KR830004291A - 3-아실아미노-5-[4(또는 3)-피리디닐-2(1h)-피리디논 또는 그의 산부가염의 제조방법 - Google Patents
3-아실아미노-5-[4(또는 3)-피리디닐-2(1h)-피리디논 또는 그의 산부가염의 제조방법 Download PDFInfo
- Publication number
- KR830004291A KR830004291A KR1019800004918A KR800004918A KR830004291A KR 830004291 A KR830004291 A KR 830004291A KR 1019800004918 A KR1019800004918 A KR 1019800004918A KR 800004918 A KR800004918 A KR 800004918A KR 830004291 A KR830004291 A KR 830004291A
- Authority
- KR
- South Korea
- Prior art keywords
- pyridinone
- pyridinyl
- acid addition
- addition salts
- acylamino
- Prior art date
Links
- 239000002253 acid Substances 0.000 title claims 4
- 150000003839 salts Chemical class 0.000 title claims 4
- -1 2-acetoxypropanoyl Chemical group 0.000 claims 5
- 125000002339 acetoacetyl group Chemical group O=C([*])C([H])([H])C(=O)C([H])([H])[H] 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000012458 free base Substances 0.000 claims 1
- UBQKCCHYAOITMY-UHFFFAOYSA-N pyridin-2-ol Chemical compound OC1=CC=CC=N1 UBQKCCHYAOITMY-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (3)
- 3-아미노-5-[4(또는 3)-피리디닐]-2(1H)-피리디논을 아실을 내는 아실화제와 반응시키고, 필요하다면, 얻어진 유리염기를 그의 산부가염으로 전환시키는 것을 특징으로 하는 3-아실아미노-5-[4(또는 3)-피리디닐]-2(1H)-피리디논의 제조방법(여기서 아실은 2-아세톡시프로파노일, 아세토아세틸 또는 아세톡시아세틸, 또는 그의 산부가염이다).
- 3-(2-아세톡시프로파노일아미노)-5-14-피리디닐)-2(1H)-피리디논 또는 3-(아세토아세틸아미노)-5-(4-피리디닐)-2(1H)-피리디논 또는 그의 산부가염이 제조되는 것을 특징으로 하는 청구범위 1에 의한 방법.
- ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/106,764 US4271168A (en) | 1979-12-26 | 1979-12-26 | Selected 3-acylamino-5-[4(or 3)-pyridinyl]-2(1H)-pyridinones |
US106764 | 1993-08-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR830004291A true KR830004291A (ko) | 1983-07-09 |
Family
ID=22313122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019800004918A KR830004291A (ko) | 1979-12-26 | 1980-12-24 | 3-아실아미노-5-[4(또는 3)-피리디닐-2(1h)-피리디논 또는 그의 산부가염의 제조방법 |
Country Status (25)
Country | Link |
---|---|
US (1) | US4271168A (ko) |
JP (1) | JPS56103164A (ko) |
KR (1) | KR830004291A (ko) |
AR (1) | AR230435A1 (ko) |
AT (1) | AT373876B (ko) |
AU (1) | AU6556680A (ko) |
BE (1) | BE886766A (ko) |
CA (1) | CA1131231A (ko) |
DE (1) | DE3048635A1 (ko) |
DK (1) | DK550480A (ko) |
ES (1) | ES498144A0 (ko) |
FI (1) | FI803973L (ko) |
FR (1) | FR2472563A1 (ko) |
GB (1) | GB2066251B (ko) |
IE (1) | IE50523B1 (ko) |
IL (1) | IL61690A (ko) |
IT (1) | IT1134860B (ko) |
LU (1) | LU83032A1 (ko) |
NL (1) | NL8006824A (ko) |
NO (1) | NO803911L (ko) |
NZ (1) | NZ195878A (ko) |
PH (1) | PH15974A (ko) |
PT (1) | PT72264B (ko) |
SE (1) | SE8009134L (ko) |
ZA (1) | ZA807864B (ko) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS587411A (ja) * | 1981-07-07 | 1983-01-17 | Mitsui Toatsu Chem Inc | 薄肉射出成形用プロピレン/エチレン共重合体の製造方法 |
US4432979A (en) * | 1981-10-26 | 1984-02-21 | William H. Rorer, Inc. | Pyridone compounds |
BE896678A (fr) * | 1982-05-18 | 1983-11-07 | Sandoz Sa | Nouveaux derives de la 2 (1h)-pyridinone, leur preparation et leur utilisation comme medicaments. |
IT8367883A0 (it) * | 1982-08-23 | 1983-08-22 | Rorer Int Overseas | Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche |
US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
RU2423351C2 (ru) * | 2004-12-16 | 2011-07-10 | Вертекс Фармасьютикалз Инкорпорейтед | Пирид-2-оны, применимые как ингибиторы протеинкиназ семейства тес для лечения воспалительных, пролиферативных и иммунологически-опосредованных заболеваний |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
US4004012A (en) * | 1975-10-14 | 1977-01-18 | Sterling Drug Inc. | 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones |
-
1979
- 1979-12-26 US US06/106,764 patent/US4271168A/en not_active Expired - Lifetime
-
1980
- 1980-12-11 IL IL61690A patent/IL61690A/xx unknown
- 1980-12-12 IE IE2619/80A patent/IE50523B1/en unknown
- 1980-12-16 NL NL8006824A patent/NL8006824A/nl not_active Application Discontinuation
- 1980-12-17 ZA ZA00807864A patent/ZA807864B/xx unknown
- 1980-12-18 NZ NZ195878A patent/NZ195878A/xx unknown
- 1980-12-18 PH PH25005A patent/PH15974A/en unknown
- 1980-12-19 AU AU65566/80A patent/AU6556680A/en not_active Abandoned
- 1980-12-19 FI FI803973A patent/FI803973L/fi not_active Application Discontinuation
- 1980-12-19 BE BE1/10084A patent/BE886766A/fr not_active IP Right Cessation
- 1980-12-22 PT PT72264A patent/PT72264B/pt unknown
- 1980-12-22 FR FR8027218A patent/FR2472563A1/fr active Pending
- 1980-12-22 IT IT26876/80A patent/IT1134860B/it active
- 1980-12-22 NO NO803911A patent/NO803911L/no unknown
- 1980-12-23 GB GB8041225A patent/GB2066251B/en not_active Expired
- 1980-12-23 AT AT0629380A patent/AT373876B/de not_active IP Right Cessation
- 1980-12-23 DK DK550480A patent/DK550480A/da not_active Application Discontinuation
- 1980-12-23 AR AR283770A patent/AR230435A1/es active
- 1980-12-23 SE SE8009134A patent/SE8009134L/xx not_active Application Discontinuation
- 1980-12-23 CA CA367,452A patent/CA1131231A/en not_active Expired
- 1980-12-23 DE DE19803048635 patent/DE3048635A1/de not_active Withdrawn
- 1980-12-23 LU LU83032A patent/LU83032A1/fr unknown
- 1980-12-24 ES ES498144A patent/ES498144A0/es active Granted
- 1980-12-24 KR KR1019800004918A patent/KR830004291A/ko unknown
- 1980-12-26 JP JP18947780A patent/JPS56103164A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
FI803973L (fi) | 1981-06-27 |
GB2066251A (en) | 1981-07-08 |
ZA807864B (en) | 1981-12-30 |
IT1134860B (it) | 1986-08-20 |
SE8009134L (sv) | 1981-06-27 |
AT373876B (de) | 1984-02-27 |
IT8026876A0 (it) | 1980-12-22 |
PH15974A (en) | 1983-05-11 |
LU83032A1 (fr) | 1981-07-23 |
FR2472563A1 (fr) | 1981-07-03 |
PT72264B (en) | 1981-11-05 |
IL61690A (en) | 1983-11-30 |
NZ195878A (en) | 1982-11-23 |
AU6556680A (en) | 1981-07-02 |
IE802619L (en) | 1981-06-26 |
DK550480A (da) | 1981-06-27 |
IL61690A0 (en) | 1981-01-30 |
NO803911L (no) | 1981-06-29 |
AR230435A1 (es) | 1984-04-30 |
US4271168A (en) | 1981-06-02 |
CA1131231A (en) | 1982-09-07 |
PT72264A (en) | 1981-01-01 |
ES8201136A1 (es) | 1981-12-01 |
ATA629380A (de) | 1983-07-15 |
JPS56103164A (en) | 1981-08-18 |
DE3048635A1 (de) | 1981-09-17 |
NL8006824A (nl) | 1981-07-16 |
GB2066251B (en) | 1983-10-19 |
ES498144A0 (es) | 1981-12-01 |
IE50523B1 (en) | 1986-04-30 |
BE886766A (fr) | 1981-06-19 |
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