KR20230040370A - ″CTL-seq″(CRISPR Tag Linear-seq)로 지정된 뉴클레아제 온-/오프-타겟 편집 위치의 지정 방법 - Google Patents

″CTL-seq″(CRISPR Tag Linear-seq)로 지정된 뉴클레아제 온-/오프-타겟 편집 위치의 지정 방법 Download PDF

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KR20230040370A
KR20230040370A KR1020237005951A KR20237005951A KR20230040370A KR 20230040370 A KR20230040370 A KR 20230040370A KR 1020237005951 A KR1020237005951 A KR 1020237005951A KR 20237005951 A KR20237005951 A KR 20237005951A KR 20230040370 A KR20230040370 A KR 20230040370A
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tag
misc
sequence
seq
phosphorothioate linkage
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매튜 맥닐
롤프 터크
개럿 레티그
엘런 블랙
용밍 선
크리스 세일러
유 왕
키스 건더슨
카일 키니
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인티그레이티드 디엔에이 테크놀로지스 아이엔씨.
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KR1020237005951A 2020-07-23 2021-07-22 ″CTL-seq″(CRISPR Tag Linear-seq)로 지정된 뉴클레아제 온-/오프-타겟 편집 위치의 지정 방법 Pending KR20230040370A (ko)

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US202063055460P 2020-07-23 2020-07-23
US63/055,460 2020-07-23
PCT/US2021/042733 WO2022020567A2 (en) 2020-07-23 2021-07-22 Methods for nomination of nuclease on-/off-target editing locations, designated "ctl-seq" (crispr tag linear-seq)

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EP (1) EP4185708A2 (https=)
JP (2) JP2023535407A (https=)
KR (1) KR20230040370A (https=)
CN (1) CN116194593A (https=)
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GB202013141D0 (en) 2020-08-21 2020-10-07 Univ College Cardiff Consultants Ltd A screening method for the detection of DNA damage
WO2025151661A1 (en) * 2024-01-10 2025-07-17 Sequre Dx, Inc. Methods for single-ended oligonucleotide enrichment and sequencing
WO2026039499A1 (en) 2024-08-14 2026-02-19 Integrated Dna Technologies, Inc. Adaptered-tag blocking oligonucleotides

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US9809904B2 (en) * 2011-04-21 2017-11-07 University Of Washington Through Its Center For Commercialization Methods for retrieval of sequence-verified DNA constructs
CN111254500B (zh) * 2012-12-10 2024-01-23 分析生物科学有限公司 靶向基因组分析的方法
CA2906365A1 (en) * 2013-03-15 2014-09-18 Integrated Dna Technologies, Inc. Rnase h-based assays utilizing modified rna monomers
CN106604994B (zh) * 2014-06-23 2021-12-14 通用医疗公司 通过测序评估的DSBs的全基因组无偏鉴定(GUIDE-Seq)
WO2016030899A1 (en) * 2014-08-28 2016-03-03 Yeda Research And Development Co. Ltd. Methods of treating amyotrophic lateral scleroses
EP3221813A4 (en) * 2014-11-20 2018-04-18 Children's Medical Center Corporation Methods relating to the detection of recurrent and non-specific double strand breaks in the genome
IL269431B2 (en) * 2017-03-23 2025-05-01 Univ Washington Methods for targeted nucleic acid sequence enrichment with applications to error corrected nucleic acid sequencing
CN111868260B (zh) * 2017-08-07 2025-02-21 约翰斯霍普金斯大学 用于评估和治疗癌症的方法和材料
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JP2026048971A (ja) 2026-03-17
JP2023535407A (ja) 2023-08-17
CA3185571A1 (en) 2022-01-27
CN116194593A (zh) 2023-05-30
US20220025365A1 (en) 2022-01-27
EP4185708A2 (en) 2023-05-31
US20250257352A1 (en) 2025-08-14
AU2021311713A1 (en) 2023-03-09
WO2022020567A2 (en) 2022-01-27

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