KR840001955A - 4-(3-메틸-2-부테닐)-1,2-디페닐-3,5-디옥소피라졸리딘의 제조방법 - Google Patents
4-(3-메틸-2-부테닐)-1,2-디페닐-3,5-디옥소피라졸리딘의 제조방법 Download PDFInfo
- Publication number
- KR840001955A KR840001955A KR1019820004867A KR820004867A KR840001955A KR 840001955 A KR840001955 A KR 840001955A KR 1019820004867 A KR1019820004867 A KR 1019820004867A KR 820004867 A KR820004867 A KR 820004867A KR 840001955 A KR840001955 A KR 840001955A
- Authority
- KR
- South Korea
- Prior art keywords
- dioxopyrazolidine
- diphenyl
- methyl
- palladium
- bis
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 8
- RBBWCVQDXDFISW-UHFFFAOYSA-N Feprazone Chemical compound O=C1C(CC=C(C)C)C(=O)N(C=2C=CC=CC=2)N1C1=CC=CC=C1 RBBWCVQDXDFISW-UHFFFAOYSA-N 0.000 title 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical group [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims 5
- XDPKQGKEOCYMQC-UHFFFAOYSA-N 1,2-diphenylpyrazolidine-3,5-dione Chemical compound O=C1CC(=O)N(C=2C=CC=CC=2)N1C1=CC=CC=C1 XDPKQGKEOCYMQC-UHFFFAOYSA-N 0.000 claims 2
- XTHFKEDIFFGKHM-UHFFFAOYSA-N Dimethoxyethane Chemical compound COCCOC XTHFKEDIFFGKHM-UHFFFAOYSA-N 0.000 claims 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims 2
- 239000003054 catalyst Substances 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- 229910052763 palladium Inorganic materials 0.000 claims 2
- NFHFRUOZVGFOOS-UHFFFAOYSA-N palladium;triphenylphosphane Chemical group [Pd].C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 NFHFRUOZVGFOOS-UHFFFAOYSA-N 0.000 claims 2
- UKSZBOKPHAQOMP-SVLSSHOZSA-N (1e,4e)-1,5-diphenylpenta-1,4-dien-3-one;palladium Chemical compound [Pd].C=1C=CC=CC=1\C=C\C(=O)\C=C\C1=CC=CC=C1.C=1C=CC=CC=1\C=C\C(=O)\C=C\C1=CC=CC=C1 UKSZBOKPHAQOMP-SVLSSHOZSA-N 0.000 claims 1
- QFMZQPDHXULLKC-UHFFFAOYSA-N 1,2-bis(diphenylphosphino)ethane Chemical compound C=1C=CC=CC=1P(C=1C=CC=CC=1)CCP(C=1C=CC=CC=1)C1=CC=CC=C1 QFMZQPDHXULLKC-UHFFFAOYSA-N 0.000 claims 1
- OTMSDBZUPAUEDD-UHFFFAOYSA-N Ethane Chemical compound CC OTMSDBZUPAUEDD-UHFFFAOYSA-N 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- XXIKYCPRDXIMQM-UHFFFAOYSA-N Isopentenyl acetate Chemical compound CC(C)=CCOC(C)=O XXIKYCPRDXIMQM-UHFFFAOYSA-N 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 150000001447 alkali salts Chemical class 0.000 claims 1
- 229910003002 lithium salt Inorganic materials 0.000 claims 1
- 159000000002 lithium salts Chemical class 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/28—Two oxygen or sulfur atoms
- C07D231/30—Two oxygen or sulfur atoms attached in positions 3 and 5
- C07D231/32—Oxygen atoms
- C07D231/34—Oxygen atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT24772/81A IT1168184B (it) | 1981-10-29 | 1981-10-29 | Processo per la preparazione della 4-(3-metil-2-butanile)-1,2-difenil-3,5 dichetopirazolidina |
| IT24772A | 1981-10-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR840001955A true KR840001955A (ko) | 1984-06-07 |
Family
ID=11214682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019820004867A KR840001955A (ko) | 1981-10-29 | 1982-10-28 | 4-(3-메틸-2-부테닐)-1,2-디페닐-3,5-디옥소피라졸리딘의 제조방법 |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5888365A (es) |
| KR (1) | KR840001955A (es) |
| AR (1) | AR231832A1 (es) |
| AT (1) | AT379151B (es) |
| CA (1) | CA1179354A (es) |
| CH (1) | CH651555A5 (es) |
| DK (1) | DK477882A (es) |
| ES (1) | ES516902A0 (es) |
| FI (1) | FI823545L (es) |
| FR (1) | FR2515646B1 (es) |
| GB (1) | GB2108125B (es) |
| GR (1) | GR77724B (es) |
| IT (1) | IT1168184B (es) |
| NL (1) | NL8204170A (es) |
| NO (1) | NO823596L (es) |
| PH (1) | PH19644A (es) |
| PT (1) | PT75755B (es) |
| SE (1) | SE8206143L (es) |
| YU (1) | YU240282A (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107778247A (zh) * | 2016-08-30 | 2018-03-09 | 天津太平洋制药有限公司 | 一种非普拉宗及其中间体的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1301857A (es) * | 1969-06-27 | 1973-01-04 |
-
1981
- 1981-10-29 IT IT24772/81A patent/IT1168184B/it active
-
1982
- 1982-10-07 AT AT0370382A patent/AT379151B/de not_active IP Right Cessation
- 1982-10-14 PH PH27984A patent/PH19644A/en unknown
- 1982-10-18 FI FI823545A patent/FI823545L/fi not_active Application Discontinuation
- 1982-10-26 GR GR69645A patent/GR77724B/el unknown
- 1982-10-26 YU YU02402/82A patent/YU240282A/xx unknown
- 1982-10-26 CH CH6249/82A patent/CH651555A5/de not_active IP Right Cessation
- 1982-10-27 PT PT75755A patent/PT75755B/pt unknown
- 1982-10-28 KR KR1019820004867A patent/KR840001955A/ko unknown
- 1982-10-28 DK DK477882A patent/DK477882A/da not_active Application Discontinuation
- 1982-10-28 ES ES516902A patent/ES516902A0/es active Granted
- 1982-10-28 JP JP57189954A patent/JPS5888365A/ja active Pending
- 1982-10-28 NO NO823596A patent/NO823596L/no unknown
- 1982-10-28 CA CA000414428A patent/CA1179354A/en not_active Expired
- 1982-10-28 SE SE8206143A patent/SE8206143L/xx not_active Application Discontinuation
- 1982-10-28 GB GB08230767A patent/GB2108125B/en not_active Expired
- 1982-10-28 NL NL8204170A patent/NL8204170A/nl not_active Application Discontinuation
- 1982-10-29 FR FR8218200A patent/FR2515646B1/fr not_active Expired
- 1982-10-29 AR AR291152A patent/AR231832A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| NL8204170A (nl) | 1983-05-16 |
| GB2108125B (en) | 1985-03-20 |
| CH651555A5 (de) | 1985-09-30 |
| DK477882A (da) | 1983-04-30 |
| FR2515646B1 (fr) | 1986-02-14 |
| JPS5888365A (ja) | 1983-05-26 |
| SE8206143D0 (sv) | 1982-10-28 |
| ES8308855A1 (es) | 1983-10-01 |
| AR231832A1 (es) | 1985-03-29 |
| CA1179354A (en) | 1984-12-11 |
| GB2108125A (en) | 1983-05-11 |
| PT75755A (en) | 1982-11-01 |
| FR2515646A1 (fr) | 1983-05-06 |
| NO823596L (no) | 1983-05-02 |
| FI823545A0 (fi) | 1982-10-18 |
| IT8124772A0 (it) | 1981-10-29 |
| PH19644A (en) | 1986-06-04 |
| FI823545L (fi) | 1983-04-30 |
| AT379151B (de) | 1985-11-25 |
| SE8206143L (sv) | 1983-04-30 |
| PT75755B (en) | 1985-11-20 |
| YU240282A (en) | 1985-03-20 |
| GR77724B (es) | 1984-09-25 |
| IT1168184B (it) | 1987-05-20 |
| ES516902A0 (es) | 1983-10-01 |
| ATA370382A (de) | 1985-04-15 |
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