다.
  5. 담체가 향장학적으로 허용되는 계면활성제를 바람직하게는 5% 내지 80%함유함을 특징으로하여 바람직하게는 봉 비누(bar soap), 액체 비누, 페이스트 또는 무수형태로 피부를 세정하는데 유용한 제1항의 조성물.
  6. 제1항 내지 제4항중 어느 한 항에 있어서, 추가로 안전한 유효량의 침투 촉진제를 함유함을 특징으로 하는 조성물.
  7. 제1항 내지 제4항중 어느 한 항에 있어서, 추가로 바람직하게는 2- 에틸헥실 P- 메톡시신나메이트, 부틸메톡시디벤조일메탄, 2-하이드록시 -4-메톡시벤조페논, 옥틸-디메틸 P-아미노벤조산, 2,4-디하이드록시벤조펜논의 4-N,N-(2-에틸헥실)메틸-아미노벤조산 에스테르, 4-하이드록시벤조일메탄의 N,N-디-(2-에틸헥실)-4-아미노벤조산에스테르, 4-하이드록시-디-벤조일메탄의 4-N,N-(2-에틸헥실)메틸아미노벤조산 에스테르, 2-하이드록시-4-(2-하이드록시에톡시) 벤조펜논의 4-N-N-디 (2-에틸헥실)- 메틸 아미노벤조산 에스테르, 4-(2-하이드록시에톡시)디벤조일 메탄의 4-N,N-(-에탈헥실)메틸아미노벤조산 에스테르, 2-하이드록시-4-(2-하이드록시에톡시)벤조페논의 N-N-디-(2-에틸-헥실)-4-아미노벤조산 에스테. 4-(2-하이드록시에톡시)디벤조일메탄의 N,N-디-(2에닐헥실)-4-아미노벤조산 에스테르, 및 이의 혼합물로부터 선택된 일광 차단제를 안전한 광 보호 유효량, 바람직하게는 1% 내지 10% 함유함을 특징으로 하는 조성물.
  8. 제1항 내지 7항중 어느 한 항에 있어서, 추가로 아스코르브산 및 이의 염, 토코페롤, 토코페롤 에스테르, 부틸화된 하이드록시벤조산 및 이의 염, 6-하이드록시-2,5,7,8-4급 메틸코르만 -2-카복실산, 갈산 및 이의 알킬 에스테르, 우르산 미 이의 염, 염 및 에스테르, 소르브산 및 이의 염, 지방산의 아스코르빌 에스테르, 아민, 설프하이드릴 화합물, 디하이드록시 푸마르산 및 이의 염 및 이의 혼합물로부터 선된 라디칼 스케빈징 화합물, 바람직하게는 토코페롤 소르베이트르를 안정한 광보호 유효량, 바람직하게는 1% 내지 20%, 더욱 바람직하게는 2% 내지 5% 함유함을 특징으로 하는 조성물.
  9. 피부에 대한 자외선 노출의 유해한 영향을 억제하기 위한 국소적 조성물을 피부에 적용하여 바람직하게는 0.01mg/㎠ 내지 1.0mg/㎠ , 더욱 바람직하게는 0.05mg/㎠ 내지 0.5mg/㎠ 의 소르보하이드록삼산 또는 약제학적으로 허용되는 이의 염을 자외선에 피부를 노출시키기 전 4시간 이내에 피부에 적용시키도록 상기 국소적 조성물을 제조하기 위한 소르보하이드록삼산, 또는 약제학적으로 허용되는 이의 염의 용도.
  10. 제9항에 있어서, 조성물이 바람직하게는 2-에틸헥실 P-메톡시신나메이트, 메틸 메톡시벤조일메탄, 2-하이드록시-4-메톡시벤조페논, 옥틸디메틸 P-아미노벤조산, 디하이드록시벤조페논의 4-N,N-(2-에틸헥실)메틸-아미노벤조산 에스테르, 하이드록시벤조일데탄의 N,N-디-(에틸헥실)-4-아미노벤조산 에스테르, 4-하이드록시벤조일메탄의 4-N,N-(2-에틸헥실)메틸아미노 벤조산 에스테르, 2-하이드록시-4-(2-하이드록시에톡시)벤조페논의 4-N,N-(2-에틸헥실)메틸아미노벤조산 에스테르, 4-(2-하이드록시에톡시)디벤조일메탄의 4-N.N-)2-에틸헥실)메틸아미노벤조산 에스테르, 2-하이드록시-4-(2-하이드록시에톡시) -벤조페논의 N-N-디-(2-에틸-헥실)-4-아미노벤조산 에스테르, 4-(2-하이드록시에톡시)디벤조일 메탄의 N,N-디-(2-에틱헥실)-4-아미노벤조산 에스테르, 및 이의 혼합물로부터 선택된 일광 차단제를, 바람직하게는 0.01mg/cm/㎠내지 1.0mg/㎠ , 더욱 바람직하게는 0.05mg/㎠ 내지 0.5mg/㎠ 로 피부에 적용시킬 정도의 안정한 광 보호적 유효량으로 함유함을 특징으로 하는 용도.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880013805A 1987-10-22 1988-10-22 소르보하이드록삼산을 포함하는 광보호조성물 KR890006212A (ko)

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Application Number Priority Date Filing Date Title
US112,577 1987-10-22
US07/112,577 US4869897A (en) 1987-10-22 1987-10-22 Photoprotection compositions comprising sorbohydroxamic acid

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KR890006212A true KR890006212A (ko) 1989-06-12

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US (1) US4869897A (ko)
EP (1) EP0313302B1 (ko)
JP (1) JPH01265016A (ko)
KR (1) KR890006212A (ko)
AT (1) ATE70436T1 (ko)
AU (2) AU606834B2 (ko)
CA (1) CA1334007C (ko)
DE (1) DE3867027D1 (ko)
NZ (1) NZ226664A (ko)

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AU606834B2 (en) 1991-02-14
CA1334007C (en) 1995-01-17
DE3867027D1 (de) 1992-01-30
NZ226664A (en) 1991-03-26
AU618894B2 (en) 1992-01-09
EP0313302B1 (en) 1991-12-18
US4869897A (en) 1989-09-26
AU2408688A (en) 1989-04-27
AU5457390A (en) 1990-08-30
JPH01265016A (ja) 1989-10-23
EP0313302A3 (en) 1989-08-09
ATE70436T1 (de) 1992-01-15
EP0313302A2 (en) 1989-04-26

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