KR880009015A - 알리머켑토아세틸시드논이민, 이의 제조방법 및 이의 용도 - Google Patents
알리머켑토아세틸시드논이민, 이의 제조방법 및 이의 용도 Download PDFInfo
- Publication number
- KR880009015A KR880009015A KR1019880000504A KR880000504A KR880009015A KR 880009015 A KR880009015 A KR 880009015A KR 1019880000504 A KR1019880000504 A KR 1019880000504A KR 880000504 A KR880000504 A KR 880000504A KR 880009015 A KR880009015 A KR 880009015A
- Authority
- KR
- South Korea
- Prior art keywords
- formula
- alkyl
- allyl
- pharmaceutically acceptable
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 238000002360 preparation method Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 claims abstract 6
- 150000003839 salts Chemical class 0.000 claims abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 5
- 239000002253 acid Substances 0.000 claims abstract 4
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 claims abstract 3
- 150000001875 compounds Chemical class 0.000 claims 6
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims 3
- 206010002383 Angina Pectoris Diseases 0.000 claims 2
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 150000001242 acetic acid derivatives Chemical class 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 125000001664 diethylamino group Chemical group [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 claims 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- -1 methylethyl Chemical group 0.000 claims 1
- 229910052698 phosphorus Inorganic materials 0.000 claims 1
- 239000011574 phosphorus Substances 0.000 claims 1
- LFGREXWGYUGZLY-UHFFFAOYSA-N phosphoryl Chemical group [P]=O LFGREXWGYUGZLY-UHFFFAOYSA-N 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP3702083.8 | 1987-01-24 | ||
| DE19873702083 DE3702083A1 (de) | 1987-01-24 | 1987-01-24 | Allylmercaptoacetyl-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR880009015A true KR880009015A (ko) | 1988-09-13 |
Family
ID=6319474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019880000504A Ceased KR880009015A (ko) | 1987-01-24 | 1988-01-23 | 알리머켑토아세틸시드논이민, 이의 제조방법 및 이의 용도 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4888333A (enExample) |
| EP (1) | EP0276710B1 (enExample) |
| JP (1) | JPS63201177A (enExample) |
| KR (1) | KR880009015A (enExample) |
| AT (1) | ATE70837T1 (enExample) |
| CA (1) | CA1309408C (enExample) |
| DE (2) | DE3702083A1 (enExample) |
| DK (1) | DK640687A (enExample) |
| ES (1) | ES2038700T3 (enExample) |
| GR (1) | GR3003738T3 (enExample) |
| HU (1) | HU203331B (enExample) |
| PH (1) | PH24709A (enExample) |
| ZA (1) | ZA88446B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3702083A1 (de) * | 1987-01-24 | 1988-08-04 | Cassella Ag | Allylmercaptoacetyl-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| US5221680A (en) * | 1988-01-14 | 1993-06-22 | Cassella Aktiengesellschaft | Substituted 3-aminosydnonimines |
| DE3800830A1 (de) * | 1988-01-14 | 1989-07-27 | Cassella Ag | Substituierte 3-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| DE4015236A1 (de) * | 1990-05-13 | 1991-11-14 | Cassella Ag | Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| DE3820210A1 (de) * | 1988-06-14 | 1989-12-21 | Cassella Ag | Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| DE3921460A1 (de) * | 1989-06-30 | 1991-01-03 | Cassella Ag | Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| DE4028679A1 (de) * | 1990-09-10 | 1992-03-19 | Cassella Ag | Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| DE4031373A1 (de) * | 1990-10-04 | 1992-04-09 | Cassella Ag | 3-piperazino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| WO1993018767A1 (de) * | 1992-03-24 | 1993-09-30 | Cassella Aktiengesellschaft | Verwendung von sydnoniminen zur behandlung erektiler dysfunktionen |
| WO1998047896A1 (en) * | 1997-04-22 | 1998-10-29 | Chugai Seiyaku Kabushiki Kaisha | Sydononimine derivatives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2930736A1 (de) * | 1979-07-28 | 1981-02-12 | Cassella Ag | Pharmakologisch wirksame, substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| DE3107933A1 (de) * | 1981-03-02 | 1982-09-16 | Cassella Ag, 6000 Frankfurt | Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| JPS5859977A (ja) * | 1981-10-06 | 1983-04-09 | Banyu Pharmaceut Co Ltd | 新規なｎ−アシルシドノンイミン誘導体およびその製法 |
| DE3526068A1 (de) * | 1985-07-20 | 1987-01-22 | Cassella Ag | Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische praeparate |
| DE3702083A1 (de) * | 1987-01-24 | 1988-08-04 | Cassella Ag | Allylmercaptoacetyl-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
-
1987
- 1987-01-24 DE DE19873702083 patent/DE3702083A1/de not_active Withdrawn
- 1987-12-07 DK DK640687A patent/DK640687A/da not_active Application Discontinuation
-
1988
- 1988-01-16 EP EP88100574A patent/EP0276710B1/de not_active Expired - Lifetime
- 1988-01-16 ES ES198888100574T patent/ES2038700T3/es not_active Expired - Lifetime
- 1988-01-16 DE DE8888100574T patent/DE3867073D1/de not_active Expired - Fee Related
- 1988-01-16 AT AT88100574T patent/ATE70837T1/de not_active IP Right Cessation
- 1988-01-22 CA CA000557105A patent/CA1309408C/en not_active Expired - Fee Related
- 1988-01-22 JP JP63011031A patent/JPS63201177A/ja active Pending
- 1988-01-22 PH PH36391A patent/PH24709A/en unknown
- 1988-01-22 HU HU88254A patent/HU203331B/hu not_active IP Right Cessation
- 1988-01-22 ZA ZA880446A patent/ZA88446B/xx unknown
- 1988-01-23 KR KR1019880000504A patent/KR880009015A/ko not_active Ceased
- 1988-08-10 US US07/230,846 patent/US4888333A/en not_active Expired - Fee Related
-
1992
- 1992-02-06 GR GR920400078T patent/GR3003738T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3702083A1 (de) | 1988-08-04 |
| HU203331B (en) | 1991-07-29 |
| GR3003738T3 (enExample) | 1993-03-16 |
| ES2038700T3 (es) | 1993-08-01 |
| EP0276710A1 (de) | 1988-08-03 |
| CA1309408C (en) | 1992-10-27 |
| ZA88446B (en) | 1988-07-22 |
| US4888333A (en) | 1989-12-19 |
| DK640687A (da) | 1988-06-25 |
| PH24709A (en) | 1990-10-01 |
| EP0276710B1 (de) | 1991-12-27 |
| HUT50142A (en) | 1989-12-28 |
| JPS63201177A (ja) | 1988-08-19 |
| DK640687D0 (da) | 1987-12-07 |
| DE3867073D1 (de) | 1992-02-06 |
| ATE70837T1 (de) | 1992-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19880123 |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19921224 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19880123 Comment text: Patent Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19951023 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 19960215 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 19951023 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |