KR20230043819A - 유전자 전사체의 조정제를 사용한 신경계 질환의 치료 - Google Patents

유전자 전사체의 조정제를 사용한 신경계 질환의 치료 Download PDF

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KR20230043819A
KR20230043819A KR1020237000041A KR20237000041A KR20230043819A KR 20230043819 A KR20230043819 A KR 20230043819A KR 1020237000041 A KR1020237000041 A KR 1020237000041A KR 20237000041 A KR20237000041 A KR 20237000041A KR 20230043819 A KR20230043819 A KR 20230043819A
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oligonucleotide
spacer
linkage
stmn2
seq
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Korean (ko)
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다니엘 엘바움
산드라 힝클리
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큐랄리스 코포레이션
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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KR1020237000041A 2020-06-03 2021-06-03 유전자 전사체의 조정제를 사용한 신경계 질환의 치료 Pending KR20230043819A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063033926P 2020-06-03 2020-06-03
US63/033,926 2020-06-03
US202063119717P 2020-12-01 2020-12-01
US63/119,717 2020-12-01
PCT/US2021/035603 WO2021247800A2 (en) 2020-06-03 2021-06-03 Treatment of neurological diseases using modulators of gene transcripts

Publications (1)

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KR20230043819A true KR20230043819A (ko) 2023-03-31

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KR1020237000041A Pending KR20230043819A (ko) 2020-06-03 2021-06-03 유전자 전사체의 조정제를 사용한 신경계 질환의 치료

Country Status (8)

Country Link
US (1) US20230235332A1 (https=)
EP (1) EP4162051A4 (https=)
JP (1) JP2023528435A (https=)
KR (1) KR20230043819A (https=)
AU (1) AU2021284360A1 (https=)
CA (1) CA3185488A1 (https=)
IL (1) IL298647A (https=)
WO (1) WO2021247800A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202208387D0 (en) * 2022-06-08 2022-07-20 Ucl Business Ltd Modified U7 snRNA construct
WO2026080323A1 (en) 2024-10-09 2026-04-16 Quralis Corporation Treatment of neurological diseases using modulators of unc13a gene transcripts

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2266847A1 (en) * 1996-09-24 1998-04-02 Rapigene, Inc. Compositions and methods for enhancing hybridization specificity
US20110046200A1 (en) * 2004-08-03 2011-02-24 Michael T Howard Use of antisense oligonucleotides to effect translation modulation
EP3260540A1 (en) * 2010-11-12 2017-12-27 The General Hospital Corporation Polycomb-associated non-coding rnas
CA3103429A1 (en) * 2018-06-14 2019-12-19 Don W. Cleveland Compounds and methods for increasing stmn2 expression
WO2020150290A2 (en) * 2019-01-14 2020-07-23 President And Fellows Of Harvard College Methods and compositions for restoring stmn2 levels
JP7795914B2 (ja) * 2019-06-03 2026-01-08 クラリス コーポレーション 神経学的疾患を処置するためのオリゴヌクレオチドおよびその使用方法
EP4127172A4 (en) * 2020-03-25 2025-06-04 President and Fellows of Harvard College Methods and compositions for restoring STMN2 levels

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Publication number Publication date
CA3185488A1 (en) 2021-12-09
IL298647A (en) 2023-01-01
EP4162051A4 (en) 2025-07-09
WO2021247800A3 (en) 2022-01-06
EP4162051A2 (en) 2023-04-12
WO2021247800A2 (en) 2021-12-09
AU2021284360A1 (en) 2023-01-19
JP2023528435A (ja) 2023-07-04
US20230235332A1 (en) 2023-07-27

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