KR20250007029A - FimH 돌연변이체, 이를 포함하는 조성물 및 이의 용도 - Google Patents
FimH 돌연변이체, 이를 포함하는 조성물 및 이의 용도 Download PDFInfo
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- KR20250007029A KR20250007029A KR1020247041946A KR20247041946A KR20250007029A KR 20250007029 A KR20250007029 A KR 20250007029A KR 1020247041946 A KR1020247041946 A KR 1020247041946A KR 20247041946 A KR20247041946 A KR 20247041946A KR 20250007029 A KR20250007029 A KR 20250007029A
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- South Korea
- Prior art keywords
- fimh
- polypeptide
- val
- thr
- gly
- Prior art date
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Classifications
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- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21151126.6 | 2021-01-12 | ||
| EP21151126 | 2021-01-12 | ||
| KR1020237026809A KR102746713B1 (ko) | 2021-01-12 | 2022-01-11 | FimH 돌연변이체, 이를 포함하는 조성물 및 이의 용도 |
| PCT/IB2022/050166 WO2022153166A1 (en) | 2021-01-12 | 2022-01-11 | Fimh mutants, compositions therewith and use thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237026809A Division KR102746713B1 (ko) | 2021-01-12 | 2022-01-11 | FimH 돌연변이체, 이를 포함하는 조성물 및 이의 용도 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20250007029A true KR20250007029A (ko) | 2025-01-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247041946A Pending KR20250007029A (ko) | 2021-01-12 | 2022-01-11 | FimH 돌연변이체, 이를 포함하는 조성물 및 이의 용도 |
| KR1020237026809A Active KR102746713B1 (ko) | 2021-01-12 | 2022-01-11 | FimH 돌연변이체, 이를 포함하는 조성물 및 이의 용도 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237026809A Active KR102746713B1 (ko) | 2021-01-12 | 2022-01-11 | FimH 돌연변이체, 이를 포함하는 조성물 및 이의 용도 |
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|---|---|
| US (3) | US11725028B2 (enExample) |
| EP (1) | EP4277921A1 (enExample) |
| JP (2) | JP7532672B2 (enExample) |
| KR (2) | KR20250007029A (enExample) |
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| AU (1) | AU2022207740B2 (enExample) |
| CA (1) | CA3207841A1 (enExample) |
| IL (1) | IL303954B2 (enExample) |
| MX (1) | MX2023008251A (enExample) |
| TW (1) | TW202241929A (enExample) |
| WO (1) | WO2022153166A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115038461A (zh) | 2020-01-16 | 2022-09-09 | 杨森制药公司 | FimH突变体、其组合物及其用途 |
| WO2022153166A1 (en) | 2021-01-12 | 2022-07-21 | Janssen Pharmaceuticals, Inc. | Fimh mutants, compositions therewith and use thereof |
| JP2025503423A (ja) * | 2021-12-17 | 2025-02-04 | ファイザー・インク | ポリヌクレオチド組成物およびその使用 |
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| US4866034A (en) | 1982-05-26 | 1989-09-12 | Ribi Immunochem Research Inc. | Refined detoxified endotoxin |
| US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
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| US4877611A (en) | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
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| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| CA2017507C (en) | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
| JPH0655749B2 (ja) | 1989-09-20 | 1994-07-27 | 日本たばこ産業株式会社 | リピッドａ単糖類縁体 |
| US5370872A (en) | 1991-08-12 | 1994-12-06 | Swiss Serum And Vaccine Institute Berne | Escherichia coliO-polysaccharide-protein conjugate vaccine |
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| EP0671948B1 (en) | 1992-06-25 | 1997-08-13 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Vaccine composition containing adjuvants |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| ATE278419T1 (de) | 1997-04-01 | 2004-10-15 | Corixa Corp | Wässerige immunologische adjuvantzusammensetzungen aus monophosphoryllipid a |
| US6491919B2 (en) | 1997-04-01 | 2002-12-10 | Corixa Corporation | Aqueous immunologic adjuvant compostions of monophosphoryl lipid A |
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| US6858211B1 (en) | 1998-07-20 | 2005-02-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccines against Escherichia coli O157 infection |
| DK1126876T3 (da) | 1998-10-16 | 2007-07-02 | Glaxosmithkline Biolog Sa | Adjuvanssystemer og vacciner |
| JP2003505030A (ja) * | 1999-07-15 | 2003-02-12 | メディミューン，インコーポレーテッド | ＦｉｍＨアドヘジンベイストワクチン |
| WO2001025254A2 (en) | 1999-10-04 | 2001-04-12 | University Of Maryland Biotechnology Institute | Novel adjuvant comprising a lipopolysaccharide antagonist |
| ATE398463T1 (de) | 2000-04-13 | 2008-07-15 | Corixa Corp | Immunostimulierende zusammnensetzungen die aminoalkyl glucosaminidephosphat und qs-21 enthalten |
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| CA2420234A1 (en) * | 2000-08-18 | 2002-02-28 | Medimmune, Inc. | Method of administering fimh protein as a vaccine for urinary tract infections |
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| CN115038461A (zh) | 2020-01-16 | 2022-09-09 | 杨森制药公司 | FimH突变体、其组合物及其用途 |
| WO2022153166A1 (en) | 2021-01-12 | 2022-07-21 | Janssen Pharmaceuticals, Inc. | Fimh mutants, compositions therewith and use thereof |
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| AR124604A1 (es) | 2023-04-12 |
| IL303954A (en) | 2023-08-01 |
| KR20230125842A (ko) | 2023-08-29 |
| US20250289854A1 (en) | 2025-09-18 |
| JP2024109576A (ja) | 2024-08-14 |
| WO2022153166A1 (en) | 2022-07-21 |
| US12297238B2 (en) | 2025-05-13 |
| IL303954B2 (en) | 2025-04-01 |
| EP4277921A1 (en) | 2023-11-22 |
| US20220220159A1 (en) | 2022-07-14 |
| AU2022207740B2 (en) | 2024-06-06 |
| US11725028B2 (en) | 2023-08-15 |
| KR102746713B1 (ko) | 2024-12-24 |
| CA3207841A1 (en) | 2022-07-21 |
| JP2024502854A (ja) | 2024-01-23 |
| MX2023008251A (es) | 2023-07-26 |
| US20230406890A1 (en) | 2023-12-21 |
| CN116888140A (zh) | 2023-10-13 |
| TW202241929A (zh) | 2022-11-01 |
| AU2022207740A9 (en) | 2024-09-05 |
| IL303954B1 (en) | 2024-12-01 |
| AU2022207740A1 (en) | 2023-06-29 |
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