KR20230065935A - 치료적 접합체 - Google Patents

치료적 접합체 Download PDF

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Publication number
KR20230065935A
KR20230065935A KR1020227046150A KR20227046150A KR20230065935A KR 20230065935 A KR20230065935 A KR 20230065935A KR 1020227046150 A KR1020227046150 A KR 1020227046150A KR 20227046150 A KR20227046150 A KR 20227046150A KR 20230065935 A KR20230065935 A KR 20230065935A
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South Korea
Prior art keywords
conjugate
group
targeting agent
dendrimer
cancer
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KR1020227046150A
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English (en)
Korean (ko)
Inventor
수디르 람나트라오 쉥굴레
데이비드 오웬
리차드 허프톤
크리스 투레흐트
Original Assignee
스타파마 피티와이 리미티드
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Priority claimed from AU2020901833A external-priority patent/AU2020901833A0/en
Application filed by 스타파마 피티와이 리미티드 filed Critical 스타파마 피티와이 리미티드
Publication of KR20230065935A publication Critical patent/KR20230065935A/ko

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    • C08G83/00Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002Dendritic macromolecules
    • C08G83/003Dendrimers
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    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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    • A61K47/6885Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy the conjugate or the polymer being a starburst, a dendrimer, a cascade
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020227046150A 2020-06-03 2021-06-03 치료적 접합체 KR20230065935A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2020901833A AU2020901833A0 (en) 2020-06-03 Therapeutic conjugates
AU2020901833 2020-06-03
PCT/AU2021/050554 WO2021243415A1 (en) 2020-06-03 2021-06-03 Therapeutic conjugates

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KR20230065935A true KR20230065935A (ko) 2023-05-12

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JP (1) JP2023529640A (zh)
KR (1) KR20230065935A (zh)
CN (1) CN115989039A (zh)
AU (1) AU2021284918A1 (zh)
CA (1) CA3180877A1 (zh)
WO (1) WO2021243415A1 (zh)

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WO2023244828A1 (en) * 2022-06-17 2023-12-21 Purdue Research Foundation Fibroblast activation protein-targeted nanoparticle magnetic resonance imaging agents
WO2024007034A2 (en) * 2022-07-01 2024-01-04 The Johns Hopkins University Dendrimer-delivered alpha-particle radiotherapy for treatment of glioblastoma and other cancers in the brain

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