KR20230037295A - Form for wet dressing and wet dressing used the same that - Google Patents

Abstract

The present invention relates to a new method for manufacturing a foam material for foam type wet dressing by using eco-friendly materials harmless to a human body, wherein the materials include polyvinyl alcohol, which is a water-soluble resin, and foam type wet dressing using a foam material having a new composition which is manufactured by the method to have excellent absorbency, is harmless to a human body, and is environmentally friendly.

Description

Foam material manufacturing method for foam type wet dressing and foam type wet dressing using this foam material {Form for wet dressing and wet dressing used the same that}

The present invention relates to a method for manufacturing a foam material for a foam-type wet dressing and a foam-type wet dressing using the foam material, and more particularly, to a water-soluble and biodegradable polyvinyl alcohol, which is harmless to the human body and is environmentally friendly. It relates to a new method of manufacturing a foam material for a wet dressing and a foam type wet dressing using the foam material.

Skin tissue wounds are generally healed through the process of inflammatory phase → proliferative phase → maturation phase (new tissue formation). It may vary depending on the depth of the wound, but wounds in the epidermal layer usually heal within 6 to 7 days when exposed to air and when maintained in a moist environment. It recovers in about 4 days. The inflammatory response is a step in which bleeding is stopped through hemostasis and bacteria or foreign substances are removed to clean the wound. Afterwards, through a proliferative process, new blood vessels are created in the wound and the defect is filled. Finally, in the mature stage, the formation of inflammatory cells and new blood vessels disappears, and the decomposition and synthesis of collagen are repeated, minimizing the scar area and completely recovering the wound.

After administering first aid to the wound, dress the wound to heal the wound quickly while minimizing scarring. Dressing methods include gauze dressing, which is a traditional method of covering the wound using gauze, and wet dressing, which seals the wound to maintain a moist environment.

The wet dressing method is based on the function of preventing secondary infection by blocking the wound from the external environment, and also absorbs the exudate from the wound to create a moist environment in which moisture and exudate are properly maintained, resulting in the wound surface becoming dry. It inhibits the formation of scabs, thereby allowing wounds to heal quickly.

These wet dressings are classified into hydrocolloid and foam types, and foam-type wet dressings are more suitable for use in wounds with a lot of exudate because they absorb exudates better than hydrocolloid types. This foam-type wet dressing consists of an absorbent layer that absorbs exudate and maintains a moist environment, a waterproof protective layer that covers the absorbent layer to prevent the introduction of microorganisms, and an adhesive layer formed on the bottom of the absorbent layer. Most of the absorbent layer is made of polyurethane foam. It is done.

On the other hand, polyurethane is produced by the reaction of polyol and diisocyanate, and various chemicals such as polyol and diisocyanate as well as crosslinking agents and catalysts are used. Polyurethane does not decompose easily, so it causes environmental pollution.

Republic of Korea Patent Publication No. 10-2021-0098629 (2121. 08. 11.) Republic of Korea Patent Publication No. 10-2021-0001661 (2021. 01. 06) Korea Utility Model Registration No. 20-0422370 (2006. 07. 19)

The present invention has been proposed in view of the above problems, and an object of the present invention is to manufacture a new foam material for foam-type wet dressing using materials harmless to the human body and eco-friendly, including polyvinyl alcohol having water-soluble and biodegradable properties. To provide a method of manufacturing a foam material for a form-type wet dressing and a form-type wet dressing using a foam material manufactured by this method and having excellent absorbency, harmless to the human body, and environmentally friendly foam material of a new configuration.

According to a feature of the present invention, as a method of manufacturing a foam material used as an absorbent layer of a foam-type wet dressing, (1) dissolving 5 to 25 parts by volume of polyvinyl alcohol in 100 parts by volume of water, and 10 to 15 parts by volume of dimethyl sulfoxide A process of preparing a mixture of raw materials by adding 2 to 10 volumes of skin and curdlan and stirring; (2) adding a weak acid and anisaldehyde to the raw material mixture prepared in step (1) and stirring to make the raw material mixture into a paste state; (3) adding a water-soluble foam-forming agent to the mixture of raw materials in a paste form prepared in the step (2) and stirring the mixture; (4) molding the mixture of raw materials in a paste state to which the water-soluble foam-forming agent is added in step (3) into a film form; (5) washing the film formed in step (4) with water to extract and remove the water-soluble foam-forming agent, thereby forming the film into a three-dimensional network structure by open cells; (6) drying the film formed in step (5); And (7) a process of aging the film dried in the step (6); a method for manufacturing a foam material for a foam-type wet dressing, characterized in that it includes, and a foam-type wet dressing using the foam material produced thereby as an absorbent layer is provided do.

The present invention configured as described above is to manufacture a foam material using components harmless to the human body such as dimethyl sulfoxide, curdlan, weak acid, anisaldehyde, and the like along with polyvinyl alcohol having biodegradability as a water-soluble resin. Compared to the conventional polyurethane foam, the foam material manufactured by has the advantage of being environmentally friendly because it is harmless to the human body and has biodegradability. In addition, since it has a three-dimensional network structure by open cells and has excellent absorbency, the foam-type wet dressing prepared using the foam material according to the present invention as an absorbent layer absorbs exudate effectively and creates an environment in which wounds can heal more quickly It has the highest quality possible.

1 is a cross-sectional view of a foam-type wet dressing using a foam material according to the present invention

Hereinafter, the present invention will be described in more detail.

The present invention relates to a method for manufacturing a foam material used as an absorbent layer for absorbing exudate generated from a wound in a foam-type wet dressing, and is manufactured as follows.

1) Raw material mixing process

Add 5 to 25 parts by volume of polyvinyl alcohol to 100 parts by volume of water, heat to about 100 ° C to dissolve polyvinyl alcohol, and then cool to about 5 ° C. Subsequently, 10 to 15 parts by volume of dimethyl sulfoxide and 2 to 10 parts by volume of curdlan are added, stirred well, heated to about 90 ° C, and then cooled to prepare a raw material mixture.

Polyvinyl alcohol (Polyvinyl alcohol) is a water-soluble resin, has biodegradability, is harmless to the human body, and is used for various purposes such as cosmetics, medical implants, and food packaging materials.

Dimethyl sulfoxide (Demethyl sulfoxide) is an organic solvent with strong polarity and high hygroscopicity, has low toxicity to the human body, and has various pharmacological activities including analgesia and anti-inflammatory.

Curdlan, also called β-1,3-glucan, is a high molecular weight polymer of glucose obtained by isolating and purifying polysaccharides produced by Alcaligenes faecalis and Agrobacterium. . It is a white or white-like powder, which forms a thermo-irreversible gel when the water dispersion is heated above 80 °C. Such curdlan is used as a thickener, binder, film forming agent, gelling agent, etc. in jellies, noodles, cakes, and processed meat products. When such curdlan is used, the tensile strength of the foam material to be manufactured is increased, and mechanical properties such as durability are improved.

2) Viscosity control process of raw material mixture

For film formation, it is necessary to increase the viscosity of the mixture of raw materials to reduce fluidity. Add and stir evenly.

Anisaldehyde is an organic compound in which an aldehyde group and a methoxy group are substituted in a benzene ring. It is a colorless, transparent liquid with a strong aroma, harmless to the human body. It is used as a flavoring agent in bakery products and ice cream, and is also used in pharmaceuticals and perfumery.

When treated in this way, the viscosity of the raw material mixture is increased and the raw material mixture is in a paste state.

3) Water-soluble foaming agent mixing process

Add water-soluble foam-forming agents such as starch, dextrin, and water-soluble inorganic salt to the mixture of raw materials in a paste state and disperse them evenly.

The water-soluble foam-forming agent is a component commonly used in wet foaming of synthetic resin, and as will be described later, the film is foamed as it is dissolved in water and removed during the water washing process. Since the water absorption rate of the foam material varies depending on the porosity and pore size of the foam material, the porosity and pore size of the foam material are adjusted by adjusting the addition amount of the water-based foam former so that the foam material has the required water absorption rate.

4) Film forming process

The mixture of raw materials in a paste state is formed into a film. On the release paper, the mixture of raw materials in a paste state is coated to a predetermined thickness using a film manufacturing device such as a knife coater or a comma coater, and then the film is dried.

5) Formation process

The dried film is washed with water to dissolve and remove the bubble forming agent mixed in the mixed solution. In this way, as the bubble forming agent is dissolved in water and removed, micropores of open cells are formed in the film, so that the film has a three-dimensional network structure by the open cells.

6) Drying process

In the above process, the film formed into a three-dimensional network structure is dried in a hot air dryer at about 100° C. to remove moisture remaining in the pores of the film.

7) Aging process

Remove the release paper from the dried film and leave it for 24 hours at 70 ~ 80 ℃ to mature. Through this aging process, mechanical properties such as tensile strength and elongation of the film are improved.

8) Cutting process

The aged film is cut to a desired size to complete the foam material.

The finished product, that is, the foam material, is used as an absorbent layer of a foam-type wet dressing. 1 is a cross-sectional view of a foam-type wet dressing 10 using the foam material prepared as an absorbent layer, as shown, a polyurethane film as a protective layer 14 on the upper surface of the foam material, that is, the absorbent layer 12 are laminated, and an adhesive layer 16 is formed on the bottom to make a foam-type wet dressing.

The present invention having the configuration as described above is to manufacture a foam material using components harmless to the human body such as dimethyl sulfoxide, curdlan, weak acid, anisaldehyde, and the like, along with polyvinyl alcohol having biodegradability as a water-soluble resin. The foam material produced by has the advantage of being environmentally friendly because it is harmless to the human body and has biodegradability compared to conventional polyurethane foam. In addition, since it has a three-dimensional network structure by open cells and has excellent absorbency, the foam-type wet dressing prepared using the foam material according to the present invention as an absorbent layer absorbs exudate effectively and creates an environment in which wounds can heal more quickly It has the highest quality possible.

Claims (2)

As a method of manufacturing a foam material used as an absorbent layer of a foam-type wet dressing,
(1) Dissolving 5 to 25 parts by volume of polyvinyl alcohol in 100 parts by volume of water, adding 10 to 15 parts by volume of dimethyl sulfoxide and 2 to 10 parts by volume of curdlan, and stirring to prepare a raw material mixture;
(2) adding a weak acid and anisaldehyde to the raw material mixture prepared in step (1) and stirring to make the raw material mixture into a paste state;
(3) adding a water-soluble foam-forming agent to the mixture of raw materials in a paste form prepared in the above (2) process and stirring the mixture;
(4) forming a mixture of raw materials in a paste state to which a water-soluble bubble-forming agent is added in step (3) into a film form;
(5) washing the film formed in step (4) with water to extract and remove the water-soluble foam-forming agent, thereby forming the film into a three-dimensional network structure by open cells;
(6) drying the film formed in step (5); and
(7) a process of aging the film dried in the process (6); a method for manufacturing a foam material for a foam-type wet dressing, characterized in that it comprises.
An absorbent layer 12 for absorbing exudate generated from a wound, a protective layer 14 laminated on the upper surface of the absorbent layer 12 to protect the absorbent layer 12, and an adhesive layer formed on the lower surface of the absorbent layer 12 ( In the foam type wet dressing comprising 16),
The absorbent layer 12 is a foam-type wet dressing, characterized in that made of a foam material manufactured by the method according to claim 1.

Images