KR840003626A - 신규 크로마논 유도체의 제법 - Google Patents

신규 크로마논 유도체의 제법 Download PDF

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Publication number
KR840003626A
KR840003626A KR1019830000453A KR830000453A KR840003626A KR 840003626 A KR840003626 A KR 840003626A KR 1019830000453 A KR1019830000453 A KR 1019830000453A KR 830000453 A KR830000453 A KR 830000453A KR 840003626 A KR840003626 A KR 840003626A
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KR
South Korea
Prior art keywords
general formula
compound represented
novel
reacting
ring
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KR1019830000453A
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English (en)
Inventor
가오루 오까모도 (외 2)
Original Assignee
고니시 직우에몬
니혼 소오기 세이야꾸 가부시기 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 고니시 직우에몬, 니혼 소오기 세이야꾸 가부시기 가이샤 filed Critical 고니시 직우에몬
Publication of KR840003626A publication Critical patent/KR840003626A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

내용 없음

Description

신규 크로마논 유도체의 제법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (22)

  1. 일반식(Ⅰ)로서 표시되는 신규 크로마논 유도체를 제조함에 있어서,
  3. (R1,R2,R4및 R5는 수소 또는 저급알킬기를 표시하고, R3는 수소 또는 할로겐을 표시하며, n은 0 또는 1이다.) 일반식(Ⅱ)로서 표시되는 화합물에
  5. (Ra는 수소, 저급 알킬기 또는 -CHR2-COOR1Rb는 수소 또는 저급알킬기를 표시한다.)
  6. ㄱ) 일반식(Ⅲ)으로서 표시되는 카르본산 혹은 그 반응성 유도체를 반응시켜
  8. 일반식(Ⅳ)로서 표시되는 화합물로 하고, 그것을 폐환시키든가,
  10. ㄴ) 일반식(Ⅴ)로서 표시되는 화합물을 반응시켜
  12. (X1, X2는 할로겐을 표시한다.)
  13. 일반식(Ⅵ)로서 표시되는 화합물로 하고, 그것을 폐환시키든가,
  15. ㄱ) -프로피오락톤을 반응시켜 일반식(Ⅶ)으로서 표시되는 화합물로하고, 이것을 폐환시키든가,
  17. ㄹ) 일반식(Ⅷ)로서 표시되는 화합물을 반응시킨 후 폐환하고, 또 다시 환원하여
  19. 일반식(Ⅸ)로서 표시되는 화합물로하며, 이것을 산화하는 것을
  21. 특징으로 하는 신규 크로마논 유도체의 제법.
  22. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019830000453A 1982-02-05 1983-02-05 신규 크로마논 유도체의 제법 KR840003626A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP57-17971 1982-02-05
JP57017971A JPS58135877A (ja) 1982-02-05 1982-02-05 新規クロマノン誘導体及び該化合物を含有する医薬組成物

Publications (1)

Publication Number Publication Date
KR840003626A true KR840003626A (ko) 1984-09-15

Family

ID=11958611

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830000453A KR840003626A (ko) 1982-02-05 1983-02-05 신규 크로마논 유도체의 제법

Country Status (6)

Country Link
EP (1) EP0087858A1 (ko)
JP (1) JPS58135877A (ko)
KR (1) KR840003626A (ko)
AU (1) AU1088883A (ko)
DK (1) DK38483A (ko)
ES (1) ES519546A0 (ko)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1077066A (en) * 1963-09-10 1967-07-26 Benger Lab Ltd Improvements in or relating to the synthesis of chromanones
GB1499323A (en) * 1974-03-22 1978-02-01 Fisons Ltd 6-substituted chromones and chromanones
US4151179A (en) * 1975-03-12 1979-04-24 Fisons Limited 2-(4H-1-Benzopyran-6-yl)propionic acids
IT1093805B (it) * 1978-01-31 1985-07-26 Erba Carlo Spa Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione

Also Published As

Publication number Publication date
DK38483D0 (da) 1983-02-01
ES8403471A1 (es) 1984-03-16
JPS58135877A (ja) 1983-08-12
ES519546A0 (es) 1984-03-16
EP0087858A1 (en) 1983-09-07
AU1088883A (en) 1983-08-11
DK38483A (da) 1983-08-06

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