KR20250007548A - 세포의 분화 상태를 분류하는 방법 및 관련 분화된 세포 조성물 - Google Patents

세포의 분화 상태를 분류하는 방법 및 관련 분화된 세포 조성물 Download PDF

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KR20250007548A
KR20250007548A KR1020247037398A KR20247037398A KR20250007548A KR 20250007548 A KR20250007548 A KR 20250007548A KR 1020247037398 A KR1020247037398 A KR 1020247037398A KR 20247037398 A KR20247037398 A KR 20247037398A KR 20250007548 A KR20250007548 A KR 20250007548A
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cells
genes
differentiation state
differentiation
cell
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Korean (ko)
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짐 모스먼
데렌 바켄
로이 윌리암스
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아스펜 뉴로사이언스 인코포레이티드
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    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin

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KR1020247037398A 2022-04-15 2023-04-14 세포의 분화 상태를 분류하는 방법 및 관련 분화된 세포 조성물 Pending KR20250007548A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263331783P 2022-04-15 2022-04-15
US63/331,783 2022-04-15
US202263353525P 2022-06-17 2022-06-17
US63/353,525 2022-06-17
PCT/US2023/065811 WO2023201361A1 (en) 2022-04-15 2023-04-14 Methods of classifying the differentiation state of cells and related compositions of differentiated cells

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KR20250007548A true KR20250007548A (ko) 2025-01-14

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US (1) US20230377685A1 (https=)
EP (1) EP4508645A1 (https=)
JP (1) JP2025512442A (https=)
KR (1) KR20250007548A (https=)
CN (1) CN119384700A (https=)
AU (1) AU2023254262A1 (https=)
CA (1) CA3250467A1 (https=)
IL (1) IL316055A (https=)
MX (1) MX2024012742A (https=)
WO (1) WO2023201361A1 (https=)

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JP2025512442A (ja) 2025-04-17
US20230377685A1 (en) 2023-11-23
IL316055A (en) 2024-11-01
AU2023254262A1 (en) 2024-10-17
CA3250467A1 (en) 2023-10-19
EP4508645A1 (en) 2025-02-19
MX2024012742A (es) 2025-04-02
CN119384700A (zh) 2025-01-28
WO2023201361A1 (en) 2023-10-19

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