KR20230127266A - 서방형 우파다시티닙 제형 - Google Patents
서방형 우파다시티닙 제형 Download PDFInfo
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- KR20230127266A KR20230127266A KR1020237025347A KR20237025347A KR20230127266A KR 20230127266 A KR20230127266 A KR 20230127266A KR 1020237025347 A KR1020237025347 A KR 1020237025347A KR 20237025347 A KR20237025347 A KR 20237025347A KR 20230127266 A KR20230127266 A KR 20230127266A
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- dosage form
- solid dosage
- upadacitinib
- sustained release
- release
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A—HUMAN NECESSITIES
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
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- A—HUMAN NECESSITIES
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- A61K9/2833—Organic macromolecular compounds
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- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
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- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063131564P | 2020-12-29 | 2020-12-29 | |
| US63/131,564 | 2020-12-29 | ||
| PCT/US2021/065443 WO2022147073A1 (en) | 2020-12-29 | 2021-12-29 | Extended release upadacitinib formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20230127266A true KR20230127266A (ko) | 2023-08-31 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020237025347A Pending KR20230127266A (ko) | 2020-12-29 | 2021-12-29 | 서방형 우파다시티닙 제형 |
Country Status (8)
| Country | Link |
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| US (3) | US20240316040A1 (https=) |
| EP (1) | EP4271380A4 (https=) |
| JP (1) | JP2024501051A (https=) |
| KR (1) | KR20230127266A (https=) |
| AU (1) | AU2021411506A1 (https=) |
| CA (1) | CA3206839A1 (https=) |
| MX (1) | MX2023007741A (https=) |
| WO (1) | WO2022147073A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111909160B (zh) * | 2019-05-09 | 2024-05-28 | 苏州鹏旭医药科技有限公司 | 一种乌帕替尼盐类化合物及其制备方法 |
| CA3248817A1 (en) * | 2022-01-20 | 2023-07-27 | Renata Pharmaceutical (Ireland) Limited | Extended-release pharmaceutical composition of Upadacitinib |
| EP4583877A1 (en) * | 2022-09-09 | 2025-07-16 | Intas Pharmaceuticals Ltd. | Upadacitinib formulation |
| CN117357492A (zh) * | 2023-10-31 | 2024-01-09 | 苏州天马医药集团天吉生物制药有限公司 | 一种乌帕替尼缓释片剂及其制备方法 |
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| MXPA06003453A (es) * | 2003-09-26 | 2006-08-31 | Johnson & Johnson | Barra de empuje oros para el suministro controlado de agentes activos. |
| US20090099154A1 (en) * | 2005-06-29 | 2009-04-16 | Panacea Biotec Ltd. | Pharmaceutical Sustained Release Compositions and Processes Thereof |
| JP5052051B2 (ja) * | 2006-06-16 | 2012-10-17 | トーアエイヨー株式会社 | 腸溶性顆粒剤及びその製造方法 |
| US20140271892A1 (en) * | 2013-03-15 | 2014-09-18 | Mcneil-Ppc, Inc. | Phenylephrine resinate particles having good auc |
| AU2018230500B2 (en) * | 2017-03-09 | 2024-03-07 | Abbvie Inc. | Methods of treating Crohn's disease and ulcerative colitis |
| AU2018312349A1 (en) * | 2017-08-01 | 2020-02-06 | Theravance Biopharma R&D Ip, Llc | Pyrazolo and triazolo bicyclic compounds as JAK kinase inhibitors |
| WO2020115212A1 (en) * | 2018-12-05 | 2020-06-11 | Lek Pharmaceuticals D.D. | Crystalline phosphate salt of selective jak1 inhibitor upadacitinib |
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2021
- 2021-12-29 EP EP21916388.8A patent/EP4271380A4/en active Pending
- 2021-12-29 KR KR1020237025347A patent/KR20230127266A/ko active Pending
- 2021-12-29 JP JP2023539796A patent/JP2024501051A/ja active Pending
- 2021-12-29 MX MX2023007741A patent/MX2023007741A/es unknown
- 2021-12-29 CA CA3206839A patent/CA3206839A1/en active Pending
- 2021-12-29 US US18/259,744 patent/US20240316040A1/en active Pending
- 2021-12-29 AU AU2021411506A patent/AU2021411506A1/en active Pending
- 2021-12-29 WO PCT/US2021/065443 patent/WO2022147073A1/en not_active Ceased
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2025
- 2025-01-17 US US19/027,247 patent/US20250161302A1/en not_active Abandoned
- 2025-09-09 US US19/323,495 patent/US20260007661A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022147073A1 (en) | 2022-07-07 |
| JP2024501051A (ja) | 2024-01-10 |
| AU2021411506A9 (en) | 2024-09-26 |
| MX2023007741A (es) | 2023-09-15 |
| US20240316040A1 (en) | 2024-09-26 |
| US20250161302A1 (en) | 2025-05-22 |
| CA3206839A1 (en) | 2022-07-07 |
| EP4271380A4 (en) | 2025-01-22 |
| US20260007661A1 (en) | 2026-01-08 |
| AU2021411506A1 (en) | 2023-07-13 |
| EP4271380A1 (en) | 2023-11-08 |
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