KR20230084180A - 베타 코로나바이러스 저온순화 주 및 백신 - Google Patents
베타 코로나바이러스 저온순화 주 및 백신 Download PDFInfo
- Publication number
- KR20230084180A KR20230084180A KR1020237012671A KR20237012671A KR20230084180A KR 20230084180 A KR20230084180 A KR 20230084180A KR 1020237012671 A KR1020237012671 A KR 1020237012671A KR 20237012671 A KR20237012671 A KR 20237012671A KR 20230084180 A KR20230084180 A KR 20230084180A
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- South Korea
- Prior art keywords
- mutation
- amino acid
- seq
- leu
- acid sequence
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- C—CHEMISTRY; METALLURGY
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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- C12Y201/00—Transferases transferring one-carbon groups (2.1)
- C12Y201/01—Methyltransferases (2.1.1)
- C12Y201/01056—Methyltransferases (2.1.1) mRNA (guanine-N7-)-methyltransferase (2.1.1.56)
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- C12Y201/01—Methyltransferases (2.1.1)
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- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
- C12Y301/03084—ADP-ribose 1''-phosphate phosphatase (3.1.3.84)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
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- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPJP-P-2020-173494 | 2020-10-14 | ||
| JP2020173494 | 2020-10-14 | ||
| JPJP-P-2020-180524 | 2020-10-28 | ||
| JP2020180524 | 2020-10-28 | ||
| JP2020210564 | 2020-12-18 | ||
| JPJP-P-2020-210564 | 2020-12-18 | ||
| JPJP-P-2021-017633 | 2021-02-05 | ||
| JP2021017633 | 2021-02-05 | ||
| JP2021051107 | 2021-03-25 | ||
| JPJP-P-2021-051107 | 2021-03-25 | ||
| PCT/JP2021/037902 WO2022080413A1 (ja) | 2020-10-14 | 2021-10-13 | ベータコロナウイルス低温馴化株及びワクチン |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20230084180A true KR20230084180A (ko) | 2023-06-12 |
Family
ID=81209182
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237012671A Pending KR20230084180A (ko) | 2020-10-14 | 2021-10-13 | 베타 코로나바이러스 저온순화 주 및 백신 |
| KR1020237012672A Pending KR20230084513A (ko) | 2020-10-14 | 2021-10-13 | 베타 코로나 바이러스 온도 감수성 주 및 백신 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237012672A Pending KR20230084513A (ko) | 2020-10-14 | 2021-10-13 | 베타 코로나 바이러스 온도 감수성 주 및 백신 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20230381296A1 (https=) |
| EP (2) | EP4230742A4 (https=) |
| JP (2) | JPWO2022080414A1 (https=) |
| KR (2) | KR20230084180A (https=) |
| AU (2) | AU2021362585A1 (https=) |
| TW (2) | TW202227619A (https=) |
| WO (2) | WO2022080413A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230084180A (ko) * | 2020-10-14 | 2023-06-12 | 잇판사이단호진한다이비세이부쯔뵤우겐큐우카이 | 베타 코로나바이러스 저온순화 주 및 백신 |
| US20250002871A1 (en) * | 2021-11-08 | 2025-01-02 | The Research Foundation For Microbial Diseases Of Osaka University | Betacoronavirus attenuated strain |
| CN115353552B (zh) * | 2022-08-19 | 2023-07-18 | 山东大学 | 一种降低蛋白质变性温度的方法及其突变体与应用 |
| KR20240124455A (ko) * | 2023-02-08 | 2024-08-19 | (주)파이어니어백신 | 신규한 저온-적응성 약독화 중동호흡기증후군 코로나바이러스 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2529736T3 (es) * | 2003-04-10 | 2015-02-25 | Novartis Vaccines And Diagnostics, Inc. | Composición inmunogénica que comprende una proteína espicular del coronavirus del SARS |
| KR20230084180A (ko) * | 2020-10-14 | 2023-06-12 | 잇판사이단호진한다이비세이부쯔뵤우겐큐우카이 | 베타 코로나바이러스 저온순화 주 및 백신 |
-
2021
- 2021-10-13 KR KR1020237012671A patent/KR20230084180A/ko active Pending
- 2021-10-13 WO PCT/JP2021/037902 patent/WO2022080413A1/ja not_active Ceased
- 2021-10-13 KR KR1020237012672A patent/KR20230084513A/ko active Pending
- 2021-10-13 US US18/031,570 patent/US20230381296A1/en active Pending
- 2021-10-13 EP EP21880152.0A patent/EP4230742A4/en active Pending
- 2021-10-13 EP EP21880151.2A patent/EP4230741A4/en not_active Withdrawn
- 2021-10-13 WO PCT/JP2021/037903 patent/WO2022080414A1/ja not_active Ceased
- 2021-10-13 AU AU2021362585A patent/AU2021362585A1/en not_active Abandoned
- 2021-10-13 AU AU2021361384A patent/AU2021361384A1/en active Pending
- 2021-10-13 JP JP2022557046A patent/JPWO2022080414A1/ja active Pending
- 2021-10-13 JP JP2022557045A patent/JPWO2022080413A1/ja not_active Withdrawn
- 2021-10-13 US US18/031,599 patent/US20230374469A1/en active Pending
- 2021-10-14 TW TW110138222A patent/TW202227619A/zh unknown
- 2021-10-14 TW TW110138223A patent/TWI905295B/zh active
Non-Patent Citations (1)
| Title |
|---|
| 비특허문헌 1 : THE LANCET, VOLUME 396, ISSUE 10255, P887-897, SEPTEMBER 26, 2020 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4230742A1 (en) | 2023-08-23 |
| AU2021361384A1 (en) | 2023-06-01 |
| WO2022080414A1 (ja) | 2022-04-21 |
| AU2021362585A1 (en) | 2023-06-01 |
| EP4230741A4 (en) | 2025-03-26 |
| TW202227619A (zh) | 2022-07-16 |
| WO2022080413A1 (ja) | 2022-04-21 |
| TWI905295B (zh) | 2025-11-21 |
| AU2021361384A9 (en) | 2024-09-12 |
| EP4230741A1 (en) | 2023-08-23 |
| EP4230742A4 (en) | 2025-06-18 |
| US20230381296A1 (en) | 2023-11-30 |
| JPWO2022080413A1 (https=) | 2022-04-21 |
| US20230374469A1 (en) | 2023-11-23 |
| KR20230084513A (ko) | 2023-06-13 |
| TW202227620A (zh) | 2022-07-16 |
| JPWO2022080414A1 (https=) | 2022-04-21 |
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| Date | Code | Title | Description |
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| PA0105 | International application |
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