KR830009067A - Process for preparing 2-substituted hydroxyimino-2 (5-amino-1,2,4-thiadiazol-3-yl) acetic acid or salts thereof and intermediates thereof - Google Patents

Process for preparing 2-substituted hydroxyimino-2 (5-amino-1,2,4-thiadiazol-3-yl) acetic acid or salts thereof and intermediates thereof Download PDF

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Publication number
KR830009067A
KR830009067A KR1019820000972A KR820000972A KR830009067A KR 830009067 A KR830009067 A KR 830009067A KR 1019820000972 A KR1019820000972 A KR 1019820000972A KR 820000972 A KR820000972 A KR 820000972A KR 830009067 A KR830009067 A KR 830009067A
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KR
South Korea
Prior art keywords
substituted
thiadiazol
intermediates
salts
amino
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Application number
KR1019820000972A
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Korean (ko)
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KR880001762B1 (en
Inventor
쯔도무 데라지
가즈오 사까네
지로오 고도오
Original Assignee
후지사와 도모 기찌로오
후지사와 야꾸힝 고교 가부시기 가이샤
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Publication of KR830009067A publication Critical patent/KR830009067A/en
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Publication of KR880001762B1 publication Critical patent/KR880001762B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

내용 없음No content

Description

2-치환된 하이드록시이미노-2(5-아미노-1,2,4-티아디아졸-3-일) 초산 혹은 그것의 염 그리고 그것의 중간생성물의 제조방법Process for preparing 2-substituted hydroxyimino-2 (5-amino-1,2,4-thiadiazol-3-yl) acetic acid or salts thereof and intermediates thereof

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (1)

하기 구조식(II) 화합물을 가수분해하는 것으로서, R1이 카르복실로 치환된 저급알킬인 경우에, R1이 보호된 카르복실로 치환된 저급 알킬인 화합물로 전환됨을 특징으로 하는 하기 구조식(I) 화합물의 제조방법.The following structural formula (I) is characterized in that, when R 1 is lower alkyl substituted with carboxyl, R 1 is converted to lower alkyl substituted with protected carboxyl. ) Preparation of the compound. 상기 구조식에서 R1은 적당한 치환제로 치환되는 저급알킬, 저급알케닐,저급알키닐, 싸이클로알킬, 싸이클로(저급)알케닐, 적당한 치환체로 치환되는 아릴, 유황 함유하며 옥소그룹으로 치환된 이종 5원환그룹, 혹은 그것의 염이다.In the above formula, R 1 is lower alkyl, lower alkenyl, lower alkynyl, cycloalkyl, cyclo (lower) alkenyl substituted with a suitable substituent, aryl substituted with a suitable substituent, sulfur-containing, hetero five-membered ring substituted with oxo group Group, or a salt thereof. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR8200972A 1981-03-06 1982-03-06 Processes for preparing 2-substituted hydroxyimino-2-(5-amino-1,2,4-thiadiazol-3-yl)acetic or tis salt KR880001762B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8107134 1981-03-06
GB8107134 1981-03-06

Publications (2)

Publication Number Publication Date
KR830009067A true KR830009067A (en) 1983-12-17
KR880001762B1 KR880001762B1 (en) 1988-09-12

Family

ID=10520204

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8200972A KR880001762B1 (en) 1981-03-06 1982-03-06 Processes for preparing 2-substituted hydroxyimino-2-(5-amino-1,2,4-thiadiazol-3-yl)acetic or tis salt

Country Status (3)

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JP (2) JPS57158769A (en)
KR (1) KR880001762B1 (en)
GB (1) GB2094794B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0717622B2 (en) * 1986-06-05 1995-03-01 エーザイ株式会社 Thiadiazolylacetamide derivative
JPH0625187B2 (en) * 1986-12-10 1994-04-06 エーザイ株式会社 Thiadiazole derivative
JPH0699449B2 (en) * 1988-03-16 1994-12-07 エーザイ株式会社 Synthetic intermediate of cephem derivative
IE902556A1 (en) * 1989-07-19 1991-02-27 Fujisawa Pharmaceutical Co Processes for preparing 2-substituted¹hydroxyimino-2-(5-amino-1,2,4-thiadiazol-3-yl) acetic acid¹or its salts
CN101962371B (en) * 2010-10-13 2013-07-24 浙江工业大学 Method for preparing ceftobiprole side chain acid and key intermediate thereof
CN102093266B (en) * 2011-01-21 2013-07-24 蚌埠丰原医药科技发展有限公司 Method for preparing O-tosyl-2-carbamoyl-2-methoxyl-imido-acetamido-oxime
JP6327754B2 (en) * 2013-06-21 2018-05-23 クミアイ化学工業株式会社 Process for producing 2-amino-2-hydroxyimino-N-alkoxyacetimidoylcyanide and its intermediate
CN103804321B (en) * 2014-02-18 2016-03-02 陕西思尔生物科技有限公司 (Z) preparation method of-5-amino-α-(ethoxy imino)-1,2,4-thiadiazoles-3-acetic acid
CN104177408B (en) * 2014-09-12 2016-09-07 衡水衡林生物科技有限公司 (Z) preparation method of-2-(5-dichlor-phosphoryl amino-1,2,4-thiadiazoles-3-base)-2-ethoxyimino chloroacetic chloride
CN105330612B (en) * 2015-11-04 2018-04-03 上海泰坦科技股份有限公司 The synthesis technique of 2 (base of 5 amino, 1,2,4 thiadiazoles 3) 2 methoxyimino acetic acid
WO2018053587A1 (en) * 2016-09-21 2018-03-29 Vectus Biosystems Limited Compositions for the treatment of hypertension and/or fibrosis
CN110713443B (en) 2018-07-13 2022-01-28 沈阳中化农药化工研发有限公司 Process for preparing malononitrile oxime ether compounds and intermediate compounds
CN109096224A (en) * 2018-09-27 2018-12-28 陕西思尔生物科技有限公司 A kind of synthetic method of Ceftobiprole side-chain acid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS576425B2 (en) * 1972-06-19 1982-02-04
JPS4924963A (en) * 1972-06-27 1974-03-05
JPS5537556B2 (en) * 1973-12-27 1980-09-29
HU183006B (en) * 1978-12-29 1984-04-28 Fujisawa Pharmaceutical Co Process for producing 7-substituted-3-cepheme- and cephame-4-carboxylic acid derivatives

Also Published As

Publication number Publication date
JPH0476990B2 (en) 1992-12-07
GB2094794B (en) 1985-02-20
JPH0629272B2 (en) 1994-04-20
KR880001762B1 (en) 1988-09-12
JPH05186447A (en) 1993-07-27
GB2094794A (en) 1982-09-22
JPS57158769A (en) 1982-09-30

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