KR870007143A - 4,5-diphenyl-2-oxazole manufacturing method of water-soluble derivative of propionic acid - Google Patents

4,5-diphenyl-2-oxazole manufacturing method of water-soluble derivative of propionic acid Download PDF

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Publication number
KR870007143A
KR870007143A KR860011424A KR860011424A KR870007143A KR 870007143 A KR870007143 A KR 870007143A KR 860011424 A KR860011424 A KR 860011424A KR 860011424 A KR860011424 A KR 860011424A KR 870007143 A KR870007143 A KR 870007143A
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KR
South Korea
Prior art keywords
oxazole
diphenyl
manufacturing
water
soluble derivative
Prior art date
Application number
KR860011424A
Other languages
Korean (ko)
Inventor
알베르토 베로네시 파올로
Original Assignee
마리아쥴리 아나마르티네즈로실라
테라피콘에스. 알. 엘
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 마리아쥴리 아나마르티네즈로실라, 테라피콘에스. 알. 엘 filed Critical 마리아쥴리 아나마르티네즈로실라
Publication of KR870007143A publication Critical patent/KR870007143A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

내용 없음No content

Description

4,5-디페닐-2-옥사졸 푸로피온산의 수용성 유도체의 제조방법Method for producing a water-soluble derivative of 4,5-diphenyl-2-oxazole furopionic acid

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (1)

다음과 같은 구조식(Ⅶ)의 화합물의 용액이나 현탄액을 중탄산나트륨(Ⅷ), 라이신(IX), 알기닌(Ⅹ), 글루카민(XI) 또는 메글루민(XⅡ)의 수용액과 반응시킴을 특징으로 하는 일반구조식(Ⅰ)의 4,5-디페닐-2-옥사졸 푸로피온산의 수용성 유도체의 제조방법.A solution or suspension of a compound of the formula The manufacturing method of the water-soluble derivative of 4, 5- diphenyl- 2-oxazole furopionic acid of general structural formula (I) which is used. 여기서 R＋은 음이온성나트륨원자(Na＋)(Ⅱ) 또는 라이신(Ⅲ), 알기닌(Ⅳ), 글루카민(Ⅴ)이나 메글루민(Ⅵ)을 나타내며 (Ⅲ)(Ⅳ)(Ⅴ) 및 (Ⅵ)의 아민라디같은 음이온성 4급질소 원자로서 존재한다.)Where R + represents anionic sodium atom (Na + ) (II) or lysine (III), arginine (IV), glucamine (V) or meglumine (VI), and (III) (IV) (V) and It exists as an anionic quaternary nitrogen atom, such as the amine radi of (VI).) ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR860011424A 1986-01-03 1986-12-29 4,5-diphenyl-2-oxazole manufacturing method of water-soluble derivative of propionic acid KR870007143A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT19005/86A IT1204751B (en) 1986-01-03 1986-01-03 WATER SOLUBLE ACID DERIVATIVES 4,5 -DIPHENYL-2 -XSAZOLPROPIONIC, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS
IT19005 1986-01-03

Publications (1)

Publication Number Publication Date
KR870007143A true KR870007143A (en) 1987-08-17

Family

ID=11153779

Family Applications (1)

Application Number Title Priority Date Filing Date
KR860011424A KR870007143A (en) 1986-01-03 1986-12-29 4,5-diphenyl-2-oxazole manufacturing method of water-soluble derivative of propionic acid

Country Status (6)

Country Link
JP (1) JPS6322085A (en)
KR (1) KR870007143A (en)
DE (1) DE3700158A1 (en)
ES (1) ES2003195A6 (en)
IT (1) IT1204751B (en)
YU (1) YU45310B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1129429C (en) * 1996-05-20 2003-12-03 G·D·瑟尔公司 potassium, sodium and tris oxaprozin salt pharmaceutical formulations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL28803A (en) * 1966-11-18 1974-05-16 Wyeth John & Brother Ltd Oxazole and thiazole compounds,their preparation and pharmaceutical compositions containing them
JPS4938267A (en) * 1972-08-18 1974-04-09
ES412429A1 (en) * 1973-03-08 1976-01-01 Gallardo Antonio Sa Soluble salt of a cephalosporin
IN160683B (en) * 1981-06-01 1987-07-25 Pfizer

Also Published As

Publication number Publication date
JPS6322085A (en) 1988-01-29
IT1204751B (en) 1989-03-10
IT8619005A0 (en) 1986-01-03
YU45310B (en) 1992-05-28
DE3700158A1 (en) 1987-07-23
YU37486A (en) 1988-02-29
ES2003195A6 (en) 1988-10-16

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E601 Decision to refuse application