ES412429A1 - Soluble salt of a cephalosporin - Google Patents

Soluble salt of a cephalosporin

Info

Publication number
ES412429A1
ES412429A1 ES412429A ES412429A ES412429A1 ES 412429 A1 ES412429 A1 ES 412429A1 ES 412429 A ES412429 A ES 412429A ES 412429 A ES412429 A ES 412429A ES 412429 A1 ES412429 A1 ES 412429A1
Authority
ES
Spain
Prior art keywords
heteroaryl
cephalosporin
see formula
soluble salt
ooc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES412429A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antonio Gallardo SA
Original Assignee
Antonio Gallardo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antonio Gallardo SA filed Critical Antonio Gallardo SA
Priority to ES412429A priority Critical patent/ES412429A1/en
Priority to DE2411260A priority patent/DE2411260A1/en
Priority to FR7409584A priority patent/FR2220533B1/fr
Priority to GB1046474A priority patent/GB1445803A/en
Priority to JP49027013A priority patent/JPS5029726A/ja
Publication of ES412429A1 publication Critical patent/ES412429A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure for obtaining antibiotic salts with amino acids of a basic nature, which correspond to the structure: **(See formula)** essentially lysine, histidine and arginine, where R1 is an aryl, heteroaryl or heteroaryl-thio radical, of structure: **(See formula)** R2 is H or NH2, and R3 is H or -OOC-CH3 characterized in that the reaction is carried out using, as solvents, water, methanol, ethanol, acetone, dimethylformamide, dimethyl sulfoxide or a mixture thereof and at a temperature comprised between 0º and 60ºC. (Machine-translation by Google Translate, not legally binding)
ES412429A 1973-03-08 1973-03-08 Soluble salt of a cephalosporin Expired ES412429A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES412429A ES412429A1 (en) 1973-03-08 1973-03-08 Soluble salt of a cephalosporin
DE2411260A DE2411260A1 (en) 1973-03-08 1974-03-08 PROCESS FOR THE OBTAINING SALT OF ANTIBIOTICS WITH NATURAL AMINO ACIDS
FR7409584A FR2220533B1 (en) 1973-03-08 1974-03-08
GB1046474A GB1445803A (en) 1973-03-08 1974-03-08 Soluble salt of a cephalosporin
JP49027013A JPS5029726A (en) 1973-03-08 1974-03-08

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES412429A ES412429A1 (en) 1973-03-08 1973-03-08 Soluble salt of a cephalosporin

Publications (1)

Publication Number Publication Date
ES412429A1 true ES412429A1 (en) 1976-01-01

Family

ID=8463621

Family Applications (1)

Application Number Title Priority Date Filing Date
ES412429A Expired ES412429A1 (en) 1973-03-08 1973-03-08 Soluble salt of a cephalosporin

Country Status (5)

Country Link
JP (1) JPS5029726A (en)
DE (1) DE2411260A1 (en)
ES (1) ES412429A1 (en)
FR (1) FR2220533B1 (en)
GB (1) GB1445803A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2308368A1 (en) * 1975-04-21 1976-11-19 Gallardo Antonio Sa Lysine salt of cephalexin - effect when administered parenterally as well as orally
US4235900A (en) * 1978-11-15 1980-11-25 E. R. Squibb & Sons, Inc. Cephradine compositions
IT1148778B (en) * 1980-04-01 1986-12-03 Dob Far Spa SALTS CEFADROVIXIL WITH AMINO ACIDS
IT1141406B (en) * 1980-04-01 1986-10-01 Dob Far Spa SALTS OF CEPHAPIRINE WITH AMINO ACIDS
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
IT1204751B (en) * 1986-01-03 1989-03-10 Therapicon Srl WATER SOLUBLE ACID DERIVATIVES 4,5 -DIPHENYL-2 -XSAZOLPROPIONIC, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS
JP2520385B2 (en) * 1989-01-30 1996-07-31 パーザー ファーマスーティカル カンパニー リミテッド 3-Substituent-7-Substituted amino group Process for producing alkali metal salt of cephalosporanaic acid derivative

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984403A (en) * 1972-06-30 1976-10-05 Takeda Chemical Industries, Ltd. Arginine and lysine salts of acid cephalosporins

Also Published As

Publication number Publication date
DE2411260A1 (en) 1974-09-12
FR2220533B1 (en) 1978-11-10
FR2220533A1 (en) 1974-10-04
GB1445803A (en) 1976-08-11
JPS5029726A (en) 1975-03-25

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19950403