KR20230113420A - 아실 설폰아미드의 다형체 - Google Patents

아실 설폰아미드의 다형체 Download PDF

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Publication number
KR20230113420A
KR20230113420A KR1020237025164A KR20237025164A KR20230113420A KR 20230113420 A KR20230113420 A KR 20230113420A KR 1020237025164 A KR1020237025164 A KR 1020237025164A KR 20237025164 A KR20237025164 A KR 20237025164A KR 20230113420 A KR20230113420 A KR 20230113420A
Authority
KR
South Korea
Prior art keywords
compound
formula
crystalline form
polymorphic crystalline
ray powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020237025164A
Other languages
English (en)
Korean (ko)
Inventor
제임스 프렌티스 데비드슨
마이클 마틴
페이 팡
마가렛 웡
Original Assignee
에프. 호프만-라 로슈 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 에프. 호프만-라 로슈 아게 filed Critical 에프. 호프만-라 로슈 아게
Publication of KR20230113420A publication Critical patent/KR20230113420A/ko
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020237025164A 2008-09-09 2009-08-31 아실 설폰아미드의 다형체 Ceased KR20230113420A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9536408P 2008-09-09 2008-09-09
US61/095,364 2008-09-09
KR1020227029185A KR102560207B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
PCT/EP2009/061185 WO2010028968A2 (en) 2008-09-09 2009-08-31 Polymorphs of acyl sulfonamides

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020227029185A Division KR102560207B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Publications (1)

Publication Number Publication Date
KR20230113420A true KR20230113420A (ko) 2023-07-28

Family

ID=41664548

Family Applications (7)

Application Number Title Priority Date Filing Date
KR1020237025164A Ceased KR20230113420A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020117005435A Active KR101678700B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020167020205A Active KR101822319B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020177036902A Ceased KR20180001582A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020187028288A Ceased KR20180110237A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020217027200A Active KR102437499B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020227029185A Active KR102560207B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Family Applications After (6)

Application Number Title Priority Date Filing Date
KR1020117005435A Active KR101678700B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020167020205A Active KR101822319B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020177036902A Ceased KR20180001582A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020187028288A Ceased KR20180110237A (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020217027200A Active KR102437499B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체
KR1020227029185A Active KR102560207B1 (ko) 2008-09-09 2009-08-31 아실 설폰아미드의 다형체

Country Status (16)

Country Link
US (1) US8063103B2 (cg-RX-API-DMAC7.html)
EP (1) EP2334638B1 (cg-RX-API-DMAC7.html)
JP (6) JP5989339B2 (cg-RX-API-DMAC7.html)
KR (7) KR20230113420A (cg-RX-API-DMAC7.html)
CN (1) CN102143943B (cg-RX-API-DMAC7.html)
AU (1) AU2009290988B2 (cg-RX-API-DMAC7.html)
BR (3) BR122021020475B1 (cg-RX-API-DMAC7.html)
CA (5) CA2735192C (cg-RX-API-DMAC7.html)
EA (1) EA019340B1 (cg-RX-API-DMAC7.html)
ES (1) ES2706875T3 (cg-RX-API-DMAC7.html)
IL (4) IL299322B2 (cg-RX-API-DMAC7.html)
MX (1) MX2011002319A (cg-RX-API-DMAC7.html)
PL (1) PL2334638T3 (cg-RX-API-DMAC7.html)
TR (1) TR201818979T4 (cg-RX-API-DMAC7.html)
UA (1) UA107561C2 (cg-RX-API-DMAC7.html)
WO (1) WO2010028968A2 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2644156C1 (ru) 2017-02-28 2018-02-08 Александр Васильевич Иващенко Пролекарство ингибитора NS5B HCV полимеразы, способ его получения и применения
RU2665383C9 (ru) * 2017-06-22 2019-07-23 Общество с ограниченной ответственностью "Вириом" Фармацевтическая наносуспензия для терапии ВИЧ-инфекции
RU2662160C9 (ru) * 2017-07-03 2018-10-22 Александрович Иващенко Андрей Комбинированный лекарственный препарат для терапии вирусных инфекций
RU2716257C1 (ru) * 2019-04-30 2020-03-11 Андрей Александрович Иващенко Активный компонент, фармацевтическая композиция и лекарственный препарат для терапии ВИЧ и СПИДа
RU2717101C1 (ru) 2019-06-03 2020-03-18 Андрей Александрович Иващенко Анелированные 9-гидрокси-1,8-диоксо-1,3,4,8-тетрагидро-2Н-пиридо[1,2-a]пиразин-7-карбоксамиды - ингибиторы интегразы ВИЧ, способы их получения и применения

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100519870B1 (ko) * 1997-01-23 2005-10-12 아스텔라스세이야쿠 가부시키가이샤 신규한 아미드 유도체 및 이를 함유하는 약제학적 조성물
US7166738B2 (en) * 2004-04-23 2007-01-23 Roche Palo Alto Llc Non-nucleoside reverse transcriptase inhibitors
US7625949B2 (en) 2004-04-23 2009-12-01 Roche Palo Alto Llc Methods for treating retroviral infections
AU2005235692B2 (en) * 2004-04-23 2011-11-10 F. Hoffmann-La Roche Ag Non-nucleoside reverse transcriptase inhibitors
US7618981B2 (en) * 2004-05-06 2009-11-17 Cytokinetics, Inc. Imidazopyridinyl-benzamide anti-cancer agents
EP1879567A1 (en) * 2005-04-28 2008-01-23 Pfizer Limited Amino acid derivatives
EP1940781A1 (en) * 2005-10-19 2008-07-09 F.Hoffmann-La Roche Ag Phenyl-acetamide nnrt inhibitors
CN103479604B (zh) * 2007-07-30 2016-08-10 阿迪生物科学公司 作为mek抑制剂的包括多晶型物的n-(芳氨基)磺酰胺衍生物和组合物、其使用方法和制备方法
CA2716082A1 (en) * 2008-03-04 2009-02-23 F. Hoffmann-La Roche Ag Process for preparing concentrated aqueous micellar solutions

Also Published As

Publication number Publication date
JP6450340B2 (ja) 2019-01-09
BRPI0918526B1 (pt) 2022-02-15
EP2334638A2 (en) 2011-06-22
CN102143943A (zh) 2011-08-03
KR102560207B1 (ko) 2023-07-27
KR101678700B1 (ko) 2016-11-22
JP2021176894A (ja) 2021-11-11
IL244350A0 (en) 2016-05-01
CA3059552C (en) 2021-03-16
JP2019194229A (ja) 2019-11-07
CA3003213C (en) 2021-07-20
EP2334638B1 (en) 2018-11-21
KR20210108499A (ko) 2021-09-02
AU2009290988B2 (en) 2016-01-28
JP2023082131A (ja) 2023-06-13
IL211353A0 (en) 2011-05-31
KR20220120723A (ko) 2022-08-30
JP2018058862A (ja) 2018-04-12
IL264118A (en) 2019-02-28
WO2010028968A2 (en) 2010-03-18
CA2949912C (en) 2019-12-03
KR102437499B1 (ko) 2022-08-29
IL299322A (en) 2023-02-01
BR122021020475B1 (pt) 2022-06-07
JP2016172741A (ja) 2016-09-29
JP2012502075A (ja) 2012-01-26
WO2010028968A3 (en) 2010-06-10
CN102143943B (zh) 2014-03-12
JP5989339B2 (ja) 2016-09-07
AU2009290988A1 (en) 2010-03-18
IL211353A (en) 2016-04-21
CA2735192A1 (en) 2010-03-18
TR201818979T4 (tr) 2019-01-21
KR20160092049A (ko) 2016-08-03
PL2334638T3 (pl) 2019-04-30
CA3059552A1 (en) 2010-03-18
CA2735192C (en) 2017-02-28
KR101822319B1 (ko) 2018-01-25
US8063103B2 (en) 2011-11-22
BR122021020474B1 (pt) 2022-06-07
CA2949912A1 (en) 2010-03-18
ES2706875T3 (es) 2019-04-01
IL299322B2 (en) 2024-10-01
MX2011002319A (es) 2011-04-05
UA107561C2 (xx) 2015-01-26
US20100063154A1 (en) 2010-03-11
KR20180110237A (ko) 2018-10-08
KR20180001582A (ko) 2018-01-04
EA201100451A1 (ru) 2011-10-31
KR20110053234A (ko) 2011-05-19
CA3086566A1 (en) 2010-03-18
IL299322B1 (en) 2024-06-01
BRPI0918526A2 (pt) 2015-12-01
CA3086566C (en) 2025-09-02
EA019340B1 (ru) 2014-02-28
CA3003213A1 (en) 2010-03-18

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Legal Events

Date Code Title Description
A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20230721

Application number text: 1020227029185

Filing date: 20220823

PG1501 Laying open of application
E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20240422

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20240829

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D