KR890003395A - Diabetes treatment - Google Patents

Diabetes treatment Download PDF

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Publication number
KR890003395A
KR890003395A KR1019880007132A KR880007132A KR890003395A KR 890003395 A KR890003395 A KR 890003395A KR 1019880007132 A KR1019880007132 A KR 1019880007132A KR 880007132 A KR880007132 A KR 880007132A KR 890003395 A KR890003395 A KR 890003395A
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South Korea
Prior art keywords
acid
inorganic
organic acid
vacuum
mmhg
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KR1019880007132A
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Korean (ko)
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KR930002010B1 (en
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요이찌 이시이
히사시 미하라
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요이찌 이시이
가부시끼가이샤 에이메이
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

내용 없음No content

Description

당뇨병 치료제Diabetes treatment

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (7)

지렁이 건조분말을 유효성분으로 하는 당뇨병 치료제.Diabetes treatment agent with earthworm dry powder as an active ingredient. 생 지렁이를 유기산, 무기산, 유기산 나트륨염, 무기산 나트륨염, 유기산 칼륨염 및 무기산 칼륨염으로서 된 군에서 선택된 적어도 1종류의 화합물을 0.3%(중량)%이하 함유하는 수용액 또는 진수중에 방치하여 생 지렁이의 소화관내의 분토를 토하게 한 다음, 생지렁이의 체표면에 부착한 오물을 물로 세척 제거하고, 다음에 습식 분쇄를 행하고, 이 현탁액을 -10∼60℃로 동결한 다음 -60∼80℃의 범위내에서 온도를 단계적으로 올리면서 10mmHg 이하의 진공도로서 10∼100시간 동결·진공건조를 행하고, 이중, 최종 공정의 진공건조를 70∼80℃로 0.01∼0.5mmHg의 진공하에서 5∼10시간 건조하는 것을 특징으로 하는 지렁이 건조분말을 유효성분으로 하는 당뇨병 치료제.Raw earthworms are left in an aqueous solution or in water containing 0.3% (weight)% or less of at least one compound selected from the group consisting of organic acid, inorganic acid, organic acid sodium salt, inorganic acid sodium salt, organic acid potassium salt and inorganic acid potassium salt. Vomiting vomiting in the digestive tract of the digestive tract, followed by washing and removing dirt adhered to the body surface of the live earthworm, followed by wet grinding, and freezing the suspension to -10 to 60 ° C and then to -60 to 80 ° C. Freezing and vacuum drying are carried out for 10 to 100 hours at a vacuum degree of 10 mmHg or less while gradually raising the temperature within the range, and among these, the vacuum drying of the final process is dried at 70 to 80 ° C. under a vacuum of 0.01 to 0.5 mmHg for 5 to 10 hours. Diabetes treatment agent comprising earthworm dry powder, characterized in that the active ingredient. 제2항에 있어서, 유기산이 초산, 구연산, 호박산, 사과산, 주석산 또는 젖산인 항고지혈증제.The antihyperlipidemic agent according to claim 2, wherein the organic acid is acetic acid, citric acid, succinic acid, malic acid, tartaric acid or lactic acid. 제2항에 있어서, 무기산이 인산, 황산 또는 염산인 당뇨병 치료제.The agent for treating diabetes of claim 2, wherein the inorganic acid is phosphoric acid, sulfuric acid or hydrochloric acid. 생 지렁이의 체표면에 부착한 오물을 물로 세척 제거한 다음, 생 지렁이를 유기산, 무기산, 유기산 나트륨염, 무기산 나트륨염, 유기산 칼륨염 및 무기산 칼륨염으로 된 군에서 선택된 적어도 1종류의 화합물을 0.3(중량)%이하 함유하는 수용액중 또는 진수중에 방치하여 생 지렁이의 소화관내의 분토를 토하게 한 다음 다음에 습식 분쇄를 행하고, 이 현탁액을 -10∼60℃로 동결한 다음 -60∼80℃의 범위내에서 온도를 단계적으로 올리면서 10mmHg 이하의 진공도로서 10∼100시간 동결·진공건조를 행하고, 이중, 최종 공정의 진공건조를 70∼80℃로 0.01∼0.5mmHg의 진공하에서 5∼10시간 건조하는 것을 특징으로 하는 지렁이 건조분말을 유효성분으로 하는 당뇨병 치료제.The soils attached to the body surface of the live earthworms are washed with water, and then, at least one compound selected from the group consisting of organic acid, inorganic acid, organic acid sodium salt, inorganic acid sodium salt, organic acid potassium salt and inorganic acid potassium salt is 0.3 ( The mixture is left in an aqueous solution containing up to% by weight or in launching to induce vomiting in the digestive tract of the live earthworm, followed by wet grinding. The suspension is frozen at -10 to 60 ° C and then in the range of -60 to 80 ° C. Freezing and vacuum drying are carried out for 10 to 100 hours at a vacuum degree of 10 mmHg or less while gradually raising the temperature in the interior, and among these, the vacuum drying of the final process is dried at 70 to 80 ° C. under a vacuum of 0.01 to 0.5 mmHg for 5 to 10 hours. Diabetes treatment agent comprising an earthworm dry powder, characterized in that the active ingredient. 제5항에 있어서, 유기산이 초산, 구연산, 호박산, 사과산, 주석산 또는 젖산인 당뇨병 치료제.The antidiabetic agent according to claim 5, wherein the organic acid is acetic acid, citric acid, succinic acid, malic acid, tartaric acid or lactic acid. 제5항에 있어서, 무기산이 인산, 황산 또는 염산인 당뇨병 치료제.The antidiabetic agent according to claim 5, wherein the inorganic acid is phosphoric acid, sulfuric acid or hydrochloric acid. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019880007132A 1987-08-18 1988-06-14 Antidiabetics KR930002010B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP62204905A JPH0780778B2 (en) 1987-08-18 1987-08-18 Antidiabetic agent
JP62-204905 1987-08-18
JP87-204905 1987-08-18

Publications (2)

Publication Number Publication Date
KR890003395A true KR890003395A (en) 1989-04-14
KR930002010B1 KR930002010B1 (en) 1993-03-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880007132A KR930002010B1 (en) 1987-08-18 1988-06-14 Antidiabetics

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JP (1) JPH0780778B2 (en)
KR (1) KR930002010B1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100363197B1 (en) * 2000-07-11 2002-12-05 (주)이오바이오텍 the extracting method of earthworm's body fluids using water contained activated oxygen
KR100557892B1 (en) * 2002-03-29 2006-03-10 보은군 loess include earthworm powder and a method of processing thereof

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4699974B2 (en) * 2006-09-29 2011-06-15 Well Stone 有限会社 Method for producing earthworm dry powder
US8137701B2 (en) 2008-03-21 2012-03-20 Well Stone Co. Method of producing a dry earthworm powder
ATE475425T1 (en) 2008-03-26 2010-08-15 Well Stone Co METHOD FOR PRODUCING DRY EARTHWORM POWDER
JP4886017B2 (en) 2009-10-13 2012-02-29 Well Stone 有限会社 Method for producing earthworm dry powder
JP4808822B1 (en) 2011-04-11 2011-11-02 Well Stone 有限会社 Method for producing earthworm dry powder
JP6047609B2 (en) * 2014-03-29 2016-12-21 国立大学法人 新潟大学 Composition for inhibiting fatty liver and renal hypertrophy due to diabetes and method for producing the same
JP5901092B1 (en) * 2015-08-26 2016-04-06 ワキ製薬株式会社 Method for producing human dipeptidyl peptidase IV inhibitor
KR101884939B1 (en) * 2016-10-24 2018-08-03 안동대학교 산학협력단 Composition containing Lumbricus rubellus extract reducing lipid accumulation as effective component
AU2018240774B2 (en) 2017-03-21 2023-01-12 Well Stone Co. Method for producing therapeutic agent for skin lesions, and therapeutic agent for skin lesions
EP3603652B1 (en) 2017-03-21 2023-12-13 Well Stone Co. Production method of nasal drop composition and its use
JP6249581B1 (en) * 2017-06-12 2017-12-20 ワキ製薬株式会社 Method for producing carbohydrase inhibitor

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100363197B1 (en) * 2000-07-11 2002-12-05 (주)이오바이오텍 the extracting method of earthworm's body fluids using water contained activated oxygen
KR100557892B1 (en) * 2002-03-29 2006-03-10 보은군 loess include earthworm powder and a method of processing thereof

Also Published As

Publication number Publication date
JPH0780778B2 (en) 1995-08-30
KR930002010B1 (en) 1993-03-20
JPS6447718A (en) 1989-02-22

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