KR20240142624A - 만능줄기세포에서 분화된 면역저하 베타세포 및 관련 용도 및 방법 - Google Patents

만능줄기세포에서 분화된 면역저하 베타세포 및 관련 용도 및 방법 Download PDF

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KR20240142624A
KR20240142624A KR1020247026729A KR20247026729A KR20240142624A KR 20240142624 A KR20240142624 A KR 20240142624A KR 1020247026729 A KR1020247026729 A KR 1020247026729A KR 20247026729 A KR20247026729 A KR 20247026729A KR 20240142624 A KR20240142624 A KR 20240142624A
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modified
cell
molecules
beta
equal
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소냐 슈레퍼
제프리 알. 밀먼
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사나 바이오테크놀로지, 인크.
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KR1020247026729A 2022-01-10 2023-01-09 만능줄기세포에서 분화된 면역저하 베타세포 및 관련 용도 및 방법 Pending KR20240142624A (ko)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202263298214P 2022-01-10 2022-01-10
US63/298,214 2022-01-10
US202263320691P 2022-03-16 2022-03-16
US63/320,691 2022-03-16
US202263322208P 2022-03-21 2022-03-21
US63/322,208 2022-03-21
US202263352605P 2022-06-15 2022-06-15
US63/352,605 2022-06-15
US202263353534P 2022-06-17 2022-06-17
US63/353,534 2022-06-17
PCT/US2023/060341 WO2023133568A2 (en) 2022-01-10 2023-01-09 Hypoimmune beta cells differentiated from pluripotent stem cells and related uses and methods

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KR20240142624A true KR20240142624A (ko) 2024-09-30

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KR1020247026729A Pending KR20240142624A (ko) 2022-01-10 2023-01-09 만능줄기세포에서 분화된 면역저하 베타세포 및 관련 용도 및 방법

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US (1) US20250223564A1 (https=)
EP (1) EP4463171A4 (https=)
JP (1) JP2025504392A (https=)
KR (1) KR20240142624A (https=)
AU (1) AU2023204829A1 (https=)
CA (1) CA3246902A1 (https=)
IL (1) IL314029A (https=)
MX (1) MX2024008571A (https=)
WO (1) WO2023133568A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024229302A1 (en) * 2023-05-03 2024-11-07 Sana Biotechnology, Inc. Methods of dosing and administration of engineered islet cells
IL325954A (en) * 2023-07-28 2026-03-01 Vertex Pharma Cell therapy for diabetes
CN116732099B (zh) * 2023-08-07 2023-11-24 北赛泓升(北京)生物科技有限公司 一种干细胞多重CRISPR/Cas基因组编辑方法
WO2025117331A1 (en) 2023-12-01 2025-06-05 Eli Lilly And Company Methods of making stem cell-derived islet-like cells, as well as populations and compositions including the same
WO2025212859A1 (en) * 2024-04-03 2025-10-09 Solid Biosciences, Inc. Methods and constructs for increasing solid organ transplant survival

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE057135T2 (hu) * 2015-09-01 2022-04-28 Ncardia B V In vitro módszer egy humán pluripotens õssejtpopuláció kardiomiocita sejtpopulációvá történõ differenciálására
CN110177869A (zh) * 2017-01-13 2019-08-27 加利福尼亚大学董事会 免疫改造的多能细胞
US20210308183A1 (en) * 2018-07-17 2021-10-07 The Regents Of The University Of California Chimeric antigen receptor t cells derived from immunoengineered pluripotent stem cells
BR112021000637A2 (pt) * 2018-07-17 2021-04-13 The Regents Of The University Of California Célula cardíaca hipoimune isolada, método para tratar um paciente que sofre de uma afecção ou doença cardíaca, método para produzir uma população de células cardíacas hipoimunes, célula endotelial hipoimune isolada, método para tratar um paciente que sofre de uma afecção ou doença vascular, método para produzir uma população de células endoteliais hipoimunes, neurônio dopaminérgico hipoimune isolado, método para tratar um paciente que sofre de uma doença ou afecção neurodegenerativa, método para produzir uma população de neurônios dopaminérgicos hipoimunes, célula de ilhota pancreática hipoimune isolada, método para tratar um paciente que sofre de diabetes, método para produzir uma população de células de ilhota pancreática hipoimunes, célula de epitélio pigmentado da retina (rpe) hipoimune isolada, método para tratar um paciente que sofre de uma afecção ocular, e método para produzir uma população de células de epitélio pigmentado da retina (rpe) hipoimunes
CN115916962A (zh) * 2020-04-27 2023-04-04 萨那生物技术股份有限公司 低免疫原性细胞的重复给药

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EP4463171A2 (en) 2024-11-20
WO2023133568A2 (en) 2023-07-13
CA3246902A1 (en) 2023-07-13
EP4463171A4 (en) 2026-03-18
US20250223564A1 (en) 2025-07-10
WO2023133568A3 (en) 2023-08-10
MX2024008571A (es) 2024-09-19
JP2025504392A (ja) 2025-02-12
IL314029A (en) 2024-08-01
AU2023204829A1 (en) 2024-07-11

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