KR20230035522A - 폐 염증 및 간질성 폐 질병을 치료하기 위한 레리글리타존 - Google Patents
폐 염증 및 간질성 폐 질병을 치료하기 위한 레리글리타존 Download PDFInfo
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- KR20230035522A KR20230035522A KR1020227042096A KR20227042096A KR20230035522A KR 20230035522 A KR20230035522 A KR 20230035522A KR 1020227042096 A KR1020227042096 A KR 1020227042096A KR 20227042096 A KR20227042096 A KR 20227042096A KR 20230035522 A KR20230035522 A KR 20230035522A
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- South Korea
- Prior art keywords
- dione
- phenyl
- methyl
- ethoxy
- thiazolidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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| PCT/IB2021/053651 WO2021220250A1 (en) | 2020-04-30 | 2021-04-30 | Leriglitazone for treating lung inflammation and interstitial lung disease |
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| EP4642456A1 (en) * | 2022-12-28 | 2025-11-05 | Minoryx Therapeutics S.L. | Optimized dosing of leriglitazone |
| WO2024231881A2 (en) * | 2023-05-09 | 2024-11-14 | Minoryx Therapeutics S.L. | Polymorphic forms and formulations of leriglitazone |
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| NZ590774A (en) * | 2008-08-07 | 2012-09-28 | Pulmagen Therapeutics Inflammation Ltd | Substantially pure 5R enantiomers of pioglitazone and rosiglitazone for treating inflammatory respiratory diseases |
| WO2010150014A1 (en) * | 2009-06-24 | 2010-12-29 | Pulmagen Therapeutics (Inflammation) Limited | 5r- 5 -deuterated glitazones for respiratory disease treatment |
| WO2011047048A1 (en) * | 2009-10-14 | 2011-04-21 | Gemmus Pharma, Inc. | Combination therapy treatment for viral infections |
| WO2011073662A1 (en) * | 2009-12-17 | 2011-06-23 | Astrazeneca Ab | Combination of a benzoxazinone and a further agent for treating respiratory diseases |
| EA202091120A3 (ru) | 2014-04-02 | 2020-12-30 | Минорикс Терапьютикс С.Л. | Производные 2,4-тиазолинидона в лечении расстройств центральной нервной системы |
| JP7040798B2 (ja) * | 2016-12-01 | 2022-03-23 | ミノリックス セラピューティクス エセ．エレ． | 非アルコール性脂肪性肝疾患を処置するための５－［［４－［２－［５－（１－ヒドロキシエチル）ピリジン－２－イル］エトキシ］フェニル］メチル］－１，３－チアゾリジン－２，４－ジオン |
| CN112823004A (zh) * | 2018-06-06 | 2021-05-18 | 米尼奥尔克斯治疗有限公司 | 5-[[4-[2-[5-乙酰基吡啶-2-基]乙氧基]苄基]-1,3-噻唑烷-2,4-二酮及其盐的用途 |
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2021
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| WO2021220250A1 (en) | 2021-11-04 |
| MX2022013021A (es) | 2023-01-16 |
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| CN116390725A (zh) | 2023-07-04 |
| JP2023525981A (ja) | 2023-06-20 |
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| EP4142720A1 (en) | 2023-03-08 |
| US20230172921A1 (en) | 2023-06-08 |
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