KR20240019111A - Cd47 저해 물질, 면역 체크포인트 저해 물질 및 표준 요법의 병용에 의한 암 치료법 - Google Patents
Cd47 저해 물질, 면역 체크포인트 저해 물질 및 표준 요법의 병용에 의한 암 치료법 Download PDFInfo
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- A—HUMAN NECESSITIES
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPJP-P-2021-097024 | 2021-06-10 | ||
| JP2021097027 | 2021-06-10 | ||
| JP2021097024 | 2021-06-10 | ||
| JPJP-P-2021-097027 | 2021-06-10 | ||
| PCT/JP2022/023300 WO2022260132A1 (ja) | 2021-06-10 | 2022-06-09 | Cd47阻害物質、免疫チェックポイント阻害物質および標準療法の併用によるがん治療法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20240019111A true KR20240019111A (ko) | 2024-02-14 |
Family
ID=84424587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237041872A Pending KR20240019111A (ko) | 2021-06-10 | 2022-06-09 | Cd47 저해 물질, 면역 체크포인트 저해 물질 및 표준 요법의 병용에 의한 암 치료법 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240254226A1 (https=) |
| EP (1) | EP4353265A4 (https=) |
| JP (2) | JP7556468B2 (https=) |
| KR (1) | KR20240019111A (https=) |
| AU (1) | AU2022289317A1 (https=) |
| CA (1) | CA3222362A1 (https=) |
| TW (1) | TW202317183A (https=) |
| WO (1) | WO2022260132A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI876305B (zh) * | 2022-04-05 | 2025-03-11 | 美商基利科學股份有限公司 | 用於治療結腸直腸癌之組合療法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009091601A1 (en) | 2008-01-15 | 2009-07-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for manipulating phagocytosis mediated by cd47 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL148079A0 (en) | 1999-08-24 | 2002-09-12 | Medarex Inc | Human ctla-4 antibodies and compositions containing the same |
| RU2494107C2 (ru) | 2005-05-09 | 2013-09-27 | Оно Фармасьютикал Ко., Лтд. | Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами |
| CN104356236B (zh) | 2005-07-01 | 2020-07-03 | E.R.施贵宝&圣斯有限责任公司 | 抗程序性死亡配体1(pd-l1)的人单克隆抗体 |
| HRP20131167T1 (hr) | 2007-06-18 | 2014-01-03 | Merck Sharp & Dohme B.V. | Antitijela za humani receptor programirane smrti pd-1 |
| HRP20221260T1 (hr) | 2010-05-14 | 2023-03-03 | The Board Of Trustees Of The Leland Stanford Junior University | Humanizirana i kimerna monoklonska protutijela za cd47 |
| WO2013181452A1 (en) * | 2012-05-31 | 2013-12-05 | Genentech, Inc. | Methods of treating cancer using pd-l1 axis binding antagonists and vegf antagonists |
| SI4177270T1 (sl) * | 2017-10-18 | 2024-10-30 | Forty Seven, Inc. | Terapija za raka jajčnikov na osnovi sredstva proti cd47 |
| CN111479575B (zh) * | 2017-12-13 | 2024-03-22 | 北卡罗莱纳州立大学 | 包含化疗剂和检查点抑制剂的组合物及使用方法 |
| JP7491220B2 (ja) * | 2018-11-27 | 2024-05-28 | 小野薬品工業株式会社 | 免疫チェックポイント阻害薬およびfolfirinox療法との併用によるがん治療 |
| US20220211847A1 (en) * | 2019-05-06 | 2022-07-07 | Medimmune Limited | Combination of monalizumab, durvalumab, chemotherapy and bevacizumab or cetuximab for the treatment of colorectal cancer |
| KR20220091576A (ko) * | 2019-10-31 | 2022-06-30 | 포티 세븐, 인코포레이티드 | 혈액암의 항-cd47 및 항-cd20 기반 치료 |
| TWI876305B (zh) * | 2022-04-05 | 2025-03-11 | 美商基利科學股份有限公司 | 用於治療結腸直腸癌之組合療法 |
-
2022
- 2022-06-09 US US18/566,424 patent/US20240254226A1/en active Pending
- 2022-06-09 EP EP22820311.3A patent/EP4353265A4/en active Pending
- 2022-06-09 AU AU2022289317A patent/AU2022289317A1/en active Pending
- 2022-06-09 TW TW111121390A patent/TW202317183A/zh unknown
- 2022-06-09 JP JP2023527921A patent/JP7556468B2/ja active Active
- 2022-06-09 CA CA3222362A patent/CA3222362A1/en active Pending
- 2022-06-09 WO PCT/JP2022/023300 patent/WO2022260132A1/ja not_active Ceased
- 2022-06-09 KR KR1020237041872A patent/KR20240019111A/ko active Pending
-
2024
- 2024-09-11 JP JP2024157591A patent/JP2024174997A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009091601A1 (en) | 2008-01-15 | 2009-07-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for manipulating phagocytosis mediated by cd47 |
Non-Patent Citations (4)
| Title |
|---|
| 비특허문헌 1: 트렌즈·인·셀·바이올로지(Trends in Cell Biology), 제11권(3), 130-135 페이지, 2001년 |
| 비특허문헌 2: 저널·오브·익스페리멘탈·메디신(Journal of Experimental Medicine), 제194권(4), 541-549 페이지, 2001년 |
| 비특허문헌 3: 저널·오브·이뮤놀로지(Journal of Immunology), 제174권(4), 2004-2011 페이지, 2005년 |
| 비특허문헌 4: 셀(Cell), 제138권(2), 286-299 페이지, 2009년 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022260132A1 (ja) | 2022-12-15 |
| JPWO2022260132A1 (https=) | 2022-12-15 |
| EP4353265A4 (en) | 2024-10-02 |
| US20240254226A1 (en) | 2024-08-01 |
| EP4353265A1 (en) | 2024-04-17 |
| JP2024174997A (ja) | 2024-12-17 |
| AU2022289317A1 (en) | 2023-12-14 |
| JP7556468B2 (ja) | 2024-09-26 |
| CA3222362A1 (en) | 2022-12-15 |
| TW202317183A (zh) | 2023-05-01 |
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