KR20240021734A - 근시의 치료 - Google Patents
근시의 치료 Download PDFInfo
- Publication number
- KR20240021734A KR20240021734A KR1020237030954A KR20237030954A KR20240021734A KR 20240021734 A KR20240021734 A KR 20240021734A KR 1020237030954 A KR1020237030954 A KR 1020237030954A KR 20237030954 A KR20237030954 A KR 20237030954A KR 20240021734 A KR20240021734 A KR 20240021734A
- Authority
- KR
- South Korea
- Prior art keywords
- composition
- copper
- administered
- myopia
- containing agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000004379 myopia Effects 0.000 title claims abstract description 46
- 208000001491 myopia Diseases 0.000 title claims abstract description 46
- 239000000203 mixture Substances 0.000 claims abstract description 136
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract description 92
- 229910052802 copper Inorganic materials 0.000 claims abstract description 91
- 239000010949 copper Substances 0.000 claims abstract description 91
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 73
- 238000000034 method Methods 0.000 claims abstract description 47
- YRNNKGFMTBWUGL-UHFFFAOYSA-L copper(ii) perchlorate Chemical compound [Cu+2].[O-]Cl(=O)(=O)=O.[O-]Cl(=O)(=O)=O YRNNKGFMTBWUGL-UHFFFAOYSA-L 0.000 claims description 32
- -1 pH adjusters Substances 0.000 claims description 18
- 239000003889 eye drop Substances 0.000 claims description 11
- 229920000642 polymer Polymers 0.000 claims description 8
- 239000002904 solvent Substances 0.000 claims description 8
- 230000004515 progressive myopia Effects 0.000 claims description 7
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 6
- 239000004480 active ingredient Substances 0.000 claims description 5
- 239000000499 gel Substances 0.000 claims description 5
- 239000003755 preservative agent Substances 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 208000001309 degenerative myopia Diseases 0.000 claims description 4
- 230000002459 sustained effect Effects 0.000 claims description 4
- 239000002562 thickening agent Substances 0.000 claims description 4
- HXUMOVKKXUVBRH-UHFFFAOYSA-L copper diperbromate Chemical compound Br(=O)(=O)(=O)[O-].[Cu+2].Br(=O)(=O)(=O)[O-] HXUMOVKKXUVBRH-UHFFFAOYSA-L 0.000 claims description 3
- KAGCXMYEBHGUDI-UHFFFAOYSA-L copper;diperiodate Chemical compound [Cu+2].[O-]I(=O)(=O)=O.[O-]I(=O)(=O)=O KAGCXMYEBHGUDI-UHFFFAOYSA-L 0.000 claims description 3
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- 150000001875 compounds Chemical class 0.000 description 35
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- 239000013543 active substance Substances 0.000 description 11
- 108010057846 lysinenorleucine Proteins 0.000 description 11
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
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- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- NHELIHXBJRANPL-UHFFFAOYSA-L copper;diperchlorate;hexahydrate Chemical compound O.O.O.O.O.O.[Cu+2].[O-]Cl(=O)(=O)=O.[O-]Cl(=O)(=O)=O NHELIHXBJRANPL-UHFFFAOYSA-L 0.000 description 6
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- 239000000126 substance Substances 0.000 description 5
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- 201000004569 Blindness Diseases 0.000 description 4
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- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 4
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- 238000012552 review Methods 0.000 description 1
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- 229940081623 rose bengal Drugs 0.000 description 1
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- 235000005713 safflower oil Nutrition 0.000 description 1
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- IRPLSAGFWHCJIQ-UHFFFAOYSA-N selanylidenecopper Chemical compound [Se]=[Cu] IRPLSAGFWHCJIQ-UHFFFAOYSA-N 0.000 description 1
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- 239000004332 silver Substances 0.000 description 1
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- WBHQBSYUUJJSRZ-UHFFFAOYSA-M sodium bisulfate Chemical compound [Na+].OS([O-])(=O)=O WBHQBSYUUJJSRZ-UHFFFAOYSA-M 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163148344P | 2021-02-11 | 2021-02-11 | |
| US63/148,344 | 2021-02-11 | ||
| PCT/US2022/016205 WO2022174094A1 (en) | 2021-02-11 | 2022-02-11 | Treatment of myopia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20240021734A true KR20240021734A (ko) | 2024-02-19 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237030954A Pending KR20240021734A (ko) | 2021-02-11 | 2022-02-11 | 근시의 치료 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240122974A1 (https=) |
| EP (1) | EP4291163A4 (https=) |
| JP (1) | JP2024508706A (https=) |
| KR (1) | KR20240021734A (https=) |
| CN (1) | CN118234482A (https=) |
| AU (1) | AU2022220331A1 (https=) |
| CA (1) | CA3208185A1 (https=) |
| TW (1) | TW202302121A (https=) |
| WO (1) | WO2022174094A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250109788A (ko) * | 2018-01-05 | 2025-07-17 | 유니버시티 오브 유타 리서치 파운데이션 | 근시 진행의 치료 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040058015A1 (en) * | 2000-06-01 | 2004-03-25 | Yuanjin Tao | Compositions and methods for treating eye discomfort and eye disease |
| US20040001791A1 (en) * | 2000-11-16 | 2004-01-01 | Zeiler Kenneth T. | Composition, method of use, and devices for the treatment of onychomycosis |
| US9504603B2 (en) * | 2012-04-02 | 2016-11-29 | Ocuject, Llc | Intraocular delivery devices and methods therefor |
| JP6898734B2 (ja) * | 2013-10-07 | 2021-07-07 | オクジェクト, リミテッド ライアビリティー カンパニーOcuject, Llc | 針アセンブリ |
| US11065275B2 (en) * | 2016-03-08 | 2021-07-20 | University Of Utah Research Foundation | Cross-linking agents and associated methods |
| KR20250109788A (ko) * | 2018-01-05 | 2025-07-17 | 유니버시티 오브 유타 리서치 파운데이션 | 근시 진행의 치료 |
| CN109776623B (zh) * | 2019-03-05 | 2021-05-07 | 潍坊科技学院 | 一种含氟草酰胺同/异核化合物的制备方法与应用 |
-
2022
- 2022-02-10 TW TW111104966A patent/TW202302121A/zh unknown
- 2022-02-11 AU AU2022220331A patent/AU2022220331A1/en active Pending
- 2022-02-11 CN CN202280027799.6A patent/CN118234482A/zh active Pending
- 2022-02-11 WO PCT/US2022/016205 patent/WO2022174094A1/en not_active Ceased
- 2022-02-11 CA CA3208185A patent/CA3208185A1/en active Pending
- 2022-02-11 JP JP2023548552A patent/JP2024508706A/ja active Pending
- 2022-02-11 KR KR1020237030954A patent/KR20240021734A/ko active Pending
- 2022-02-11 US US18/546,258 patent/US20240122974A1/en active Pending
- 2022-02-11 EP EP22753451.8A patent/EP4291163A4/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3208185A1 (en) | 2022-08-18 |
| TW202302121A (zh) | 2023-01-16 |
| CN118234482A (zh) | 2024-06-21 |
| US20240122974A1 (en) | 2024-04-18 |
| JP2024508706A (ja) | 2024-02-28 |
| AU2022220331A1 (en) | 2023-09-28 |
| WO2022174094A1 (en) | 2022-08-18 |
| EP4291163A1 (en) | 2023-12-20 |
| EP4291163A4 (en) | 2025-01-01 |
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| PA0105 | International application |
Patent event date: 20230911 Patent event code: PA01051R01D Comment text: International Patent Application |
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| PA0201 | Request for examination |
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