KR870000355A - 글루타치온 모노알킬 에스테르 황산염의 제조방법 - Google Patents

글루타치온 모노알킬 에스테르 황산염의 제조방법 Download PDF

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Publication number
KR870000355A
KR870000355A KR1019860004455A KR860004455A KR870000355A KR 870000355 A KR870000355 A KR 870000355A KR 1019860004455 A KR1019860004455 A KR 1019860004455A KR 860004455 A KR860004455 A KR 860004455A KR 870000355 A KR870000355 A KR 870000355A
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KR
South Korea
Prior art keywords
glutathione
sulfates
ester sulfate
monoalkyl ester
glutathione monoalkyl
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KR1019860004455A
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English (en)
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KR930005992B1 (ko
Inventor
요시노부 나가노
Original Assignee
야마노우찌 세이야꾸 가부시끼가이샤
모리오까 시게오
야마노우찌 세아야꾸 가부시끼 가이샤
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Application filed by 야마노우찌 세이야꾸 가부시끼가이샤, 모리오까 시게오, 야마노우찌 세아야꾸 가부시끼 가이샤 filed Critical 야마노우찌 세이야꾸 가부시끼가이샤
Publication of KR870000355A publication Critical patent/KR870000355A/ko
Application granted granted Critical
Publication of KR930005992B1 publication Critical patent/KR930005992B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

내용 없음

Description

글루타치온 모노알킬 에스테르 황산염의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. r-L-글루타밀-L-시스테이닐글리신을 황산 존재하에, 일반식 R-OH(여기에서, R는 하기한 바와 같음)의 알코올과 반응시킴을 특징으로 하는 하기 일반식으로 표시되는 글루타치온 모노알킬 에스테르 황산염의 제조방법.
    (식 중, R는 탄소 원자수가 1 내지 10개인 알킬기임).
  2. 제1항에 있어서, 반응을 r-L-글루타밀-L-시스테이닐 글리신에 기초해서 2내지 4 당량비의 황산존재하에 행하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019860004455A 1985-06-07 1986-06-05 글루타티온 모노알킬 에스테르 황산염의 제조방법 KR930005992B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP12393085 1985-06-07
JP60-123930 1985-06-07
JP123930 1999-04-30

Publications (2)

Publication Number Publication Date
KR870000355A true KR870000355A (ko) 1987-02-18
KR930005992B1 KR930005992B1 (ko) 1993-07-01

Family

ID=14872863

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860004455A KR930005992B1 (ko) 1985-06-07 1986-06-05 글루타티온 모노알킬 에스테르 황산염의 제조방법

Country Status (7)

Country Link
US (1) US4709013A (ko)
EP (1) EP0204589B1 (ko)
JP (1) JPH0742308B2 (ko)
KR (1) KR930005992B1 (ko)
AT (1) ATE69238T1 (ko)
DE (1) DE3682330D1 (ko)
ES (1) ES8707261A1 (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879370A (en) * 1983-12-02 1989-11-07 Cornell Research Foundation, Inc. Glutathione delivery system
US4968671A (en) * 1987-11-26 1990-11-06 Yamanouchi Pharmaceutical Co., Ltd. Therapeutic agents for ischemic heart diseases
US4883862A (en) * 1988-04-13 1989-11-28 Albert Einstein College Of Medicine - Of Yeshiva University Mercaptosuccinyl glycyl-glycyl-glycine a complex thereof with Tc-99m, and methods of making the same
US5110796A (en) * 1988-12-09 1992-05-05 Yamanouchi Pharmaceutical Co., Ltd. Prophylactic and therapeutic agents for cataracts
US5093478A (en) * 1989-07-14 1992-03-03 Cornell Research Foundation, Inc. Preparing glutathione monoesters
US5464825A (en) * 1991-03-14 1995-11-07 Cornell Research Foundation, Inc. Raising glutathione equivalent levels using N-acyl glutathione monoesters
NL9102143A (nl) * 1991-12-20 1993-07-16 Dsm Nv Bereiding van oligopeptide- of aminozuur-alkylester. hcl-zouten.
JPH08509737A (ja) * 1993-05-03 1996-10-15 コーネル・リサーチ・ファウンデーション・インコーポレイテッド グルタチオンジエステルの使用
JPH09301996A (ja) * 1996-05-09 1997-11-25 Kyowa Hakko Kogyo Co Ltd グルタチオンモノエステルスルホン酸塩
US5780489A (en) * 1996-08-21 1998-07-14 Brooks; Benjamin Rix Method for treating amyotrophic lateral sclerosis
US5756823A (en) * 1996-09-05 1998-05-26 Kyowa Hakko Kogyo Co., Ltd. Glutathione monoester sulfonate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3882097A (en) * 1969-08-13 1975-05-06 Merck & Co Inc {60 -Methyl glutathione, analogs thereof, intermediates therefore and processes for their preparation
JPS6115870A (ja) * 1984-06-29 1986-01-23 Yamanouchi Pharmaceut Co Ltd グルタチオン　モノエステルの製造法

Also Published As

Publication number Publication date
EP0204589A3 (en) 1988-09-21
ES555837A0 (es) 1987-07-16
DE3682330D1 (de) 1991-12-12
JPH0742308B2 (ja) 1995-05-10
EP0204589B1 (en) 1991-11-06
JPS6289695A (ja) 1987-04-24
ATE69238T1 (de) 1991-11-15
ES8707261A1 (es) 1987-07-16
EP0204589A2 (en) 1986-12-10
KR930005992B1 (ko) 1993-07-01
US4709013A (en) 1987-11-24

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