KR20250012721A - 클로라이드 채널의 표적된 발현 및 이의 사용 방법 - Google Patents
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| US201662378509P | 2016-08-23 | 2016-08-23 | |
| US62/378,509 | 2016-08-23 | ||
| PCT/US2016/054199 WO2017058926A1 (en) | 2015-10-01 | 2016-09-28 | Targeted expression of chloride channels and methods of use thereof |
| KR1020187012245A KR20180072713A (ko) | 2015-10-01 | 2016-09-28 | 클로라이드 채널의 표적된 발현 및 이의 사용 방법 |
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| US20220008557A1 (en) * | 2018-11-14 | 2022-01-13 | Flagship Pioneering Innovations V, Inc. | Fusosome compositions for cns delivery |
| CN113631718A (zh) | 2018-11-14 | 2021-11-09 | 旗舰先锋创新V股份有限公司 | 用于特定隔室货物递送的组合物和方法 |
| CN110679548B (zh) * | 2019-10-24 | 2021-11-30 | 南方医科大学南方医院 | 一种自闭症小鼠模型的构建方法 |
| CN111759857A (zh) * | 2020-06-30 | 2020-10-13 | 宁波市微循环与莨菪类药研究所 | Gabrd甲基化靶点在制备抗海洛因复吸药物中的应用 |
| CN115480485B (zh) * | 2022-09-14 | 2024-09-10 | 南开大学 | 一种基于数据驱动模型的软镜扭转运动安全控制方法 |
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| CN119331917B (zh) * | 2024-10-28 | 2025-10-17 | 北京爱思益普生物科技股份有限公司 | 能够表达GlyR α1/β型GlyR的细胞株及其制备方法 |
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| US3644643A (en) * | 1969-10-13 | 1972-02-22 | Unimed Inc | Method of reducing intraocular pressure using glycine |
| US4559157A (en) | 1983-04-21 | 1985-12-17 | Creative Products Resource Associates, Ltd. | Cosmetic applicator useful for skin moisturizing |
| LU84979A1 (fr) | 1983-08-30 | 1985-04-24 | Oreal | Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux |
| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
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| US4992478A (en) | 1988-04-04 | 1991-02-12 | Warner-Lambert Company | Antiinflammatory skin moisturizing composition and method of preparing same |
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| US6156303A (en) | 1997-06-11 | 2000-12-05 | University Of Washington | Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom |
| US6464986B1 (en) * | 2000-04-14 | 2002-10-15 | Allegan Sales, Inc. | Method for treating pain by peripheral administration of a neurotoxin |
| ATE437948T1 (de) | 2000-06-20 | 2009-08-15 | Bionomics Ltd | Mutation, welche mit epilepsie assoziiert ist |
| CA2438386A1 (en) * | 2001-02-16 | 2002-08-29 | Bristol-Myers Squibb Company | Polynucleotides encoding a novel glycine receptor alpha subunit expressed in the gastrointestinal tract, hgra4, and splice variant thereof |
| US20040058313A1 (en) | 2002-04-24 | 2004-03-25 | Abreu Marcio Marc | Compositions, targets, methods and devices for the therapy of ocular and periocular disorders |
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| WO2008024998A2 (en) | 2006-08-24 | 2008-02-28 | Virovek, Inc. | Expression in insect cells of genes with overlapping open reading frames, methods and compositions therefor |
| WO2008143875A1 (en) * | 2007-05-14 | 2008-11-27 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Targeted delivery of glycine receptors to excitable cells |
| EP2058401A1 (en) * | 2007-10-05 | 2009-05-13 | Genethon | Widespread gene delivery to motor neurons using peripheral injection of AAV vectors |
| EP2283038A1 (en) | 2008-04-30 | 2011-02-16 | Dublin City University | Compositions and methods for expressing in-frame multimeric proteins |
| EP2344636B1 (en) * | 2008-10-09 | 2017-12-06 | Howard Hughes Medical Institute | Novel chimeric ligand-gated ion channels and methods of use thereof |
| US20130184318A1 (en) | 2010-04-30 | 2013-07-18 | The Regents Of The University Of California | Modulating compliance of trabecular meshwork |
| WO2012155091A1 (en) | 2011-05-11 | 2012-11-15 | Kirax Corporation | Package for improved treatment of conditions |
| AU2013293270B2 (en) | 2012-07-25 | 2018-08-16 | Massachusetts Institute Of Technology | Inducible DNA binding proteins and genome perturbation tools and applications thereof |
| EP2692868A1 (en) * | 2012-08-02 | 2014-02-05 | Universitat Autònoma De Barcelona | Adeno-associated viral (AAV) vectors useful for transducing adipose tissue |
| WO2014093251A1 (en) * | 2012-12-10 | 2014-06-19 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Engineered receptors and their use |
| AU2015204691A1 (en) | 2014-01-08 | 2016-07-21 | Circuit Therapeutics, Inc. | Method for therapeutic management of ocular hypertension |
| US20150283398A1 (en) | 2014-03-27 | 2015-10-08 | Circuit Therapeutics, Inc. | System and method for therapeutic management of cough |
| EP3204503A1 (en) | 2014-10-06 | 2017-08-16 | Arthrogen BV | Aav-based gene therapy |
| AU2016324317A1 (en) * | 2015-09-17 | 2018-03-08 | Coda Biotherapeutics, Inc. | Compositions and methods for treating neurological disorders |
| GB2547179A (en) | 2015-10-26 | 2017-08-16 | Quethera Ltd | Genetic construct |
| JP7496667B2 (ja) | 2016-04-21 | 2024-06-07 | ビロベク，インコーポレイテッド | 昆虫細胞中でのａａｖ生成、方法およびその組成物 |
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- 2016-09-28 EP EP16852497.3A patent/EP3355938B1/en active Active
- 2016-09-28 KR KR1020187012245A patent/KR20180072713A/ko not_active Ceased
- 2016-09-28 WO PCT/US2016/054199 patent/WO2017058926A1/en not_active Ceased
- 2016-09-28 HK HK18112264.4A patent/HK1252915A1/zh unknown
- 2016-09-28 BR BR112018006480A patent/BR112018006480A2/pt not_active IP Right Cessation
- 2016-09-28 CA CA2999279A patent/CA2999279A1/en not_active Abandoned
- 2016-09-28 CN CN201680068232.8A patent/CN108289965A/zh active Pending
- 2016-09-28 SG SG10201912703PA patent/SG10201912703PA/en unknown
- 2016-09-28 AU AU2016332847A patent/AU2016332847B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016332847B2 (en) | 2023-08-10 |
| US11407812B2 (en) | 2022-08-09 |
| AU2016332847A2 (en) | 2023-08-03 |
| WO2017058926A1 (en) | 2017-04-06 |
| JP7097070B2 (ja) | 2022-07-07 |
| EP3355938B1 (en) | 2024-02-07 |
| KR20180072713A (ko) | 2018-06-29 |
| CN108289965A (zh) | 2018-07-17 |
| BR112018006480A2 (pt) | 2018-10-09 |
| EP3355938A1 (en) | 2018-08-08 |
| CA2999279A1 (en) | 2017-04-06 |
| HK1252915A1 (zh) | 2019-06-06 |
| JP2018533976A (ja) | 2018-11-22 |
| US20190010210A1 (en) | 2019-01-10 |
| EP3355938A4 (en) | 2019-03-06 |
| AU2016332847A1 (en) | 2018-04-19 |
| SG10201912703PA (en) | 2020-02-27 |
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