KR20230077574A - Health functional food using medicinal herbs and manufacturing method thereof - Google Patents
Health functional food using medicinal herbs and manufacturing method thereof Download PDFInfo
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Abstract
Description
본 발명은 산약초를 이용한 건강기능식품 및 그의 제조방법에 관한 것이다. 보다 구체적으로는 산양산삼 등의 산약초를 활용한 건강기능식품 및 그의 제조방법에 관한 것이다.The present invention relates to a health functional food using a mountain herb and a method for manufacturing the same. More specifically, it relates to health functional foods using wild herbs such as wild ginseng and a method for manufacturing the same.
산양산삼은 오가피과에 속하며 다년생 초목인 인삼(Panax ginseng)이 산간의 삼림하의 야생상태에서 자연적으로 성장한 산삼의 씨앗이나 유삼을 인위적으로 산에서 재배한 것을 말하며 이들을 산양산삼이라 한다. 또한 예로부터 야생에서 자생한 산삼은 최고의 산삼으로 쳤다. 인삼의 경우에는 대부분 노두(머리 부분)가 3-7개 정도이나 산양산삼은 연령에 따라 그 이상인 것이 많으며 인삼의 뿌리는 굵고 짧으나 산양산삼은 길고 가늘다. 산양산삼은 여러 효능면에서 재배 인삼보다 효과가 더 높은 것으로 알려져 있다.Mountain wild ginseng belongs to the family Ogapiaceae, and refers to the artificially cultivated wild ginseng seeds or young ginseng in the mountains, where Panax ginseng, a perennial plant, naturally grew in the wild under forests in the mountains. In addition, wild ginseng, which has grown naturally in the wild since ancient times, has been regarded as the best wild ginseng. In the case of ginseng, most of the outcrops (head part) are about 3-7, but wild wild ginseng has more than that depending on the age, and the root of ginseng is thick and short, but wild wild ginseng is long and thin. Sanyang wild ginseng is known to be more effective than cultivated ginseng in terms of various efficacies.
사포닌은 식물계에 널리 분포하고 있는 트리텔펜과 스테로이드계 배당체 화합물의 총칭이다. 사포닌의 뜻은 라틴어의 sapo(비누)에서 유래되어 이것을 물과 함께 진탕하면 거품을 형성하는 천연계면활성제이다. 삼(ginseng)의 사포닌인 진세노사이드를 함유한 산양산삼은 한약처방전에서 천연 자연 산삼 다음으로 효능을 높이 평가하고 있다. 또한 재배인삼과 비교하였을 시 진세노사이드 함량이 높다고 보고되어져 있으며 재배된 인삼보다 효능 또한 뛰어남이 알려져 있다. 특히 산양산삼은 면역계에 영향을 미쳐 면역증강의 약리효과가 우수하다고 알려져 있다.Saponin is a generic term for triterpene and steroid-based glycoside compounds widely distributed in the plant kingdom. The meaning of saponin is derived from sapo (soap) in Latin, and is a natural surfactant that forms foam when shaken with water. Sanyang wild ginseng, which contains ginsenoside, a saponin of ginseng, is highly evaluated for efficacy next to natural wild ginseng in herbal medicine prescriptions. In addition, it has been reported that the ginsenoside content is higher when compared to cultivated ginseng, and the efficacy is also known to be superior to that of cultivated ginseng. Sanyang wild ginseng, in particular, is known to have excellent pharmacological effects in enhancing immunity by influencing the immune system.
최근 삼(ginseng)에 대한 선호도가 인삼에서 무농약 산양산삼 뿐만 아니라 홍삼으로 변화하고 있다.Recently, the preference for ginseng is changing from ginseng to pesticide-free wild ginseng as well as red ginseng.
홍삼의 제조과정에서 발생하는 열에 의해 인삼에는 존재하지 않는 홍삼만의 특유 성분인 진세노사이드 Rg2, Rg3, Rhl, Rh2 등의 사포닌 성분이 새로이 생성되며, 이러한 홍삼 특유 사포닌은 암예방 작용, 암세포 성장억제 작용, 혈압 강하작용, 뇌신경 세포 보호 및 학습능력 개선작용, 항혈전 작용, 항산화 작용 등이 있다고 알려져 있어 이에 대한 홍삼만의 탁월한 약리 효능을 기대할 수 있다.The heat generated during the manufacturing process of red ginseng creates new saponins such as ginsenosides Rg2, Rg3, Rhl, and Rh2, which are unique components of red ginseng that do not exist in ginseng. It is known to have inhibitory action, blood pressure lowering action, brain nerve cell protection and learning ability improvement action, antithrombotic action, and antioxidant action.
소비자들의 건강에 대한 관심이 높아짐에 따라 액상차 형태의 건강기능식품에 대한 개발이 많이 이루어졌다. 그러나, 액상차 형태의 건강기능식품은 휴대성 및 보관성의 문제가 있다. 산양산삼 및 홍삼을 주성분으로 함유하면서도 추가 재료의 적절한 배합을 통해 새로운 형태의 건강기능식품을 개발할 필요가 있다.As consumers' interest in health has increased, many developments have been made for health functional foods in the form of liquid tea. However, health functional food in the form of liquid tea has problems in portability and storage. It is necessary to develop a new type of health functional food that contains wild wild ginseng and red ginseng as the main ingredients, but also properly mixes additional ingredients.
본 발명의 일 측면은 면역력 증진, 피로회복, 숙취해소 기능이 개선된 정제 형태의 산약초를 이용한 건강기능식품 및 이를 제조하기 위한 적절한 방법을 제시하고자 한다.One aspect of the present invention is to propose a health functional food using mountain medicinal herbs in tablet form with improved immunity enhancement, fatigue recovery, and hangover relief functions, and an appropriate method for manufacturing the same.
그러나, 본 발명이 해결하고자 하는 과제는 이상에서 언급한 과제로 제한되지 않으며, 언급되지 않은 또 다른 과제들은 아래의 기재로부터 당업자에게 명확하게 이해될 수 있을 것이다.However, the problem to be solved by the present invention is not limited to the above-mentioned problem, and other problems not mentioned will be clearly understood by those skilled in the art from the description below.
상기와 같은 목적을 달성하기 위하여, 본 발명의 일 측면은, 삼(ginseng) 분말, 밀크씨슬, 호박산, 흑마늘농축 분말, 울금추출물 분말, 헛개나무열매추출물 분말, 영지버섯자실체추출물 분말, 아미노산혼합 분말 및 타우린으로 이루어진 제1 조성물 66.5~67 중량부; 판토텐산칼슘, 비타민B6 염산염, 비타민B1 염산염 및 비타민B2으로 이루어진 제2 조성물 1.8~1.9 중량부; 그리고, 결정셀룰로오스, 베타인, 이산화규소, 스테아린산마그네슘, 카복시메틸셀룰로오스 칼슘, 히드록시프로필메틸셀룰로오스 및 글리세린지방산에스테르로 이루어진 식품첨가물 31.2~31.4 중량부를 포함하여 이루어지는, 산약초를 이용한 건강기능식품을 제공한다.In order to achieve the above object, one aspect of the present invention is hemp (ginseng) powder, milk thistle, succinic acid, black garlic concentrate powder, turmeric extract powder, raisin raisin fruit extract powder, ganoderma lucidum fruiting body extract powder, amino acid mixture 66.5 to 67 parts by weight of a first composition consisting of powder and taurine; 1.8 to 1.9 parts by weight of a second composition consisting of calcium pantothenate, vitamin B6 hydrochloride, vitamin B1 hydrochloride and vitamin B2; In addition, 31.2 to 31.4 parts by weight of food additives composed of crystalline cellulose, betaine, silicon dioxide, magnesium stearate, carboxymethyl cellulose calcium, hydroxypropyl methyl cellulose and glycerin fatty acid ester, providing health functional food using acid herbs do.
본 발명의 다른 측면은 삼(ginseng) 분말, 밀크씨슬, 호박산, 흑마늘농축 분말, 울금추출물 분말, 헛개나무열매추출물 분말, 영지버섯자실체추출물 분말, 아미노산혼합 분말, 타우린, 판토텐산칼슘, 비타민B6 염산염, 비타민B1 염산염, 비타민B2, 결정셀룰로오스, 베타인, 스테아린산마그네슘 및 카복시메틸셀룰로오스 칼슘을 혼합하여 제1차 혼합물을 준비하는 단계; 상기 제1차 혼합물에 주정을 투입하고 연합하여 과립을 만드는 단계; 상기 연합 후 건조하여 수분함량이 5% 이내로 조절하는 단계; 상기 건조 후 이산화규소를 투입하여 제2차 혼합물을 준비하는 단계; 상기 제2차 혼합물을 타정하여 정제를 만드는 단계; 히드록시프로필메틸셀룰로오스 및 글리세린지방산에스테르를 주정에 용해하여 코팅액을 준비하는 단계; 및 상기 정제에 상기 코팅액을 분사하여 코팅하고 건조하는 단계를 포함하는, 산약초를 이용한 건강기능식품의 제조방법을 제공한다.Another aspect of the present invention is hemp (ginseng) powder, milk thistle, succinic acid, black garlic concentrated powder, turmeric extract powder, raisin raisin fruit extract powder, ganoderma lucidum fruiting body extract powder, amino acid mixture powder, taurine, calcium pantothenate, vitamin B6 hydrochloride preparing a first mixture by mixing vitamin B1 hydrochloride, vitamin B2, crystalline cellulose, betaine, magnesium stearate, and carboxymethylcellulose calcium; Injecting alcohol into the first mixture and combining them to form granules; Drying after the coalescence to adjust the moisture content to within 5%; Preparing a second mixture by adding silicon dioxide after drying; Tableting the second mixture into tablets; preparing a coating solution by dissolving hydroxypropylmethylcellulose and glycerin fatty acid ester in alcohol; And it provides a method for producing a health functional food using acid herbs, comprising spraying the coating liquid on the tablets to coat and dry them.
본 발명에 의하면, 산양산삼을 비롯한 산약초의 효능을 증진할 수 있으면서도 휴대성과 보관성이 우수한 알약 형태의 건강기능식품을 통해 면역력 증진, 피로회복, 숙취해소에 도움을 줄 수 있다.According to the present invention, it is possible to improve immunity, recover from fatigue, and help relieve hangover through a health functional food in the form of a pill with excellent portability and storability while enhancing the efficacy of mountain medicinal herbs including wild wild ginseng.
도 1은 본 발명의 일 실시예에 따른 건강기능식품을 제조하는 공정도이다.1 is a process chart for manufacturing a health functional food according to an embodiment of the present invention.
본원이 속하는 기술 분야에서 통상의 지식을 가진 자가 용이하게 실시할 수 있도록 본원의 실시예를 상세히 설명한다. 그러나 본원은 여러 가지 상이한 형태로 구현될 수 있으며 여기에서 설명하는 실시예에 한정되지 않는다.The embodiments of the present application will be described in detail so that those skilled in the art can easily practice them. However, the present disclosure may be implemented in many different forms and is not limited to the embodiments described herein.
본원 명세서 전체에서, 어떤 부분이 어떤 구성요소를 "포함"한다고 할 때, 이는 특별히 반대되는 기재가 없는 한 다른 구성요소를 제외하는 것이 아니라 다른 구성 요소를 더 포함할 수 있는 것을 의미한다. Throughout the present specification, when a certain component is said to "include", it means that it may further include other components without excluding other components unless otherwise stated.
본 명세서에서 "구성된다" 또는 "포함한다" 등의 용어는 명세서 상에 기재된 여러 구성 요소들, 또는 여러 단계들을 반드시 모두 포함하는 것으로 해석되지 않아야 하며, 그 중 일부 구성 요소들 또는 일부 단계들은 포함되지 않을 수도 있고, 또는 추가적인 구성 요소 또는 단계들을 더 포함할 수 있는 것으로 해석되어야 한다.In this specification, terms such as "consisting of" or "comprising" should not be construed as necessarily including all of the various components or steps described in the specification, and some of the components or steps are included. It should be construed that it may not be, or may further include additional components or steps.
본 명세서에서 화학물질의 함유량을 나타내기 위하여 사용하는 퍼센트(%) 기호는 해당 화학물질의 농도를 표시하기 위한 것으로서 중량%를 의미하는 것일 수 있다. 가령, 98%의 A알코올이란 해당 물질 100g 중에 A알코올 98g과 A알코올 이외의 물질 2g이 섞여 있는 것으로 이해할 수 있다.In this specification, the percent (%) symbol used to indicate the content of a chemical substance is to indicate the concentration of the chemical substance and may mean weight%. For example, 98% of alcohol A can be understood as a mixture of 98 g of alcohol A and 2 g of substances other than alcohol A in 100 g of the substance.
본 발명은 산양산삼 및 홍삼과 같은 산약초의 유효한 성분을 활용하여 피로회보고가 숙취해소에 효과적인 알약 형태의 건강기능식품을 제공하는 것이다.The present invention is to provide a health functional food in the form of pills that is effective in relieving hangover fatigue by utilizing effective ingredients of mountain herbs such as wild wild ginseng and red ginseng.
상기 목적을 달성하기 위하여 본 발명에서는 삼(ginseng) 분말, 밀크씨슬, 호박산, 흑마늘농축 분말, 울금추출물 분말, 헛개나무열매추출물 분말, 영지버섯자실체추출물 분말, 아미노산혼합 분말 및 타우린으로 이루어진 제1 조성물 66.5~67 중량부; 판토텐산칼슘, 비타민B6 염산염, 비타민B1 염산염 및 비타민B2으로 이루어진 제2 조성물 1.8~1.9 중량부; 그리고, 결정셀룰로오스, 베타인, 이산화규소, 스테아린산마그네슘, 카복시메틸셀룰로오스 칼슘, 히드록시프로필메틸셀룰로오스 및 글리세린지방산에스테르로 이루어진 식품첨가물 31.2~31.4 중량부를 포함하여 이루어지는, 산약초를 이용한 건강기능식품을 제공한다.In order to achieve the above object, in the present invention, a first composition consisting of ginseng powder, milk thistle, succinic acid, black garlic concentrated powder, turmeric extract powder, hovenia fruit extract powder, ganoderma lucidum fruiting body extract powder, amino acid mixture powder and taurine 66.5-67 parts by weight of the composition; 1.8 to 1.9 parts by weight of a second composition consisting of calcium pantothenate, vitamin B6 hydrochloride, vitamin B1 hydrochloride and vitamin B2; In addition, 31.2 to 31.4 parts by weight of food additives composed of crystalline cellulose, betaine, silicon dioxide, magnesium stearate, carboxymethyl cellulose calcium, hydroxypropyl methyl cellulose and glycerin fatty acid ester, providing health functional food using acid herbs do.
상기 제1 조성물은 본 발명의 건강기능식품에 있어서 주요 원료이며, 면역력 증진, 피로회복, 숙취해소 등의 효과를 발휘하도록 한다.The first composition is a main raw material in the health functional food of the present invention, and is intended to exert effects such as immunity enhancement, fatigue recovery, and hangover relief.
상기 삼(ginseng) 분말로는 산양삼 분말 또는 홍삼 분말을 들 수 있으나, 이에 제한되지 않고 인삼 분말, 흑삼 분말 등을 배제하려는 것은 아니다. 삼(ginseng)의 산약초는 사포닌의 일종인 진세노사이드 및 항산화 물질인 폴리페놀이 들어있어서 혈관, 소화기, 호흡기 건강에 도움이 되며, 폐 기능을 도우며 진액을 생성한다. 또한 삼은 이러한 성분들을 통해 대뇌피질흥분과 억제, 평형, 항노화, 면역증강, 심장수축, 고혈당억제, 항암, 해독작용 등 약리작용의 효과를 지닌다.The ginseng powder may include wild ginseng powder or red ginseng powder, but is not limited thereto and is not intended to exclude ginseng powder, black ginseng powder, and the like. The mountain herb of ginseng contains ginsenoside, a type of saponin, and polyphenol, an antioxidant, which is helpful for blood vessel, digestive, and respiratory health, helps lung function, and produces essence. In addition, ginseng has pharmacological effects such as excitation and inhibition of cerebral cortex, equilibrium, anti-aging, immunity enhancement, heart contraction, hyperglycemia inhibition, anti-cancer, and detoxification through these components.
상기 밀크씨슬의 실리마린(Silymarin) 성분이 활성 산소로부터 간세포를 보호하는 등 항산화작용을 한다. 간 GOT, GPT, ALP가 증가하고, 혈중 GOT, GPT, ALP는 감소하는 등 실리마린은 간에서 glutathione 생성을 증가시켜 간독성을 억제하고 RNA 효소 활성을 통해 리보조옴 단백질 합성을 촉진하여 간 기능을 재생한다. 또한 free radical에 의한 간 세포막의 지질 산화를 감소시켜 간 손상을 억제한다. 안전성을 고려하여 일일섭취량을 실리마린으로서 130mg으로 권장되고 있다.The silymarin component of the milk thistle acts as an antioxidant, such as protecting liver cells from active oxygen. Increased liver GOT, GPT, and ALP, decreased blood GOT, GPT, and ALP. Silymarin increases glutathione production in the liver to suppress hepatotoxicity and promotes ribosome protein synthesis through RNA enzyme activity to regenerate liver function. do. In addition, it inhibits liver damage by reducing lipid oxidation of liver cell membranes caused by free radicals. Considering safety, the daily intake is recommended as 130mg as silymarin.
상기 호박산은 석신산(succinic acid)으로도 불리며, 세포의 물질대사(특히 ATP 형성)와 세포 기능의 조절을 연결시킨다. 또한, 식품 및 음료 산업에서 주로 산도 조절제로 사용되며, 이미 식품첨가물 및 식이 보충제로 미국식품의약국의 인정을 받은 화합물이다.The succinic acid, also called succinic acid, links cellular metabolism (particularly ATP formation) with regulation of cellular functions. In addition, it is mainly used as an acidity regulator in the food and beverage industry, and is a compound already recognized by the US Food and Drug Administration as a food additive and dietary supplement.
상기 흑마늘농축 분말 관련하여, 흑마늘은 70℃, 습도 85~90% 정도의 환경에서 숙성 발효 과정을 거치게 되면서 만들어지며, 기존 마늘보다 더 많은 영양분을 응축하고 있으면서 새로운 성분을 발생시키기도 한다. 흑마늘농축 분말은 숙성된 흑마늘의 유효성분을 액상추출하고 농축/결정화해서 만들 수 있다. 흑마늘 효능은 알리신과 S-아릴시스테인, 멜라노이딘 등의 성분에 의해 발생된다. 알리신은 심혈관 질환, 뇌혈관 질환, 당뇨, 암, 살균 등이 효과를 가지며, 비타민 B1의 흡수가 될 수 있도록 도와준다. 흑마늘로 발효되는 과정에서 S-아릴시스테인이라는 새로운 성분이 발생하며 폴리페놀의 일종으로 활성산소에 대한 항산화 효과가 있다. 멜라노이딘은 마늘이 발효가 될 때 아미노산과 당분이 반응을 하게 되어 흑색으로 변하며 이는 멜라노이딘이라는 화합물에 의해 나타나는 색상이며 생마늘에는 없는 강력한 항산화 작용을 한다. Regarding the black garlic concentrated powder, black garlic is made by undergoing a maturation fermentation process in an environment of 70 ° C. and humidity of about 85 to 90%, condensing more nutrients than conventional garlic while generating new ingredients. Concentrated black garlic powder can be made by liquid extraction and concentration/crystallization of active ingredients of aged black garlic. The efficacy of black garlic is caused by components such as allicin, S-arylcysteine, and melanoidin. Allicin has effects on cardiovascular disease, cerebrovascular disease, diabetes, cancer, and sterilization, and helps to absorb vitamin B1. In the process of fermentation with black garlic, a new component called S-arylcysteine is generated, and as a kind of polyphenol, it has an antioxidant effect against active oxygen. When garlic is fermented, amino acids and sugars react and turn black, which is the color shown by a compound called melanoidin, and has a strong antioxidant action that raw garlic does not have.
상기 울금추출물 분말 관련하여, 울금은 생강과에 속하는 다년생 초본으로 항산화작용, 항균성, 항암성, 항돌연변이성, 항종양성에 관한 연구가 보고되고 있다. Regarding the turmeric extract powder, turmeric is a perennial herb belonging to the ginger family, and studies on antioxidant activity, antibacterial activity, anticancer activity, antimutagenicity, and antitumor activity have been reported.
상기 헛개나무열매추출물 분말 관련하여, 헛개나무 열매 추출 분말은 알코올로 인한 간 손상으로부터 간을 보호하는 데 도움을 줄 수 있는 기능성 원료로, 플라보노이드(flavonoid) 성분은 알코올 분해 효소의 활성을 촉진하고 항산화, 항염증 효과를 낸다.Regarding the Hovenia fruit extract powder, the Hovenia fruit extract powder is a functional raw material that can help protect the liver from alcohol-induced liver damage, and the flavonoid component promotes the activity of alcohol decomposition enzymes and antioxidants. , has an anti-inflammatory effect.
상기 영지버섯자실체추출물 분말과 관련하여, 영지버섯자실체추출물은 영지버섯의 자실체를 열수로 추출한 후 여과 농축하여 식용에 적합하도록 한 것을 말하며, 베타글루칸이 1% 이상 함유되어 있다. 영지버섯 자실체 추출물은 혈중 피브리노겐 함량을 증가시키고 콜레스테롤, 중성지방을 감소시키며 혈전 형성 및 혈소판 응집 속도를 감소시켜 혈행 개선에 도움을 준다.Regarding the Ganoderma lucidum fruiting body extract powder, the Ganoderma lucidum fruiting body extract refers to a product obtained by extracting the fruiting body of Ganoderma lucidum with hot water and then filtering and concentrating to make it suitable for consumption, and contains 1% or more of beta-glucan. Ganoderma lucidum fruiting body extract helps to improve blood circulation by increasing fibrinogen content in the blood, reducing cholesterol and neutral fat, and reducing the rate of blood clot formation and platelet aggregation.
상기 아미노산혼합 분말은 L-페닐알라닌, L-로이신, L-메티오닌, L-라이신염산염, 팔라티노스, L-히스티딘, L-이소로이신, L-발린 및 L-트립토판이 혼합되어 이루어진다. 혼합비율은 임의로 조절 가능하다. 아미노산은 근력과 지구력을 높여 주고, 신체 능력을 향상시킨다. 근육 분해를 막고, 오랫동안 에너지를 낼 수 있게 해주며, 근육 피로해소에 도움을 준다. 뇌 신경세포와 신경전달물질을 만드는 데도 아미노산이 필요하다The amino acid mixture powder is made by mixing L-phenylalanine, L-leucine, L-methionine, L-lysine hydrochloride, palatinose, L-histidine, L-isoleucine, L-valine and L-tryptophan. The mixing ratio can be arbitrarily adjusted. Amino acids increase muscle strength and endurance, and improve physical performance. It prevents muscle breakdown, allows you to generate energy for a long time, and helps relieve muscle fatigue. Amino acids are also needed to make brain neurons and neurotransmitters.
상기 타우린은 아미노산의 일종이며, 지방의 유화와 흡수를 돕고, 콜레스테롤과 중성지방을 감소시키고, 알코올에 의한 숙취를 감소시키며, 여러 종류의 라디칼을 포착하는 항산화제로 작용한다.The taurine is a kind of amino acid, helps emulsify and absorb fat, reduces cholesterol and triglycerides, reduces alcohol-induced hangover, and acts as an antioxidant that captures various types of radicals.
상기 제2 조성물은 비타민B 복합체 영양소로 이루어지는 보충제이다. 비타민 B군은 세포 대사에서 중요한 역할을 수행하는 수용성 비타민들이다. 비타민 B들은 수용성이므로 체내에 축적되지 않고 배출되므로 주기적이고 지속적인 섭취가 요구된다. 상기 제1 조성물들의 세포대사 활동이 원활하게 이루어지도록 돕는다.The second composition is a supplement composed of vitamin B complex nutrients. The B vitamins are water-soluble vitamins that play an important role in cellular metabolism. Since B vitamins are water-soluble, they are excreted without accumulation in the body, so periodic and continuous intake is required. It helps the cellular metabolic activities of the first compositions to be performed smoothly.
상기 판토텐산칼슘은 판토텐산(비타민B5)의 칼슘염으로 체내에서 성장과 건강유지에 필요하다. 비타민 B-복합체 영양소 중 하나로, 지방, 탄수화물, 단백질 대사와 에너지 생성에 필요하며, 간장 기능장해, 피로, 중독 등의 치료에 활용될 수 있다.The calcium pantothenate is a calcium salt of pantothenic acid (vitamin B5), which is necessary for growth and health maintenance in the body. As one of the vitamin B-complex nutrients, it is necessary for fat, carbohydrate, and protein metabolism and energy production, and can be used to treat liver dysfunction, fatigue, and addiction.
상기 비타민B6 염산염은 피리독신 염산염 등으로 불리우는 수용성 비타민으로, 각종 신경, 피부 질환을 예방하며, 구토증을 가라앉히고 노화를 방지하는 핵산의 합성 및 이뇨작용을 촉진한다. 결핍증상은 피부염, 구내염, 구순염, 간질성 혼수, 설염, 우울증, 뇌파계의 이상 등을 들 수 있다.The vitamin B6 hydrochloride is a water-soluble vitamin called pyridoxine hydrochloride, etc., which prevents various nerve and skin diseases, relieves vomiting, and promotes nucleic acid synthesis and diuretic action to prevent aging. Deficiency symptoms include dermatitis, stomatitis, cheilitis, epileptic coma, glossitis, depression, and brain wave abnormalities.
상기 비타민B1 염산염(Thiamine Hydrochloride) 관련하여, 비타민B1은 피로포스페이트의 조효소로 탄수화물과 분지상 아미노산(류신, 아이소류신, 발린)의 대사에 관여한다. 비타민B1 부족시 각기병, 신경질환, 신경염, 알코올성 건망증후군 등의 대사장애를 일으킨다.Regarding the vitamin B1 hydrochloride, vitamin B1 is a coenzyme of pyrophosphate and is involved in the metabolism of carbohydrates and branched amino acids (leucine, isoleucine, and valine). Lack of vitamin B1 causes metabolic disorders such as beriberi, neurological diseases, neuritis, and alcoholic amnesia syndrome.
상기 비타민B2(Riboflavin, 리보플라빈)는 체내 에너지 생성에 필요하며, 리보플라빈 부족으로 인한 결핍증 증상으로는 구각염, 구순염, 설염 및 빈혈과 함께 입이나 코 주위의 안면부, 음낭, 외음부에서 나타나는 지루성 피부염이 대표적이다.The vitamin B2 (Riboflavin, riboflavin) is required for energy production in the body, and deficiency symptoms caused by a lack of riboflavin include angular cheilitis, cheilitis, glossitis, and anemia, as well as seborrheic dermatitis in the facial area around the mouth or nose, scrotum, and vulva. am.
상기 식품첨가물은 상기 제1 조성물 및 상기 제2 조성물 이외에 본 건강기능식품의 정제 형성 공정에 기여하거나 알약 형태의 표면에 추가적인 기능성 물질을 함께 부가하여 제품의 효능을 증진시키기 위한 부가적 물질들이다.The food additives, in addition to the first composition and the second composition, are additional materials that contribute to the tablet forming process of the health functional food or enhance the efficacy of the product by adding additional functional materials to the surface of the pill.
상기 결정셀룰로오스는 식품첨가물의 하나로서, 정제 제품 및 각종 제품에 유화제, 안정제 등의 역할로 필요하다. The crystalline cellulose is one of the food additives, and is required as an emulsifier, stabilizer, etc. in refined products and various products.
상기 베타인은 메틸기를 세 개 가진 아미노산으로서 식품의 감칠맛 성분이다. 메틸기 공여를 통해 메싸이오닌 합성을 촉진하여 항지간작용 및 혈압 강하, 항혈당작용, 시력회복, 해독작용, 세포 복제 기능 등의 작용을 한다. 알코올로 인해 손상된 지방간을 치료하는 항지간작용 외에도 카르니틴(carnitine)을 생성하여 신장을 보호하는 역할도 한다. 간 해독 작용을 촉진하며 항암 작용을 한다.The betaine is an amino acid having three methyl groups and is a umami component of food. It promotes methionine synthesis through donation of methyl group, and acts as an anti-lipid action, blood pressure lowering, anti-glycemic action, vision recovery, detoxification, and cell replication. In addition to the anti-fat liver action that treats fatty liver damaged by alcohol, it also plays a role in protecting the kidneys by producing carnitine. It promotes liver detoxification and has anticancer activity.
상기 이산화규소는 고결방지제로 사용될 수 있다.The silicon dioxide may be used as an anti-caking agent.
상기 스테아린산마그네슘은 알약을 단단하게 유지시켜 주는 역할을 하며, 식품의 점착성이나 점도를 증가시키고 식품의 물성 및 촉감을 향상시키기 위한 식품첨가물로 사용된다.The magnesium stearate serves to keep the pills hard, increases the stickiness or viscosity of food, and is used as a food additive to improve physical properties and texture of food.
상기 카복시메틸셀룰로오스 칼슘은 증점제, 안정제로 사용된다.The carboxymethyl cellulose calcium is used as a thickener and stabilizer.
상기 히드록시프로필메틸셀룰로오스 (HPMC)는 식품, 코팅, 결합제로 사용된다.The hydroxypropylmethylcellulose (HPMC) is used as a food, coating, and binder.
상기 글리세린지방산에스테르는 글리세린에 지방산이 에스테르 결합한 것으로 글리세리드를 말하며, 유화제로 사용된다.The glycerin fatty acid ester refers to glyceride obtained by ester bonding of fatty acids to glycerin, and is used as an emulsifier.
본 건강기능식품은 상기 제1 조성물, 상기 제2 조성물 및 상기 식품첨가물을 포함하여 이루어지며, 중량비율로 66.5~67 : 1.8~1.9 : 31.2~31.4로 구성될 수 있다.This health functional food is made up of the first composition, the second composition and the food additives, and may be composed of 66.5 to 67: 1.8 to 1.9: 31.2 to 31.4 in weight ratio.
즉, 상기 제1 조성물 66.5~67 중량부에 대하여 상기 제2 조성물이 1.8~1.9 중량부이고, 상기 식품첨가물이 31.2~31.4 중량부로 포함될 수 있다.That is, based on 66.5 to 67 parts by weight of the first composition, the second composition may be 1.8 to 1.9 parts by weight, and the food additive may be included in 31.2 to 31.4 parts by weight.
본 발명의 일 구현예에 따르면, 본 발명의 건강기능식품은 상기 삼(ginseng) 분말 10.5 중량%, 상기 밀크씨슬 20.313 중량%, 상기 호박산 30 중량%, 상기 흑마늘농축 분말 1 중량%, 상기 울금추출물 분말 1 중량%, 상기 헛개나무열매추출물 분말 1 중량%, 상기 영지버섯자실체추출물 분말 1 중량%, 상기 아미노산혼합 분말 1 중량%, 상기 타우린 1 중량%, 상기 판토텐산칼슘 0.99 중량%, 상기 비타민B6 염산염 0.33 중량%, 상기 비타민B1 염산염 0.28 중량%, 상기 비타민B2 0.25 중량%, 상기 결정셀룰로오스 21.687 중량%, 상기 베타인 5 중량%, 상기 이산화규소 1.8 중량%, 상기 스테아린산마그네슘 1 중량%, 상기 카복시메틸셀룰로오스 칼슘 1 중량%, 상기 히드록시프로필메틸셀룰로오스 0.77 중량%, 및 상기 글리세린지방산에스테르 0.08 중량%로 포함할 수 있다.According to one embodiment of the present invention, the health functional food of the present invention comprises 10.5% by weight of the hemp powder, 20.313% by weight of the milk thistle, 30% by weight of the succinic acid, 1% by weight of the black garlic concentrated powder, and the turmeric. 1% by weight of extract powder, 1% by weight of raisin fruit extract powder, 1% by weight of ganoderma lucidum fruiting body extract powder, 1% by weight of amino acid mixture powder, 1% by weight of taurine, 0.99% by weight of calcium pantothenate, and vitamin B6 0.33% by weight of hydrochloride, 0.28% by weight of vitamin B1 hydrochloride, 0.25% by weight of vitamin B2, 21.687% by weight of crystalline cellulose, 5% by weight of betaine, 1.8% by weight of silicon dioxide, 1% by weight of magnesium stearate, 1% by weight of carboxylate 1% by weight of methylcellulose calcium, 0.77% by weight of the hydroxypropylmethylcellulose, and 0.08% by weight of the glycerin fatty acid ester.
이때, 상기 삼(ginseng) 분말은 산양산삼 분말과 홍삼 분말이 중량비율로 1 : 20로 혼합된 것일 수 있다. 즉 상기 삼(ginseng) 분말 10.5 중량% 중에는 산양산삼 분말이 0.5 중량%이고 홍삼 분말이 10 중량%로 혼합되어 있을 수 있다.At this time, the ginseng powder may be a mixture of wild wild ginseng powder and red ginseng powder in a weight ratio of 1:20. That is, in 10.5% by weight of the ginseng powder, 0.5% by weight of wild ginseng powder and 10% by weight of red ginseng powder may be mixed.
본 발명의 다른 구현예에 따르면, 본 발명이 건강기능식품은 상기 삼(ginseng) 분말 0.5 중량%, 상기 밀크씨슬 20.313 중량%, 상기 호박산 40 중량%, 상기 흑마늘농축 분말 1 중량%, 상기 울금추출물 분말 1 중량%, 상기 헛개나무열매추출물 분말 1 중량%, 상기 영지버섯자실체추출물 분말 1 중량%, 상기 아미노산혼합 분말 1 중량%, 상기 타우린 1 중량%, 상기 판토텐산칼슘 0.99 중량%, 상기 비타민B6 염산염 0.33 중량%, 상기 비타민B1 염산염 0.28 중량%, 상기 비타민B2 0.25 중량%, 상기 결정셀룰로오스 21.687 중량%, 상기 베타인 5 중량%, 상기 이산화규소 1.8 중량%, 상기 스테아린산마그네슘 1 중량%, 상기 카복시메틸셀룰로오스 칼슘 1 중량%, 상기 히드록시프로필메틸셀룰로오스 0.77 중량%, 및 상기 글리세린지방산에스테르 0.08 중량%로 포함할 수 있다.According to another embodiment of the present invention, the health functional food of the present invention contains 0.5% by weight of the ginseng powder, 20.313% by weight of the milk thistle, 40% by weight of the succinic acid, 1% by weight of the black garlic concentrated powder, and the turmeric. 1% by weight of extract powder, 1% by weight of raisin fruit extract powder, 1% by weight of ganoderma lucidum fruiting body extract powder, 1% by weight of amino acid mixture powder, 1% by weight of taurine, 0.99% by weight of calcium pantothenate, and vitamin B6 0.33% by weight of hydrochloride, 0.28% by weight of vitamin B1 hydrochloride, 0.25% by weight of vitamin B2, 21.687% by weight of crystalline cellulose, 5% by weight of betaine, 1.8% by weight of silicon dioxide, 1% by weight of magnesium stearate, 1% by weight of carboxylate 1% by weight of methylcellulose calcium, 0.77% by weight of the hydroxypropylmethylcellulose, and 0.08% by weight of the glycerin fatty acid ester.
이때, 상기 삼(ginseng) 분말은 산양산삼 분말일 수 있다.At this time, the hemp (ginseng) powder may be wild ginseng powder.
상기 건강기능식품은 정제 형태 또는 알약 형태일 수 있으며, 그 제조 공정을 후술하기로 한다. 도 1을 참조하면 제조 공정은 간략히 원료 준비 → 제 1차 혼합 → 연합/건조 → 제2차 혼합 → 타정/정제 → 코팅 순으로 이루어진다.The health functional food may be in tablet form or pill form, and the manufacturing process thereof will be described later. Referring to FIG. 1, the manufacturing process is briefly performed in the order of raw material preparation → first mixing → kneading/drying → second mixing → tableting/refining → coating.
먼저, 삼(ginseng) 분말, 밀크씨슬, 호박산, 흑마늘농축 분말, 울금추출물 분말, 헛개나무열매추출물 분말, 영지버섯자실체추출물 분말, 아미노산혼합 분말, 타우린, 판토텐산칼슘, 비타민B6 염산염, 비타민B1 염산염, 비타민B2, 결정셀룰로오스, 베타인, 스테아린산마그네슘 및 카복시메틸셀룰로오스 칼슘을 혼합하여 제1차 혼합물을 준비한다. First, hemp (ginseng) powder, milk thistle, succinic acid, black garlic concentrate powder, turmeric extract powder, hovenia fruit extract powder, ganoderma lucidum fruiting body extract powder, amino acid mixture powder, taurine, calcium pantothenate, vitamin B6 hydrochloride, vitamin B1 hydrochloride , Vitamin B2, crystalline cellulose, betaine, magnesium stearate and carboxymethylcellulose calcium are mixed to prepare a first mixture.
상기 제1차 혼합물에 알코올 농도 70% 이상의 주정을 투입하고 연합하여 과립을 만든다. 이때 투입되는 상기 주정 1 중량부에 대해 상기 제1차 혼합물은 5 중량부를 사용할 수 있다. 예를 들어, 연합기에 상기 제1차 혼합물 70kg을 넣고 70% 주정 14kg을 넣어 5분간 연합할 수 있다. Add alcohol having an alcohol concentration of 70% or more to the first mixture and combine to form granules. At this time, 5 parts by weight of the first mixture may be used for 1 part by weight of the alcohol added. For example, 70 kg of the first mixture may be put into a coalescer and 14 kg of 70% alcohol may be fed into the coalescing machine for 5 minutes.
상기 연합 공정을 거친 후 건조한다. 상기 연합 후 건조하는 단계는 55~65 ℃에서 9~11 시간 진행할 수 있다. 구체적으로 건조기 채반에 4kg식 소분하여 담고, 미리 60℃로 예열한 건조기에서 10시간 동안 건조한다.After the coalescence process, it is dried. The step of drying after the coalescence may proceed for 9 to 11 hours at 55 to 65 ° C. Specifically, 4 kg is subdivided into a dryer tray, and dried for 10 hours in a dryer preheated to 60 ° C.
상기 건조된 과립물의 수분함량이 5% 이내인 경우, 정립기로 정립한다. 정립 Mesh는 12~16 수준일 수 있다.When the moisture content of the dried granules is less than 5%, they are sized with a sizing machine. The upright mesh may be 12 to 16 levels.
상기 건조 후 이산화규소를 투입하여 제2차 혼합물을 준비한다. 즉, 혼합기에 과립 건조된 혼합물과 이산화규소를 넣고 2차 혼합을 10 분 동안 실시한다.After drying, silicon dioxide is added to prepare a second mixture. That is, the granulated mixture and silicon dioxide are put into a mixer, and secondary mixing is performed for 10 minutes.
상기 제2차 혼합물을 타정하여 정제를 만든다. 경도 4.5kgf을 기준으로 하여 정제를 찍어낸다. 타정품의 무게는 627~645 mg로 유지한다.Tablets are made by tableting the second mixture. Tablets are stamped out based on the hardness of 4.5 kgf. The weight of other products is maintained at 627~645 mg.
히드록시프로필메틸셀룰로오스 및 글리세린지방산에스테르를 주정에 용해하여 코팅액을 미리 준비해 둔다. A coating solution is prepared in advance by dissolving hydroxypropylmethylcellulose and glycerin fatty acid ester in alcohol.
상기 찍어낸 정제에 상기 코팅액을 분사하여 코팅하고 건조한다. 코팅시 팬의 온도를 20~60℃로 유지하면서 건조한다.The coating liquid is sprayed on the stamped tablet, coated, and dried. During coating, dry while maintaining the temperature of the pan at 20 ~ 60 ℃.
또한, 상기 제1차 혼합물을 준비하는 단계 이전에 삼(ginseng) 원료의 유효성분을 액상으로 추출한 후 동결건조하여 삼(ginseng) 분말을 준비하는 단계를 추가로 포함할 수 있다. 이와 같이 액상 추출 후 동결건조하여 분말을 준비하면 산양산삼의 지표물질들에 대한 약용성분(다당류 등) 및 지표물질의 증강을 가져오고 빠른 시간내에 체내 흡수가 되어 복용자들의 만족도가 상승하는 것을 확인하였다.In addition, prior to the step of preparing the first mixture, a step of preparing ginseng powder by extracting the active ingredient of the ginseng raw material in a liquid phase and then freeze-drying it may be further included. In this way, when powder is prepared by freeze-drying after liquid extraction, medicinal ingredients (polysaccharides, etc.) and marker substances for marker substances of wild wild ginseng are enhanced, and it is quickly absorbed into the body, confirming that the satisfaction of users increases. .
상술한 제조 공정은 하나의 예시이며, 이에 제한되지 않고도 정제 형태의 건강기능식품을 제조할 수 있다. 경우에 따라 도 1의 제조공정도에서 '연합/건조 → 제2차 혼합' 과정을 생략하고 제 1차 혼합 후에 바로 '타정/정제 → 코팅' 과정으로 진행할 수도 있다. 이때 이산화규소는 제1차 혼합물 혹은 코팅액에 포함시킬 수 있다.The above-described manufacturing process is an example, and it is possible to manufacture a health functional food in tablet form without being limited thereto. In some cases, in the manufacturing process diagram of FIG. 1, the process of 'kneading/drying → secondary mixing' may be omitted and the process of 'tabletting/refining → coating' may be performed immediately after the primary mixing. In this case, silicon dioxide may be included in the first mixture or coating solution.
이하, 실시예를 통해 본 발명을 상세히 설명한다. 다만, 하기 실시예는 본 발명을 보다 상세히 설명하기 위한 예일 뿐, 본 발명의 권리범위를 제한하지는 않는다.Hereinafter, the present invention will be described in detail through examples. However, the following examples are only examples for explaining the present invention in more detail, and do not limit the scope of the present invention.
[실시예][Example]
실시예: 건강기능식품의 제조1Example: Manufacture of health functional food 1
하기 표 1에 기재된 배합비를 가지는 원재료를 각각 준비하였다.Raw materials having the mixing ratios shown in Table 1 below were prepared respectively.
(1)산양산삼 분말, 홍삼 분말, 밀크씨슬, 호박산, 흑마늘분말, 울금추출물 분말, 헛개나무열매추출물분말, 영지버섯자실체추출물분말, 아미노산혼합분말, 타우린, 판토텐산칼슘, 비타민B6 염산염, 비타민B1 염산염, 비타민B2, 결정셀룰로오스, 베타인, 스테아린산마그네슘 및 카복시메틸셀룰로오스 칼슘을 혼합하여 제1차 혼합물을 준비한다 (1) Wild wild ginseng powder, red ginseng powder, milk thistle, succinic acid, black garlic powder, turmeric extract powder, raisin raisin fruit extract powder, ganoderma lucidum fruiting body extract powder, amino acid mixture powder, taurine, calcium pantothenate, vitamin B6 hydrochloride, vitamin B1 Prepare a first mixture by mixing hydrochloride, vitamin B2, crystalline cellulose, betaine, magnesium stearate and calcium carboxymethylcellulose
(2)연합기에 제1차 혼합물 70kg을 넣고 70% 주정 14kg을 넣어 5분간 연합한다. (2) Put 70kg of the 1st mixture into a kneader and knead it for 5 minutes by adding 14kg of 70% alcohol.
(3)연합 후 건조기 채반에 4kg식 소분하여 담고, 미리 60℃로 예열한 건조기에서 10시간 동안 건조한다.(3) After union, divide into 4kg meals in a dryer tray, and dry for 10 hours in a dryer preheated to 60 ℃ in advance.
(4)건조된 과립물의 수분함량이 5% 이내인 경우, 정립기로 Mesh는 12~16 수준으로 정립한다. (4) When the moisture content of the dried granules is less than 5%, the size of the mesh is 12 to 16.
(5)혼합기에 과립 건조된 혼합물과 이산화규소를 넣고 2차 혼합을 10 분 동안 실시한다.(5) Put the dried granule mixture and silicon dioxide in a mixer and carry out secondary mixing for 10 minutes.
(6)경도 4.5kgf을 기준으로 하여 정제를 찍어낸다. 타정품의 무게는 627~645 mg로 유지한다.(6) Take out tablets based on the hardness of 4.5kgf. The weight of other products is maintained at 627~645 mg.
(7)히드록시프로필메틸셀룰로오스 및 글리세린지방산에스테르를 주정에 용해하여 코팅액을 미리 준비해 둔다. (7) Prepare a coating solution in advance by dissolving hydroxypropylmethylcellulose and glycerin fatty acid ester in alcohol.
(8)코팅기에 타정된 타정품 약 70~130kg을 넣고 미리 제조된 코팅액을 분사하여 6시간 동안 코팅한다. 코팅시 팬의 온도를 20~60℃로 유지하면서 건조한다.(8) Put about 70 ~ 130kg of tableted product into a coating machine, spray the previously prepared coating liquid, and coat for 6 hours. During coating, dry while maintaining the temperature of the pan at 20 ~ 60 ℃.
비교예: 건강기능식품의 제조2Comparative Example: Manufacture of Health Functional Food 2
하기 표 2에 기재된 배합비를 가지는 원재료를 각각 준비하였다. Raw materials having the mixing ratios shown in Table 2 below were prepared respectively.
(1)상기 표 2의 배합비 대로 준비한 홍삼추출분말, 홍마늘 분말, 브로커리 분말, 밀크씨슬 분말, 호박산 분말, 지구자 엑스분말, 오리목 엑스분말, 황기 엑스분말, 검은콩 엑스분말을 혼합기에 넣고 20~50rpm으로 혼합하여 혼합물을 준비한다.(1) Put red ginseng extract powder, red garlic powder, broccoli powder, milk thistle powder, succinic acid powder, turmeric extract powder, duck neck extract powder, astragalus extract powder, and black bean extract powder prepared according to the mixing ratio in Table 2 above into a mixer. Prepare the mixture by mixing at 20-50 rpm.
(2)상기 혼합물을 정제를 찍어낸다. 타정품의 무게는 627~645 mg로 유지한다.(2) The mixture is taken out into tablets. The weight of other products is maintained at 627~645 mg.
(3)히드록시프로필메틸셀룰로오스(HPMC) 및 글리세린지방산에스테르를 주정에 용해하여 코팅액을 미리 준비해 둔다.(3) Prepare a coating solution in advance by dissolving hydroxypropylmethylcellulose (HPMC) and glycerin fatty acid ester in alcohol.
(4)코팅기에 타정된 타정품 약 70~130kg을 넣고 미리 제조된 코팅액을 분사하여 6시간 동안 코팅한다. 코팅시 팬의 온도를 20~60℃로 유지하면서 건조한다.(4) Put about 70 ~ 130kg of tableted product into the coating machine, spray the previously prepared coating liquid, and coat for 6 hours. During coating, dry while maintaining the temperature of the pan at 20 ~ 60 ℃.
평가예: 관능성 테스트Evaluation example: sensory test
10~60대에 걸친 남성 18명과 여성 10명을 대상으로 상기 실시예 및 비교예에 따라 제조된 건강기능식품 정제 환을 1달간 복용하게 하고 몸의 변화에 대해 설문을 실시하였다.18 males and 10 females in their 10s to 60s were asked to take the functional food tablet pills prepared according to the above Examples and Comparative Examples for 1 month, and a questionnaire was conducted about changes in their bodies.
복용 기준은 실시예에 따른 건강기능식품 정제 환은 1일 1회 2정씩 1달간 복용하였고, 비교예에 따른 건강기능식품 정제 환은 1일 2회, 회당 2정씩 1달간 복용하였다. As for the dosage criteria, the functional food tablet pill according to Example was taken 2 tablets once a day for 1 month, and the functional food tablet pill according to Comparative Example was taken twice a day, 2 tablets per time for 1 month.
1달 이후 아래 표 3 및 표 4의 평가항목에 대해 각각 점수 1~5점을 매기고, 해당 란에 사람의 숫자(인원)를 표시하였다. 총점은 해당 항목의 점수*인원의 총합이다.After 1 month, a score of 1 to 5 was given for each of the evaluation items in Tables 3 and 4 below, and the number of people (number of people) was indicated in the corresponding column. The total score is the sum of the scores for the item * number of people.
표 3의 경우 비교예에 따른 제품 복용 결과이고, 표 4의 경우 실시예에 따른 제품 복용 결과이다.In the case of Table 3, the result of taking the product according to the comparative example, and in the case of Table 4, the result of taking the product according to the example.
평가항목choice (score)
evaluation items
그렇다
(1)very
Yes
(One)
(2)Yes
(2)
(3)commonly
(3)
(4)no
(4)
아니다
(5)very
no
(5)
평가항목choice (score)
evaluation item
그렇다
(1)very
Yes
(One)
(2)Yes
(2)
(3)commonly
(3)
(4)no
(4)
아니다
(5)very
no
(5)
상기 표 3 및 표 4에서 확인할 수 있는 바와 본 발명의 실시예에 따른 건강기능식품을 비교예에 비해 절반으로 복용하였음에도 불구하고 모든 평가항목에 대하여 고르게 본 발명의 건강기능식품의 증상 개선 효과가 뛰어난 것으로 나타났다.As can be seen in Tables 3 and 4, the health functional food according to the embodiment of the present invention showed excellent symptom improvement effects evenly for all evaluation items, even though the health functional food according to the embodiment of the present invention was taken in half compared to the comparative example. appeared to be
즉, 면역력이 증진되어 감기 빈도는 7%, 만성피로는 6%, 대상포진은 7%, 잇몸병은 10%, 구내염은 30%, 기타 염증성 질환은 20%, 음주 후 숙취는 18%, 위장질환은 11%, 다크써클은 6%의 개선 효과를 보여주었다.In other words, the frequency of colds is increased by 7%, chronic fatigue by 6%, shingles by 7%, gum disease by 10%, stomatitis by 30%, other inflammatory diseases by 20%, hangovers after drinking by 18%, stomach and intestines by 18%. Disease showed an improvement effect of 11% and dark circles by 6%.
이와 같이 본 발명에 따라 제조된 건강기능식품은 면역력 증진, 피로회복, 숙취해소에 효과적임을 알 수 있다.As such, it can be seen that the health functional food prepared according to the present invention is effective in improving immunity, recovering from fatigue, and relieving hangover.
Claims (9)
판토텐산칼슘, 비타민B6 염산염, 비타민B1 염산염 및 비타민B2으로 이루어진 제2 조성물 1.8~1.9 중량부; 및
결정셀룰로오스, 베타인, 이산화규소, 스테아린산마그네슘, 카복시메틸셀룰로오스 칼슘, 히드록시프로필메틸셀룰로오스 및 글리세린지방산에스테르로 이루어진 식품첨가물 31.2~31.4 중량부를 포함하여 이루어지는, 산약초를 이용한 건강기능식품.66.5 to 67 parts by weight of a first composition consisting of ginseng powder, milk thistle, succinic acid, black garlic concentrate powder, turmeric extract powder, hovenia raisin fruit extract powder, ganoderma lucidum fruiting body extract powder, amino acid mixture powder, and taurine;
1.8 to 1.9 parts by weight of a second composition consisting of calcium pantothenate, vitamin B6 hydrochloride, vitamin B1 hydrochloride and vitamin B2; and
A health functional food using acid herbs, comprising 31.2 to 31.4 parts by weight of food additives composed of crystalline cellulose, betaine, silicon dioxide, magnesium stearate, calcium carboxymethylcellulose, hydroxypropylmethylcellulose and glycerin fatty acid ester.
상기 삼(ginseng) 분말 10.5 중량%, 상기 밀크씨슬 20.313 중량%, 상기 호박산 30 중량%, 상기 흑마늘농축 분말 1 중량%, 상기 울금추출물 분말 1 중량%, 상기 헛개나무열매추출물 분말 1 중량%, 상기 영지버섯자실체추출물 분말 1 중량%, 상기 아미노산혼합 분말 1 중량%, 상기 타우린 1 중량%, 상기 판토텐산칼슘 0.99 중량%, 상기 비타민B6 염산염 0.33 중량%, 상기 비타민B1 염산염 0.28 중량%, 상기 비타민B2 0.25 중량%, 상기 결정셀룰로오스 21.687 중량%, 상기 베타인 5 중량%, 상기 이산화규소 1.8 중량%, 상기 스테아린산마그네슘 1 중량%, 상기 카복시메틸셀룰로오스 칼슘 1 중량%, 상기 히드록시프로필메틸셀룰로오스 0.77 중량%, 및 상기 글리세린지방산에스테르 0.08 중량%로 포함하는, 산약초를 이용한 건강기능식품.According to claim 1,
10.5% by weight of the ginseng powder, 20.313% by weight of the milk thistle, 30% by weight of the succinic acid, 1% by weight of the black garlic concentrated powder, 1% by weight of the turmeric extract powder, 1% by weight of the Hovenia fruit extract powder, 1% by weight of Ganoderma lucidum fruiting body extract powder, 1% by weight of amino acid mixture powder, 1% by weight of taurine, 0.99% by weight of calcium pantothenate, 0.33% by weight of vitamin B6 hydrochloride, 0.28% by weight of vitamin B1 hydrochloride, and vitamin B2 0.25% by weight, 21.687% by weight of the crystalline cellulose, 5% by weight of the betaine, 1.8% by weight of the silicon dioxide, 1% by weight of the magnesium stearate, 1% by weight of the carboxymethylcellulose calcium, 0.77% by weight of the hydroxypropylmethylcellulose , And 0.08% by weight of the glycerin fatty acid ester, health functional food using acid herbs.
상기 삼(ginseng) 분말은 산양산삼 분말과 홍삼 분말이 중량비율로 1 : 20로 혼합된 것인, 산약초를 이용한 건강기능식품.According to claim 2,
The ginseng powder is a health functional food using mountain medicinal herbs, in which wild wild ginseng powder and red ginseng powder are mixed at a weight ratio of 1: 20.
상기 제1차 혼합물에 주정을 투입하고 연합하여 과립을 만드는 단계;
상기 연합 후 건조하여 수분함량이 5% 이내로 조절하는 단계;
상기 건조 후 이산화규소를 투입하여 제2차 혼합물을 준비하는 단계;
상기 제2차 혼합물을 타정하여 정제를 만드는 단계;
히드록시프로필메틸셀룰로오스 및 글리세린지방산에스테르를 주정에 용해하여 코팅액을 준비하는 단계; 및
상기 정제에 상기 코팅액을 분사하여 코팅하고 건조하는 단계를 포함하는, 산약초를 이용한 건강기능식품의 제조방법.Hemp (ginseng) powder, milk thistle, succinic acid, black garlic concentrate powder, turmeric extract powder, hovenia fruit extract powder, ganoderma lucidum fruiting body extract powder, amino acid mixture powder, taurine, calcium pantothenate, vitamin B6 hydrochloride, vitamin B1 hydrochloride, vitamins preparing a first mixture by mixing B2, crystalline cellulose, betaine, magnesium stearate, and calcium carboxymethylcellulose;
Injecting alcohol into the first mixture and combining them to form granules;
Drying after the coalescence to adjust the moisture content to within 5%;
Preparing a second mixture by adding silicon dioxide after drying;
Tableting the second mixture into tablets;
preparing a coating solution by dissolving hydroxypropylmethylcellulose and glycerin fatty acid ester in alcohol; and
A method for producing a health functional food using acid herbs, comprising the steps of spraying the coating solution on the tablet to coat and dry.
상기 연합하여 과립을 만드는 단계에서 투입되는 상기 주정은 1 중량부에 대해 상기 제1차 혼합물은 5 중량부를 사용하는 것인, 산약초를 이용한 건강기능식품의 제조방법.According to claim 5,
The method of producing a health functional food using acid herbs, wherein the first mixture is used in an amount of 5 parts by weight for 1 part by weight of the alcohol introduced in the step of making the granules by combining.
상기 연합 후 건조하는 단계는 55~65 ℃에서 9~11 시간 진행하는 것인, 산약초를 이용한 건강기능식품의 제조방법.According to claim 5,
The step of drying after the union is to proceed for 9 to 11 hours at 55 ~ 65 ℃, a method for producing a health functional food using acidic herbs.
상기 코팅하고 건조하는 단계는 코팅시 20~60℃를 유지하면서 건조하는 것인, 산약초를 이용한 건강기능식품의 제조방법.According to claim 5,
The coating and drying step is to dry while maintaining 20 ~ 60 ℃ during coating, a method for producing a health functional food using a mountain herb.
상기 제1차 혼합물을 준비하는 단계 이전에 삼(ginseng) 원료의 유효성분을 액상으로 추출한 후 동결건조하여 삼(ginseng) 분말을 준비하는 단계를 추가로 포함하는, 산약초를 이용한 건강기능식품의 제조방법.
According to claim 5,
Prior to the step of preparing the first mixture, extracting the active ingredient of the raw material of ginseng into a liquid phase and then freeze-drying it to prepare ginseng powder, manufacturing method.
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