KR20230084337A - 인슐린 저항성에 대한 개선된 펩티드 약제 - Google Patents
인슐린 저항성에 대한 개선된 펩티드 약제 Download PDFInfo
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- KR20230084337A KR20230084337A KR1020237018945A KR20237018945A KR20230084337A KR 20230084337 A KR20230084337 A KR 20230084337A KR 1020237018945 A KR1020237018945 A KR 1020237018945A KR 20237018945 A KR20237018945 A KR 20237018945A KR 20230084337 A KR20230084337 A KR 20230084337A
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Immunology (AREA)
- Emergency Medicine (AREA)
- Toxicology (AREA)
- Child & Adolescent Psychology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
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| KR1020247042894A KR20250007694A (ko) | 2014-05-28 | 2015-05-28 | 인슐린 저항성에 대한 개선된 펩티드 약제 |
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| US62/004,156 | 2014-05-28 | ||
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Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2710031B9 (en) | 2011-05-18 | 2018-02-28 | Mederis Diabetes, LLC | Improved peptide pharmaceuticals for insulin resistance |
| JP6148228B2 (ja) * | 2011-05-18 | 2017-06-14 | ユーメデリス ファーマシューティカルズ，インク． | 改善されたペプチド製剤 |
| WO2014081872A1 (en) | 2012-11-20 | 2014-05-30 | Mederis Diabetes, Llc | Improved peptide pharmaceuticals for insulin resistance |
| WO2014081864A1 (en) * | 2012-11-20 | 2014-05-30 | Eumederis Pharmaceuticals, Inc. | Improved peptide pharmaceuticals |
| DK3155017T3 (da) | 2014-05-28 | 2024-04-15 | Mederis Diabetes Llc | Forbedrede lægemidler til insulinresistens |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| AU2018302022A1 (en) | 2017-07-17 | 2020-02-27 | Macregen, Inc. | Topical delivery of therapeutic agents comprising cell-penetrating peptides for use for the treatment of age-related macular degeneration and other eye diseases |
| CN111818971A (zh) | 2018-01-03 | 2020-10-23 | 梅德瑞斯糖尿病有限责任公司 | 用于治疗nash和其他紊乱的改进的肽药物 |
| KR20220143923A (ko) * | 2020-02-21 | 2022-10-25 | 스핏파이어 파마, 엘엘씨 | Glp-1r 및 gcgr 효능제, 제형 및 사용 방법 |
| US12171806B2 (en) | 2021-09-28 | 2024-12-24 | Spitfire Pharma Llc | Therapeutic regimens and methods for lowering blood glucose and/or body weight using GLP-1R and GCGR balanced agonists |
| KR20230129425A (ko) * | 2020-12-07 | 2023-09-08 | 스핏파이어 파마, 엘엘씨 | Glp-1r 및 gcgr의 균형 잡힌 작용제를 사용하여 혈당및/또는 체중을 낮추기 위한 치료 요법 및 방법 |
| CN113461747B (zh) * | 2021-07-12 | 2023-02-03 | 吉林化工学院 | 刺玫果中2个具有降血糖活性的化合物 |
| AU2024277652A1 (en) * | 2023-05-24 | 2025-12-11 | The United Bio-Technology (Hengqin) Co., Ltd. | Insulin derivative and use thereof |
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| KR101453037B1 (ko) | 2011-03-23 | 2014-10-21 | 주식회사 엘지화학 | 전극조립체 및 이의 제조방법 |
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| EP2710031B9 (en) * | 2011-05-18 | 2018-02-28 | Mederis Diabetes, LLC | Improved peptide pharmaceuticals for insulin resistance |
| WO2014081872A1 (en) | 2012-11-20 | 2014-05-30 | Mederis Diabetes, Llc | Improved peptide pharmaceuticals for insulin resistance |
| WO2014081864A1 (en) * | 2012-11-20 | 2014-05-30 | Eumederis Pharmaceuticals, Inc. | Improved peptide pharmaceuticals |
| PL2986313T3 (pl) * | 2013-04-18 | 2019-12-31 | Novo Nordisk A/S | Stabilni, dłużej działający współagoniści receptora glp-1/glukagonu do zastosowań medycznych |
| DK3155017T3 (da) | 2014-05-28 | 2024-04-15 | Mederis Diabetes Llc | Forbedrede lægemidler til insulinresistens |
| MD20170055A2 (ro) * | 2014-10-24 | 2017-09-30 | Merck Sharp & Dohme Corp | Co-agonişti ai receptorilor glucagonului şi GLP-1 |
| CN111818971A (zh) * | 2018-01-03 | 2020-10-23 | 梅德瑞斯糖尿病有限责任公司 | 用于治疗nash和其他紊乱的改进的肽药物 |
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2015
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- 2015-05-28 PL PL15798956.7T patent/PL3155017T4/pl unknown
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2016
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2022
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