KR880006184A - 2-클로로-4-((시아노메틸)티오)페닐 n-메틸 카바메이트 - Google Patents

2-클로로-4-((시아노메틸)티오)페닐 n-메틸 카바메이트 Download PDF

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Publication number
KR880006184A
KR880006184A KR870012775A KR870012775A KR880006184A KR 880006184 A KR880006184 A KR 880006184A KR 870012775 A KR870012775 A KR 870012775A KR 870012775 A KR870012775 A KR 870012775A KR 880006184 A KR880006184 A KR 880006184A
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KR
South Korea
Prior art keywords
cyanomethyl
thio
chloro
phenyl
methyl carbamate
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KR870012775A
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English (en)
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KR950008206B1 (ko
Inventor
레이프슈나이더 왈터
Original Assignee
게리 디. 스트리트
메렐 다우 파마슈티칼스 인코포레이티드
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Application filed by 게리 디. 스트리트, 메렐 다우 파마슈티칼스 인코포레이티드 filed Critical 게리 디. 스트리트
Publication of KR880006184A publication Critical patent/KR880006184A/ko
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Publication of KR950008206B1 publication Critical patent/KR950008206B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

2-클로로-4-((시아노메틸)티오)페닐 N-메틸 카바메이트
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (7)

  1. 2-클로로-4-((시아노메틸)티오)페닐 N-메틸 카바메이트.
  2. 암에 걸린 환자에게 치료적 유효량의 2-클로로-4-((시아노메틸)티오)페닐 N-메틸 카바메이트를 투여함을 특징으로 하여 암 환자를 치료하는 방법.
  3. 제2항에 있어서, 암이 유방암인 방법.
  4. 제2항에 있어서, 암이 폐암인 방법.
  5. 임파구성 백혈병에 걸린 환자에게 치료적 유효량의 2-클로로-4-((시아노메틸)티오)페닐 N-메틸 카바메이트를 투여함을 특징으로 하여 임파구성 백형병 환자를 치료하는 방법.
  6. 치료적 유효량의 2-클로로-4-((시아노메틸)티오)페닐 N-메틸 카바메이트오 하나 또는 그 이상의 약제학적으로 허용되는 담체 또는 부형제로 이루어짐을 특징으로 하는 약제학적 조성물.
  7. 2-클로로-4-((시아노메틸)티오)페놀을 메틸 이소시아네이트와 반응시킴을 특징으로 하여 2-클로로-4-((시아노메틸)티오)페닐 N-메틸 카바메이트를 제조한는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870012775A 1986-11-14 1987-11-13 2-클로로-4-((시아노메틸)티오)페닐 n-메틸 카바메이트 및 이의 제조방법, 및 이를 함유하는 약제학적 조성물 KR950008206B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/930,838 US4804682A (en) 1986-11-14 1986-11-14 2-chloro-4-((cyanomethyl)thio)phenyl N-methyl carbamate for treating carcinomas
US930838 1986-11-14

Publications (2)

Publication Number Publication Date
KR880006184A true KR880006184A (ko) 1988-07-22
KR950008206B1 KR950008206B1 (ko) 1995-07-26

Family

ID=25459854

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870012775A KR950008206B1 (ko) 1986-11-14 1987-11-13 2-클로로-4-((시아노메틸)티오)페닐 n-메틸 카바메이트 및 이의 제조방법, 및 이를 함유하는 약제학적 조성물

Country Status (10)

Country Link
US (1) US4804682A (ko)
EP (1) EP0267582B1 (ko)
JP (1) JPH07113010B2 (ko)
KR (1) KR950008206B1 (ko)
AT (1) ATE73133T1 (ko)
CA (1) CA1321601C (ko)
DE (1) DE3777083D1 (ko)
DK (1) DK165243C (ko)
ES (1) ES2033772T3 (ko)
GR (1) GR3003984T3 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0767394B2 (ja) * 1991-03-20 1995-07-26 三洋化成工業株式会社 化学発光増強剤、化学発光利用検出・定量法及びキット

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE665273A (ko) * 1964-06-12 1965-10-01

Also Published As

Publication number Publication date
DK165243C (da) 1993-03-22
KR950008206B1 (ko) 1995-07-26
DK597287D0 (da) 1987-11-13
JPH07113010B2 (ja) 1995-12-06
DK165243B (da) 1992-10-26
GR3003984T3 (ko) 1993-03-16
EP0267582A2 (en) 1988-05-18
CA1321601C (en) 1993-08-24
ATE73133T1 (de) 1992-03-15
EP0267582A3 (en) 1989-02-08
EP0267582B1 (en) 1992-03-04
DK597287A (da) 1988-05-15
ES2033772T3 (es) 1993-04-01
JPS63154657A (ja) 1988-06-27
US4804682A (en) 1989-02-14
DE3777083D1 (de) 1992-04-09

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