KR20230005845A - 췌장 신경내분비 종양 검출 - Google Patents
췌장 신경내분비 종양 검출 Download PDFInfo
- Publication number
- KR20230005845A KR20230005845A KR1020227037904A KR20227037904A KR20230005845A KR 20230005845 A KR20230005845 A KR 20230005845A KR 1020227037904 A KR1020227037904 A KR 1020227037904A KR 20227037904 A KR20227037904 A KR 20227037904A KR 20230005845 A KR20230005845 A KR 20230005845A
- Authority
- KR
- South Korea
- Prior art keywords
- methylation
- sample
- dna
- bisulfite
- gp1bb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2523/00—Reactions characterised by treatment of reaction samples
- C12Q2523/10—Characterised by chemical treatment
- C12Q2523/125—Bisulfite(s)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/164—Methylation detection other then bisulfite or methylation sensitive restriction endonucleases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063019751P | 2020-05-04 | 2020-05-04 | |
| US63/019,751 | 2020-05-04 | ||
| PCT/US2021/030635 WO2021226071A2 (en) | 2020-05-04 | 2021-05-04 | Detecting pancreatic neuroendocrine tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20230005845A true KR20230005845A (ko) | 2023-01-10 |
Family
ID=78468349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227037904A Pending KR20230005845A (ko) | 2020-05-04 | 2021-05-04 | 췌장 신경내분비 종양 검출 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230167506A1 (https=) |
| EP (1) | EP4146678A4 (https=) |
| JP (1) | JP7830350B2 (https=) |
| KR (1) | KR20230005845A (https=) |
| CN (1) | CN115551880A (https=) |
| AU (1) | AU2021268631A1 (https=) |
| CA (1) | CA3172143A1 (https=) |
| WO (1) | WO2021226071A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2816122A1 (en) | 2008-02-15 | 2014-12-24 | Mayo Foundation For Medical Education And Research | Detecting neoplasm from a stool sample |
| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| CA2902916C (en) | 2013-03-14 | 2018-08-28 | Mayo Foundation For Medical Education And Research | Detecting neoplasm |
| CN120700143A (zh) | 2014-03-31 | 2025-09-26 | 梅奥医学教育和研究基金会 | 检测结直肠赘生物 |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| US10435755B2 (en) | 2015-03-27 | 2019-10-08 | Exact Sciences Development Company, Llc | Detecting esophageal disorders |
| CN114574585A (zh) | 2015-08-31 | 2022-06-03 | 梅约医药教育及研究基金会 | 检测胃肿瘤 |
| CN108350485A (zh) | 2015-10-30 | 2018-07-31 | 精密科学发展有限责任公司 | 血浆dna的多重扩增检测测定以及分离和检测 |
| CN109563546B (zh) | 2016-05-05 | 2022-09-09 | 精密科学发展有限责任公司 | 通过分析甲基化dna来检测肺肿瘤 |
| KR102892245B1 (ko) | 2017-01-27 | 2025-11-27 | 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 | 메틸화된 dna 분석에 의한 결장 신조직형성의 검출 |
| JP7277460B2 (ja) | 2017-11-30 | 2023-05-19 | マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ | 乳癌の検出 |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| CA3127329A1 (en) | 2019-01-24 | 2020-07-30 | Mayo Foundation For Medical Education And Research | Detecting endometrial cancer |
| US11702704B2 (en) | 2019-10-31 | 2023-07-18 | Mayo Foundation For Medical Education And Research | Detecting ovarian cancer |
| EP4499859A1 (en) * | 2022-03-31 | 2025-02-05 | Illumina, Inc. | Compositions including aqueous amine borane complexes and polynucleotides, and methods of using the same to detect methylcytosine or hydroxymethylcytosine |
| WO2025194302A1 (zh) * | 2024-03-18 | 2025-09-25 | 深圳华大基因股份有限公司 | 差异化甲基化区域组合及应用 |
| WO2026024692A1 (en) * | 2024-07-24 | 2026-01-29 | Guardant Health, Inc. | Direct methylation single-base resolution sequencing of enriched unmethylated dna |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090077685A1 (en) * | 1998-06-16 | 2009-03-19 | Buehler Robert E | Nucleic acid molecules and other molecules associated with plants |
| WO2002018631A2 (de) * | 2000-09-01 | 2002-03-07 | Epigenomics Ag | Diagnose von bestehenden erkrankungen oder der prädisposition für bestimmte erkrankungen |
| EP1604013A4 (en) * | 2003-03-17 | 2009-02-11 | Univ Johns Hopkins | ANOMALALLY METHYLATED GENES IN PANCREATIC CANCER |
| WO2008073303A2 (en) * | 2006-12-07 | 2008-06-19 | Switchgear Genomics | Transcriptional regulatory elements of biological pathways, tools, and methods |
| WO2012175562A2 (en) * | 2011-06-21 | 2012-12-27 | University Of Tartu | Methylation and microrna markers of early-stage non-small cell lung cancer |
| AU2013275761B2 (en) * | 2012-06-14 | 2017-09-28 | Aarhus Universitet | Biomarkers for prostate cancer |
| WO2014160645A2 (en) * | 2013-03-15 | 2014-10-02 | Biotheranostics, Inc. | Neuroendocrine tumors |
| US20180051343A1 (en) * | 2014-08-08 | 2018-02-22 | Ait Austrian Institute Of Technology Gmbh | Thyroid cancer diagnosis by dna methylation analysis |
| US10370726B2 (en) * | 2016-04-14 | 2019-08-06 | Mayo Foundation For Medical Education And Research | Detecting colorectal neoplasia |
| JP7481804B2 (ja) * | 2016-04-14 | 2024-05-13 | マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ | 高度膵異形成の検出 |
| JP7356349B2 (ja) * | 2017-02-28 | 2023-10-04 | マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ | 前立腺癌検出 |
| WO2019010429A1 (en) * | 2017-07-07 | 2019-01-10 | The Trustees Of The University Of Pennsylvania | METHODS OF DIAGNOSING PANCREATIC CANCER |
| US10648025B2 (en) * | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
-
2021
- 2021-05-04 AU AU2021268631A patent/AU2021268631A1/en active Pending
- 2021-05-04 EP EP21800508.0A patent/EP4146678A4/en active Pending
- 2021-05-04 WO PCT/US2021/030635 patent/WO2021226071A2/en not_active Ceased
- 2021-05-04 CA CA3172143A patent/CA3172143A1/en active Pending
- 2021-05-04 US US17/921,710 patent/US20230167506A1/en active Pending
- 2021-05-04 CN CN202180028122.XA patent/CN115551880A/zh active Pending
- 2021-05-04 JP JP2022567116A patent/JP7830350B2/ja active Active
- 2021-05-04 KR KR1020227037904A patent/KR20230005845A/ko active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021268631A1 (en) | 2023-01-05 |
| US20230167506A1 (en) | 2023-06-01 |
| WO2021226071A3 (en) | 2021-12-09 |
| EP4146678A4 (en) | 2025-08-27 |
| WO2021226071A2 (en) | 2021-11-11 |
| JP7830350B2 (ja) | 2026-03-16 |
| CA3172143A1 (en) | 2021-11-11 |
| EP4146678A2 (en) | 2023-03-15 |
| CN115551880A (zh) | 2022-12-30 |
| JP2023524740A (ja) | 2023-06-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| A201 | Request for examination | ||
| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
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| P22-X000 | Classification modified |
St.27 status event code: A-2-2-P10-P22-nap-X000 |